HOME >> BIOLOGY >> NEWS
Cell death promotes learning growth

Background. The hippocampal formation has long been associated with the execution of higher-order cognitive functions, and impairment of this structure following severe stress and aging has been linked to cognitive disturbances. In order to understand the involvement of the hippocampal formation in the mediation of normal and pathological behaviors, much attention has recently been devoted to hippocampal neurogenesis. The dentate gyrus of the hippocampal formation has the ability to generate new neurons throughout the entire life. Surviving de novo produced cells develop into granule neurons and integrate into the functional circuitry. Neurogenesis has been proposed to play a role in hippocampal-mediated learning and has been implicated in the appearance of behavioral pathologies associated with the hippocampal formation.

Aim of the work. Although evidence suggest that neurogenesis play a role in spatial learning, the effect of learning on cell proliferation remains unclear. The authors generated and tested the hypothesis that different phases of spatial learning measured in the Morris water maze have distinct actions on cell proliferation. In this task, two phases of learning can be distinguished: an early phase during which performance improves rapidly, and a late phase during which asymptotic levels of performance are reached. These two phases seem to involve different brain processes and consequently may differentially influence neurogenesis.

Results. The authors demonstrated that the late phase of learning has a multifaceted effect on neurogenesis depending on the birth date of new neurons. The number of newly born cells increased contingently with the late phase and a large proportion of these cells survived for at least 4 weeks and differentiated into neurons. In contrast, the late phase learning decreased the number of newly born cells produced during the early phase. This learning-induced decrease in the number of newly
'"/>

Contact: Aimee Midei
molecularpsychiatry@mednet.ucla.edu
310-206-6739
Molecular Psychiatry
26-Nov-2003


Page: 1 2

Related biology news :

1. Key cell-death step found
2. Optimizing proteins death domain halts leukemia in laboratory study
3. Small, Smac-like molecule encourages death of cancer cells
4. Heartless worms hold clues to cardiac arrhythmias, sudden death
5. Ecologists help keep death off the roads
6. Researchers identify gene for a primary form of sudden infant death sydrome (SIDS)
7. Cell death protein has surprising role in cell migration
8. Improved nutrition could prevent more than half of the worlds child deaths annually
9. JGI, VBI help unravel sudden oak death & soybean disease
10. Virginia Bioinformatics Institute researcher advances fight against sudden oak death disease
11. Cell growth and death controlled by single pathway in lymphoma cancer model

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cell death promotes learning growth

(Date:7/28/2014)... TEMPE, Ariz. - Reactions among minerals and organic compounds ... deep carbon cycle, they provide energy for the deep ... life. However, very little is known about how minerals ... Arizona State University have demonstrated how a common mineral ... negating the need for toxic solvents or expensive ...
(Date:7/28/2014)... Solanum pennellii , a wild relative of the domestic ... researchers including the labs headed by Professors Neelima Sinha ... Plant Biology. The new genome information may help breeders ... July 27 in the journal Nature Genetics , ... University in Germany. The UC Davis labs carried out ...
(Date:7/28/2014)... research has identified areas of the Earth that are ... change. , Europe is particularly vulnerable, as it has ... per cent, of any continent in ,refugia, areas ... environmental conditions remain relatively constant during times of great ... are mostly in Scandinavia and Scotland. , The ...
Breaking Biology News(10 mins):Mineral magic? Common mineral capable of making and breaking bonds 2Mineral magic? Common mineral capable of making and breaking bonds 3Study finds Europe's habitat and wildlife is vulnerable to climate change 2
(Date:7/29/2014)... (PRWEB) July 29, 2014 The first ... a next generation approach to robotics. What sets Droidles ... patent pending technology that allows them to communicate, share ... wirelessly over the internet. , “The invention is the ... the little Droidles a life of their own, both ...
(Date:7/29/2014)... Acres, FL (PRWEB) July 29, 2014 ... ex situ lift out specimen preparation solutions, has been ... Trademark Office for specimen manipulation methods incorporating a unique ... 8,740,209. This is the second company patent for ... A. Giannuzzi. , These complementary patents extend ...
(Date:7/28/2014)... July 28, 2014 “2014 ... Lubricant Industry” is a professional and in-depth ... market. The report introduces Lubricant basic information, ... chain structure and industry overview. This research ... domestic market as well as global industry ...
(Date:7/28/2014)... 28, 2014 According ... Market by Products (Consumables, Instruments, Services), Methods (Phenotypic, Genotypic), Applications (Pharmaceutical, ... (Detection, Characterization) - Global Forecasts to 2019" ... is estimated at $896.5 Million in 2014 ... by 2019, growing at a CAGR of ...
Breaking Biology Technology:Droidles, the Social Network of Robots and Open Source Platform for the Internet of Things, Launches for Crowd Funding on IndieGoGo.com 2EXpressLO LLC Granted Second U.S. Patent for Innovative Specimen Preparation Methods 2Lubricant Market & Adhesion Promoter Industry (Globa, China) Analysis Now Available at DeepResearchReports.com 2Lubricant Market & Adhesion Promoter Industry (Globa, China) Analysis Now Available at DeepResearchReports.com 3Lubricant Market & Adhesion Promoter Industry (Globa, China) Analysis Now Available at DeepResearchReports.com 4Microbial Identification Market worth $1,194.1 Million by 2019 2Microbial Identification Market worth $1,194.1 Million by 2019 3
Cached News: