HOME >> BIOLOGY >> NEWS
Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases

dramatically lowering liver damage by the vaccine strain.

Cerus plans to use this doubly attenuated listeria strain as a platform for various types of cancer vaccines. In fact, Cook said, as long as an antigen can be found that stimulates an immune system attack against a cancer, that antigen could be inserted into listeria to create a vaccine.

At the moment, Cerus' preclinical development programs are focused on two novel cancer antigens, according to a recent company press release. Cerus is collaborating with Johns Hopkins University to develop a listeria-based vaccine targeting pancreatic and ovarian cancers that express the Mesothelin antigen, and has partnered with MedImmune, Inc., to develop a listeria-based vaccine targeting the large number of tumors, including breast, prostate and melanoma, that overexpress the antigen EphA2. Both antigen targets have recently been featured in new research reports suggesting their significance as potential targets for cancer treatment.

The listeria-based cancer vaccine work was sponsored by Cerus Corp., with support for Portnoy from the U.S. Public Health Service. Portnoy also serves as a consultant for Cerus. Coauthors on the paper are Dirk Brockstedt, Martin Giedlin, Meredith Leong, Keith Bahjat, Yi Gao, William Luckett, Weiqun Liu and Thoms Dubensky Jr. of Cerus.


'"/>

Contact: Robert Sanders
rls@pa.urel.berkeley.edu
510-643-6998
University of California - Berkeley
29-Sep-2004


Page: 1 2 3 4 5

Related biology news :

1. 16th EORTC NCI AACR Symposium Molecular Targets and Cancer Therapeutics
2. 16th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
3. Cancer gene MYC emerging as key research target
4. Cancer patient, heal thyself
5. USC researcher named General Motors Cancer Research Scholar
6. Fox Chase Cancer Centers Alfred Knudson Jr. named 2004 Kyoto Prize winner
7. Wilex & Fox Chase Cancer Center begin trial w/ novel compound targeting tumor invasion & metastasis
8. Cancer drug resistance research leads to possible therapeutic target for Alzheimers disease
9. Fox Chase Cancer Center research shows kidney cancer can be diagnosed in urine
10. National Cancer Gene Therapy Foundation gives $4.0 million in research grants
11. Dana-Farber launches Center for Applied Cancer Science

Post Your Comments:
(Date:5/18/2013)... increasing number of U.S. children are experiencing gastrointestinal ... research presented at Digestive Disease Week (DDW). ... the Cleveland Clinic Children,s Hospital found that obese ... compared to their lean counterparts. The pattern showed ... be correlated to potential complications associated with obesity, ...
(Date:5/17/2013)... residents of all ages will celebrate the science ... on our daily lives during the inaugural Atlanta ... and educators from local museums, corporations, K-12 schools ... 40 different events for children and adults at ... http://atlantasciencefestival.org . , The annual Atlanta Science ...
(Date:5/17/2013)... Dartmouth College study finds human-caused climate change may ... lizards, contradicting a host of recent studies that ... planet. , The findings, which appear in the ... hope for survival of a creature thought to ... that tropical cold-blooded animals, especially forest lizards, will ...
Breaking Biology News(10 mins):New research identifies risks, interventions for children's GI health 2New research identifies risks, interventions for children's GI health 3First Atlanta Science Festival set for 2014 2Climate change may have little impact on tropical lizards 2
(Date:5/16/2013)... Auckland, New Zealand (PRWEB) May 16, 2013 ... Zealand, was invited to speak to doctors in China about ... across Australia and NZ, this was her first trip to ... , Dr. Hart visited Guangzhou and Fuzhou, home to 12 ... treatments in China is very high at this point in ...
(Date:5/16/2013)... Mass. (PRWEB) May 16, 2013 Cambridge ... Summit from August 19-23, 2013 at the Renaissance Waterfront ... the Summit provide a close-up look at the current ... and ensuring bottom-line quality. Leaders in the field ... ways to produce biopharmaceuticals with greater specificity and efficiency. ...
(Date:5/16/2013)... Ore. , May 16, 2013  HealthSparq, ... many of the nation,s largest regional health plans, ... America,s Health Insurance Plans (AHIP) Institute 2013 conference ... highlight survey results showing how health insurance companies ... for the consumer and marketplace demands for increased ...
(Date:5/16/2013)... HAYWARD, Calif. , May 16, 2013 ... University, Beijing , and the ... www.magceutics.com ) have demonstrated a novel therapy for reversing ... brain magnesium levels, they find significant cognitive improvement in ... to demonstrate a mechanism for reversing cognitive decline for ...
Breaking Biology Technology:The 2013 Bioprocessing Summit to Bring Together International Leaders to Discuss Today's Bioprocess Issues From Cell Line Selection to Manufacturing in Boston, MA 2HealthSparq to Reveal New Healthcare Transparency Benchmark Study at AHIP Institute 2013 2HealthSparq to Reveal New Healthcare Transparency Benchmark Study at AHIP Institute 2013 3Elevation of Brain Magnesium Reverses Memory Deficits in Alzheimer Mice 2Elevation of Brain Magnesium Reverses Memory Deficits in Alzheimer Mice 3
Cached News: