HOME >> BIOLOGY >> NEWS
Can heart failure impair thinking?

Bethesda, MD Heart failure (HF) is a clinical syndrome characterized by distinctive symptoms and signs resulting from disturbances in cardiac output or from increased venous pressure. According to the National Heart, Lung and Blood Institute, up to three million Americans have heart failure, with 400,000 new cases being diagnosed each year. It is a condition that is slightly more common among men than women and is twice as common among blacks compared to whites.

Background

HF is among the most serious symptom of heart disease, killing about two-thirds of all patients within five years of diagnosis. Patients are treated with mediations such as ACE inhibitors and digitalis so that the heart does not have to work so strenuously to pump blood. HF has other effects as well.

High sympathetic and decreased parasympathetic activities are characteristic of HF and are manifested as blunted baroreceptor activity, diminished parasympathetic effects on the sinoatrial node, increased norepinephrine, decreased heart rate variability, and diminished responsiveness and number of 1-receptors. These characteristics may result from peripheral or central aberrations. The parasympathetic alterations may derive from reduced cardiac muscarinic receptors; however, they also may result from central nervous system (CNS) dysfunction.

The cognitive deficits also suggest CNS dysfunction, possibly developing from ischemic damage as a consequence of HF. The principal neurological deficit of HF patients appears to be delayed recall. This memory dysfunction suggests specific neural damage related to the hippocampus or frontal lobe or associated circuitry, rather than generalized deficits over the entire brain.

Approximately one-half of chronic HF patients exhibit obstructive sleep apnea (OSA) or Cheyne-Stokes breathing during sleep. OSA cases show significant gray matter loss in cerebellar, insular, and cortical areas, which may contribute to abe
'"/>

Contact: Donna Krupa
djkrupa1@aol.com
703-527-7357
American Physiological Society
23-Sep-2003


Page: 1 2 3 4 5 6

Related biology news :

1. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
2. Screen siblings, parents of infants with severe heart abnormalities
3. Recent evolution at a single gene may have brought down heart disease risk in some human groups
4. How do you mend a broken heart?
5. Protemix corporation announces discovery of way to repair hearts damaged by diabetes
6. Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
7. Putting energy into heart protection
8. Rare mutations can significantly increase risk factor for heart disease
9. Smart gene therapy protects against damage from heart attack
10. University of Pittsburgh medical center among first to implant heart assist device
11. Reading hexametric rhyme supports cardiac synchronization, especially after a heart attack

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/27/2017)... 2017   Strategic Cyber Ventures , the industry,s ... a $3.5 million investment in  Polarity , the first ... is DC based and is led by cybersecurity veterans ... Ron Gula , also a longtime cybersecurity veteran ... this series A round of funding. This new funding ...
(Date:2/21/2017)... -- Der weltweite Biobanking-Sektor wird bis zum ... mit mehr als 50 Vertretern aus verschiedenen Branchen wurde aber ... diese Prognose zu realisieren. ... Zu den Schwierigkeiten für ... für die Biobank, die Implementierung Zeit sparender Technologien, ein ...
(Date:2/10/2017)... DUBLIN , Feb 10, 2017 ... PharmaBiotech,s new report "Personalized Medicine - Scientific and Commercial ... ... in personalized medicine. Diagnosis is integrated with therapy for selection ... emphasis on early detection and prevention of disease in modern ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... ... March 23, 2017 , ... Advanced Polymer ... hire of Dr. Sigmund “Sig” Floyd as Vice President ? Global Business Development. ... development activities. , “Dr. Floyd’s career has spanned 30 years in the chemicals ...
(Date:3/22/2017)... CAMBRIDGE, Mass. , March 22, 2017 ... announced that it has eclipsed the 130 million covered ... Cross Blue Shield of Texas . ... stages, the Company continues to enjoy strong payor acceptance ... of its clinical programs and genetic counseling, its industry-leading ...
(Date:3/22/2017)... /PRNewswire/ - FACIT announced a seed stage investment ... start-up created by FACIT focused on developing a ... with non-dilutive capital, achieves a targeted $3.0M financing ... Propellon to accelerate the nomination of a candidate ... entering a strategic partnership for clinical trials in ...
(Date:3/22/2017)... Ca (PRWEB) , ... March 21, 2017 , ... ... clearance of biologics. To acquire information on the desired increase and/or decrease in ... biopharmaceutical industry for rapid N-glycosylation profiling of therapeutic antibodies. , To meet ...
Breaking Biology Technology:
Cached News: