HOME >> BIOLOGY >> NEWS
Carnegie Mellon develops new process for growing bone

PITTSBURGH-- Carnegie Mellon University's Jeffrey Hollinger and his research team will receive $1.12 million over the next four years from the National Institutes of Health (NIH) to develop a new therapy for regenerating bone.

Bone, often called the structural steel and reinforced concrete of the human body, supports the body the way a steel framework supports a skyscraper, and it protects its vital organs the way a cast-concrete roof protects' its building occupants. "Unfortunately, bone loss is an unavoidable consequence of aging, osteoporosis and many traumatic accidents,'' Hollinger said.

To address the challenges of safe and effective therapy to restore form and function to deficient bone architecture, Hollinger's research team at Carnegie Mellon's Bone Tissue Engineering Center has developed an innovative therapy for growing bone by inserting a non-viral gene into the body to induce cells to grow bone.

"We are injecting the NTF gene into a site where bone is deficient via a synthetic hydro-gel made from a hyaluronic acid-based polymer,'' Hollinger said. "The hydro-gel/NTF is non-immunogenic and is designed to restore form and function to bone deficiencies.''

Some of the first pre-clinical trials will involve growing bone in the jaw, said Hollinger. And according to transportation officials, about 10 percent of vehicle accident injuries involve the jaw and the flat bones in the face. "Restoring periodontal bone loss is a high priority for our team, and Bruce Doll, head of the Department of Periodontology at the University of Pittsburgh is leading this challenge,'' Hollinger said.

Through ever-improving surgical techniques, the replacement of bone has been done via bone grafting either from the patient's own body or from animal (usually cow) bone. But because the human body is inclined to reject most 'non-self' grafts, Hollinger's synthetic approach to growing bone will eliminate immune rejections. His research team includes D
'"/>

Contact: Chriss Swaney
swaney@andrew.cmu.edu
412-268-5776
Carnegie Mellon University
13-Aug-2003


Page: 1 2

Related biology news :

1. Carnegie Mellon researcher tests tools for protecting Anacostia River ecosystem from PCBs
2. Carnegie Mellon scientists reveal ways of studying, resolving PCB contamination in US rivers
3. PCB breakdown in rivers depends on sediment-specific bacteria, find Carnegie Mellon U. scientists
4. Carnegie Mellon researchers to demonstrate autonomous robotthat will seek life in Atacama Desert
5. Carnegie Mellon University hosts ACS-PRF summer school on green chemistry
6. Carnegie Mellon neuroscientist develops tool to image brain function at the cellular level
7. Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
8. Carnegie Mellon computational biologist Russell Schwartz receives prestigious CAREER award
9. Carnegie Mellon U biologists identify critical player in yeast ribosome assembly
10. Carnegie Mellon U. develops microgel to recover enzymes for manufacturing, research assays
11. Carnegie Mellon U. conducts first comprehensive proteomic analysis of developing animal

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Carnegie Mellon develops new process for growing bone

(Date:8/18/2015)... Research and Markets ( http://www.researchandmarkets.com/research/9dmm6l/global_biometric ) ... Biometric Authentication & Identification Market: Focus On Modality, ... report to their offering. ... is expected to grow at an estimated CAGR ... over $25 billion (approximately) by 2020 as per ...
(Date:8/12/2015)... , Aug. 12, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced that four of its ... solution, have officially been named FIDO Certified™ by ... of the certification, Synaptics, Natural ID™ fingerprint solutions ... Authentication Framework (UAF) standard and are interoperable among ...
(Date:8/6/2015)... Germany , August 6, 2015 /PRNewswire/ ... SensoMotoric Instruments (SMI) shows the world,s first ... based on Epson,s Moverio BT-200 see-through head mounted display ... new solution, unprecedented quality and efficiency is brought to ... displays. For the first time, professionals and researchers can ...
Breaking Biology News(10 mins):Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 2SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 3
(Date:9/4/2015)... ... September 04, 2015 , ... ... bioprinter, the BioBot 1, at the 2015 TERMIS World Congress in Boston. The ... and biomedical engineering institutions around the world. The printer is revolutionary for its ...
(Date:9/3/2015)... Sept. 3, 2015  Guardant Health®, the leader ... highlighting the performance and clinical utility of Guardant360® ... oral and poster presentations at the International Association ... Conference on Lung Cancer. These abstracts were submitted ... California, Davis; the University of Chicago; Sarah Cannon ...
(Date:9/3/2015)... India , September 3, 2015 ... Instruments Market by System (LC (HPLC, UHPLC, Flash), GC, ... Phase Columns, Syringe Filters, Vials) - Analysis & Global ... Market is expected to reach around 9.223 Billion by ... CAGR of 5.5%. Browse 141 tables and ...
(Date:9/2/2015)... Bermuda , Sept. 2, 2015 Axovant Sciences ... the treatment of dementia, today announced upcoming presentations at three ... PM at the Baird 2015 Healthcare Conference in ... , Thursday, September 10 at 2:00 PM at the ... at the Millennium Broadway Hotel & Conference Center , ...
Breaking Biology Technology:BioBots to Debut Desktop 3D Bioprinter for Living Tissue at TERMIS Global Tissue Engineering Conference in Boston 2BioBots to Debut Desktop 3D Bioprinter for Living Tissue at TERMIS Global Tissue Engineering Conference in Boston 3BioBots to Debut Desktop 3D Bioprinter for Living Tissue at TERMIS Global Tissue Engineering Conference in Boston 4Leading Cancer Centers to Present Clinical Utility Data For Guardant360 At IASLC's 16th World Conference on Lung Cancer in Denver Sept. 6-9 2Leading Cancer Centers to Present Clinical Utility Data For Guardant360 At IASLC's 16th World Conference on Lung Cancer in Denver Sept. 6-9 3Leading Cancer Centers to Present Clinical Utility Data For Guardant360 At IASLC's 16th World Conference on Lung Cancer in Denver Sept. 6-9 4Chromatography Instruments Market Worth $ 9.223 Billion by 2020 2Chromatography Instruments Market Worth $ 9.223 Billion by 2020 3Chromatography Instruments Market Worth $ 9.223 Billion by 2020 4Axovant Sciences To Present At Upcoming Investor Conferences 2Axovant Sciences To Present At Upcoming Investor Conferences 3
Cached News: