HOME >> BIOLOGY >> NEWS
Can The Economic Promise Of Drug Discovery Continue To Preserve The Suriname Forest?

as antifungal agents. In another example, graduate student John Berger has been able to enhance the anticancer activity of a new compound by synthesizing analogs, reports Kingston. "Now we're looking for others with more activity from which we can make analogs."

Meanwhile, Bristol-Myers Squibb has put more than 3,000 extracts through 32 screens each in six different therapeutic areas, with the result that one promising compound is continuing to be tested.

While looking for potential pharmaceutical products, project scientists conduct ethnobotanical and random botanical collections. Conservation International (CI) researchers collect plants that the shamans use to treat disease and injury. Such ethnobotanical collection is time consuming. The scientists must gain the shamans' trust to be able to go with them to collect plants. Meanwhile, researchers from the Missouri Botanical Garden (MBG) collect plants of interest at random and end up collecting more plants.

"So which collection strategy is the most productive?" the group wondered. The best way to test plants' activity, says Kingston, is to test it against its intended application. "If you have a plant that the shamans say promotes wound healing, you test it for that benefit. But we have not done that because we don't have tests that mimic whole-body responses."

Pharmaceutical companies are interested in the fundamental biochemistry of disease and have highly specific biochemical assays that they believe provide targets for novel compounds.

"We said to ourselves, 'These plants have been picked out over centuries by the shamans, so one would expect them to be more active than plants collected at random.' So we decided to compare the activity of extracts from plants collected by CI and the Missouri Botanical Garden," Kingston says.

Using yeast-based assays, the Virginia Tech researchers found there was a slight benefit to the ethnobotanical app
'"/>

Contact: David G.I. Kingston
dkingston@vt.edu
(540) 231-6570
Virginia Tech
31-Mar-1998


Page: 1 2 3 4

Related biology news :

1. Economic costs of extreme weather, state by state
2. Economic realities depleting arsenal of antiparasitic drugs
3. Economic model to aid alligator farmers
4. Multi Drug Resistant-TB: Russian Economic Collapse Will Lead To Global Spread Of "Ebola With Wings"
5. Good Ergonomics Is Good Economics
6. Penn State Eries Sea Grant To Focus On Ecology, Economic Development
7. New Gene Holds Promise For Controlling Crohns And Other Inflammatory Diseases
8. Continuing Research On Knee Surgery For Horses At Colorado State University Holds Promise Of Helping Humans With Osteoarthritis
9. New Protein-Like Polymer Shows Promise For Blood Vessel Replacement
10. Multicomponent Malaria Vaccine Shows Promise in Laboratory Tests
11. UD Valentine Science: Cell "Dating" Habits May Promise Healthier Hearts

Post Your Comments:
(Date:8/27/2014)... of studies have shown that excessive iron ... Parkinson,s disease. Previous studies from Chunyan Guo ... China have shown that baicalin prevented iron ... metal transporter 1 expression, and increased ferroportin ... rotenone-induced Parkinson,s disease rats. However, the relationship ...
(Date:8/27/2014)... has shown that piglets can be weaned later with ... outcome of the study at the University,s Roseworthy campus, ... is an important finding for pig producers. It allows ... production. , "Sows don,t usually start their oestrous cycles ... piglets have been weaned," says Ms Alice Weaver, PhD ...
(Date:8/27/2014)... is a dreaded bacterium that can be found ... few weeks, 28 persons in Denmark have been infected ... supermarkets. 13 have died. , The bacterium is notoriously ... ability to adapt to changes in its surroundings, says ... with colleagues from the Department of Biochemistry and Molecular ...
Breaking Biology News(10 mins):Piglet weaning age no bar to litter frequency 2Researchers discover why Listeria bacterium is so hard to fight 2Researchers discover why Listeria bacterium is so hard to fight 3
(Date:8/26/2014)... An analysis by Replikins, Ltd. of Pubmed data of ... Pubmed, has revealed extensive conservation and sharing of specific ... of specific Replikin gene structures has permitted the formulation ... for the H5N1 influenza vaccine and the Taura Syndrome ... be effective (1,2). This Dengue vaccine ...
(Date:8/26/2014)... 2014   Lycera Corp ., a biopharmaceutical ... to treat autoimmune disease and cancer based on ... appointment of Harinder Singh , Ph.D., as ... Singh will lead the board,s efforts to provide ... research programs and pipeline of therapies targeting unmet ...
(Date:8/26/2014)... San Francisco, CA (PRWEB) August 26, 2014 ... to reach USD 8,020.1 million by 2020, according to ... demand for personalized medicine and theranostics, and the subsequent ... be key factors driving market growth over the next ... population and chronic diseases such as cancer, coupled with ...
(Date:8/26/2014)... 26, 2014 Genedata, a leading ... and life science research, today announced the ... be held in Asia, Europe, and North America ... companies and leading research organizations will gather for ... case studies, and upcoming challenges in all areas ...
Breaking Biology Technology:Lycera Appoints Harinder Singh, Ph.D., as Chair of Scientific Advisory Board 2Lycera Appoints Harinder Singh, Ph.D., as Chair of Scientific Advisory Board 3World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 2World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 3World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 4World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 5World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 6Thought Leaders to Explore Innovations in SPR & Combination Screening at Genedata Screener User Group Meetings 2Thought Leaders to Explore Innovations in SPR & Combination Screening at Genedata Screener User Group Meetings 3
Cached News: