HOME >> BIOLOGY >> NEWS
Can The Economic Promise Of Drug Discovery Continue To Preserve The Suriname Forest?

as antifungal agents. In another example, graduate student John Berger has been able to enhance the anticancer activity of a new compound by synthesizing analogs, reports Kingston. "Now we're looking for others with more activity from which we can make analogs."

Meanwhile, Bristol-Myers Squibb has put more than 3,000 extracts through 32 screens each in six different therapeutic areas, with the result that one promising compound is continuing to be tested.

While looking for potential pharmaceutical products, project scientists conduct ethnobotanical and random botanical collections. Conservation International (CI) researchers collect plants that the shamans use to treat disease and injury. Such ethnobotanical collection is time consuming. The scientists must gain the shamans' trust to be able to go with them to collect plants. Meanwhile, researchers from the Missouri Botanical Garden (MBG) collect plants of interest at random and end up collecting more plants.

"So which collection strategy is the most productive?" the group wondered. The best way to test plants' activity, says Kingston, is to test it against its intended application. "If you have a plant that the shamans say promotes wound healing, you test it for that benefit. But we have not done that because we don't have tests that mimic whole-body responses."

Pharmaceutical companies are interested in the fundamental biochemistry of disease and have highly specific biochemical assays that they believe provide targets for novel compounds.

"We said to ourselves, 'These plants have been picked out over centuries by the shamans, so one would expect them to be more active than plants collected at random.' So we decided to compare the activity of extracts from plants collected by CI and the Missouri Botanical Garden," Kingston says.

Using yeast-based assays, the Virginia Tech researchers found there was a slight benefit to the ethnobotanical app
'"/>

Contact: David G.I. Kingston
dkingston@vt.edu
(540) 231-6570
Virginia Tech
31-Mar-1998


Page: 1 2 3 4

Related biology news :

1. Economic costs of extreme weather, state by state
2. Economic realities depleting arsenal of antiparasitic drugs
3. Economic model to aid alligator farmers
4. Multi Drug Resistant-TB: Russian Economic Collapse Will Lead To Global Spread Of "Ebola With Wings"
5. Good Ergonomics Is Good Economics
6. Penn State Eries Sea Grant To Focus On Ecology, Economic Development
7. New Gene Holds Promise For Controlling Crohns And Other Inflammatory Diseases
8. Continuing Research On Knee Surgery For Horses At Colorado State University Holds Promise Of Helping Humans With Osteoarthritis
9. New Protein-Like Polymer Shows Promise For Blood Vessel Replacement
10. Multicomponent Malaria Vaccine Shows Promise in Laboratory Tests
11. UD Valentine Science: Cell "Dating" Habits May Promise Healthier Hearts

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/17/2016)... March 17, 2016 ABI Research, the ... the global biometrics market will reach more than ... increase from 2015. Consumer electronics, particularly smartphones, continue ... sensors anticipated to reach two billion shipments by ... Dimitrios Pavlakis , Research Analyst at ABI Research. ...
(Date:3/11/2016)... March 11, 2016 http://www.apimages.com ) - ... Picture is available at AP Images ( http://www.apimages.com ) - ... be used to produce the new refugee identity cards. DERMALOG will ... at CeBIT in Hanover next week.   ... will be used to produce the new refugee identity cards. DERMALOG ...
(Date:3/9/2016)... 9, 2016 Nigeria ... more than 23,000 public service employees either did not ... their salary unlawfully.    --> Nigeria ... that more than 23,000 public service employees either did ... receiving their salary unlawfully.    --> DERMALOG, ...
Breaking Biology News(10 mins):
(Date:5/19/2016)... , May 19, 2016 There ... fully recover given the relentless pressures in pricing and ... in the investors circle though - numerous opportunities are ... of today,s session, ActiveWallSt.com,s presents four names in this ... Vitae Pharmaceuticals Inc. (NASDAQ: VTAE ), Anthera ...
(Date:5/18/2016)... ... May 18, 2016 , ... Shimadzu Scientific Instruments ... University of Toledo. This two-day camp will take place annually starting June 2016. ... of pharmaceutical sciences in preparation for a university academic program. , The ...
(Date:5/18/2016)... ... 18, 2016 , ... Ryan Benton was diagnosed with Duchenne Muscular Dystrophy (DMD) ... to early twenties. DMD is a relatively common progressive genetic disorder, which causes aggressive ... condition was critical. He met with the founder of the Stem Cell Institute ...
(Date:5/17/2016)... , ... May 17, 2016 , ... The Children’s Tumor ... and monuments across the globe will show their support in the fight against neurofibromatosis ... Neurofibromatosis, NF, is a genetic disorder that causes tumors to grow on nerves throughout ...
Breaking Biology Technology:
Cached News: