HOME >> BIOLOGY >> NEWS
Cells from adult bone marrow can be converted into brain stem cells for transplantation

SAN FRANCISCO Hope for people with Parkinson's disease, Alzheimer's disease, stroke and other neurodegenerative diseases may ultimately come from their own bodies. Research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 May 1, 2004, shows that cells taken from adult human bone marrow can be converted into brain stem cells that meet the criteria for transplantation into the brain.

"It's exciting to think that some day a person with Alzheimer's disease could use their own bone marrow to create brain cells that could potentially restore their functioning and make up for cells that were lost," said study author and neurologist Alexander Storch, MD, of the University of Ulm in Ulm, Germany.

Use of the cells from adult human bone marrow, called stromal cells, eliminates the ethical and logistical issues that arise with the use of cells from fetal tissue, Storch said. And use of cells from bone marrow that would be converted and transplanted into the same person's brain eliminates ethical issues and immune-system problems that can arise when the body rejects cells from an outside source.

For the study, the researchers took the adult human bone marrow stromal cells and cultured them with growth factors.

Other benefits of this process are that the cells can be converted quickly within a few weeks and a small amount of bone marrow can produce a large amount of converted cells, Storch said.

More research is needed before the converted cells can be tested in humans. Animal studies are under way to explore the regenerative potential of the converted cells in animal models of acute and chronic neurodegenerative disorders, such as stroke and Parkinson's disease. The researchers also need to determine the best way to administer the cells into the brain.


'"/>

Contact: Kathy Stone
kstone@aan.com
651-695-2763
American Academy of Neurology
29-Apr-2004


Page: 1

Related biology news :

1. Cells may shoot messenger to halt protein production
2. Cells ability to open bloods floodgates hinges on unexpected factors
3. Cells ability to live without oxygen give clues for treating major diseases
4. Cells use patch to heal tears, avoid destruction and disease
5. Food for thought: Cells dine on their own brains to stay fit and trim
6. Cells in patients noses hold potential to restore function in spinal cord injury
7. Cells on the verge of suicide
8. Cells from human umbilical cord blood help rats recover from stroke faster, new study finds
9. Researchers Propose A Revolutionary New Theory About The Way Cells Communicate
10. Bone Marrow Gives Rise To Functioning Liver Cells, University Of Pittsburgh Scientists Discover
11. Researchers Discover How The Immune System Shuts Down Faulty T Cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/8/2020)... Ariz. (PRWEB) , ... January 08, 2020 , ... ... therapies, is now offering complimentary overnight shipping to its nationwide practice network ... biologics, but also due to volume in its Network the biologics themselves are ...
(Date:12/30/2019)... ... December 30, 2019 , ... Cure Now ? Instead of ... disease is the 6th leading cause of death in the United States. , ... or other dementia. ,     These caregivers provided an estimated 18.5 billion hours ...
(Date:12/18/2019)... ... December 17, 2019 , ... EconoFact, a non-profit media initiative ... Fletcher School, Tufts University, is pleased to announce a collaboration with Macmillan Learning ... using Macmillan Learning’s acclaimed series of economics textbooks. , Under the agreement, Macmillan ...
Breaking Biology News(10 mins):
(Date:1/7/2020)... United Kingdom (PRWEB) , ... January 07, 2020 ... ... of recombinant antibody products and services, today announced the launch of its VivopureX™ ... of popular antibody clones, many originally obtained from rats or hamsters, which Absolute ...
(Date:1/7/2020)... ... 2020 , ... ABCT , the Accelerator for Biosciences ... participate in the annual program. Twelve ventures will participate in the 6.5-month-long program ... All startups will receive an entrepreneur coach, access to active business professionals and ...
(Date:12/27/2019)... EGG HARBOR TOWNSHIP, N.J. (PRWEB) , ... December ... ... premier manufacturer of custom built, helium-based leak testing instruments for the Pharmaceutical, Biotechnology, ... its first calendar year under new management . Following acquisition by CLJ ...
(Date:12/18/2019)... ... December 17, 2019 , ... ... is pleased to announce that it has hired Dr. Alia Orbin, Ph.D., J.D., ... is experienced in the preparation, filing and prosecution of patent applications related to ...
Breaking Biology Technology:
Cached News: