HOME >> BIOLOGY >> NEWS
Chemical engineers discover filtration system to help biotech industry

Chemical engineers at New Jersey Institute of Technology (NJIT) have developed a new filtration system to enable scientists and engineers to separate and purify two different kinds of proteins having relatively close molecular weight. Until now, doing such separations with membrane filtration was impossible. This research was reported in the June 20, 2004 issue of Biotechnology and Bioengineering.

"This is good news," said Kamalesh K. Sirkar, PhD, distinguished professor of chemical engineering and the project's lead researcher. "To separate the good from the bad proteins is an important engineering breakthrough. We believe that pharmaceutical companies will immediately be able to put our research to work."

Before this invention, proteins had to differ five to six times in their molecular weight, before a scientist or engineer could separate them using a process called ultra-filtration.

"Now using a new kind of membrane that we invented at NJIT, the proteins can have almost the same molecular weight," said Sirkar. The process also will be more cost-effective because the machines can run on a continuous basis.

"The reason we think this process will be important to the industry is because purification of protein is important to its end use," said Sirkar. Impure proteins can't be used in any biopharmaceutical applications. However, when scientists in the past have gone to separate proteins and remove impurities by chromatography, costs have escalated.

NJIT has funded this research to date. The next step is to seek outside funding because more work needs to be done. "We know the process will work with a mixture of two proteins. But, Sirkar speculated, will it work if the mixtures contain three or four proteins? More questions include: can it be used on viruses or endotoxins the outer coating of a particular type of bacteria? Will the process work with non-biological macromolecules such as dextran?
'"/>

Contact: Sheryl Weinstein or Roslyn Roberts
roslyn.roberts@njit.edu
973-596-3433
New Jersey Institute of Technology
19-Aug-2004


Page: 1 2

Related biology news :

1. Chemical engineering grad students will take notable national awards
2. Chemical derived from vitamin-E shows early promise as cancer drug
3. Chemical genetics identifies SARS inhibitors
4. Chemical signals health of brain cells Symposium
5. Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
6. NIH roadmap for biomedical research focus of chemists at American Chemical Society meeting
7. American Chemical Society media registration
8. Chemical Society announces EPA awards for environmentally friendly technology
9. NIH launches first center in Nationwide Chemical Genomics Network
10. Chemical reaction in birds provides sense of direction during migratory flights
11. Annual Chemical Biology Symposium at Yale May 14, 2004

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2019)... (PRWEB) , ... August 21, 2019 , ... ... E. coli cell line for rapid and low-cost biomanufacturing of complex protein therapeutics, ... Formerly a member of AbSci's Scientific Advisory Board, Dr. Larimore brings more than ...
(Date:8/15/2019)... ... August 15, 2019 , ... Deep Science Ventures ... Food and Agriculture practice, a new unit dedicated to building 100 companies over the ... raw materials and supply chains. , Deep Science Ventures was founded to create ...
(Date:8/14/2019)... ... August 14, 2019 , ... Carterra® ... they have opened a Customer Experience Center (CEC) and office in Munich, Germany. ... office. , The Munich CEC will be a place for researchers throughout Europe ...
Breaking Biology News(10 mins):
(Date:9/17/2019)... ... September 16, 2019 , ... MyBioGate Global Healthcare Innovation ... Biotech Week Boston, a forum organized by MyBioGate, Inc. and CUBIO Innovation Center ... a careful process of evaluation, twelve companies out of over 200 applications were ...
(Date:9/11/2019)... (PRWEB) , ... September 10, 2019 , ... ... broadcast 1Q/2020 will educate about the latest developments in genome sequencing analysis. Check ... about the innovation taking place at Rivermap Research & Consulting and will explore ...
(Date:9/8/2019)... NEW YORK (PRWEB) , ... September 04, 2019 ... ... New York Academy of Sciences announced today the three Winners and ... Supporting outstanding postdoctoral scientists from academic research institutions across New York, New Jersey, ...
(Date:9/2/2019)... N.J. and LIÉGE, Belgium (PRWEB) , ... September ... ... of solutions for epigenetics research and in vitro diagnostics, has launched the industry’s ... uncover the underlying biological meaning of epigenetic data and other data types. ...
Breaking Biology Technology:
Cached News: