HOME >> BIOLOGY >> NEWS
Children's Hospital Boston researchers use therapeutic cloning to create functional tissue in cows

Boston - In a study published in the July issue of Nature Biotechnology, available on the internet June 3, researchers from Children's Hospital Boston and colleagues demonstrated that laboratory-engineered tissues created from heart, skeletal, and renal cells cloned from cows, then transplanted back into the animals, developed into functional tissues and caused no signs of rejection.

"The study is proof of principle that therapeutic cloning can be used to create tissues without the threat of rejection," says Anthony Atala, M.D., director of Tissue Engineering at Children's Hospital Boston and the senior author on the paper. "While more work needs to be done, this demonstrates the potential use of this technology."

As many as 3,000 Americans die every day from diseases that may someday be treatable with tissues created through stem cells, according to the Centers for Disease Control. Somatic cell nuclear transfer ("therapeutic cloning"), which is one way to derive stem cells, shows potential in generating functional replacement cells such as insulin-producing cells associated with diabetes. It also shows promise in reconstituting more complex tissues and organs, such as blood vessels, myocardial "patches," kidneys, and even entire hearts. Additionally, it has the potential to eliminate the rejection responses associated with transplantation of "non-self" tissues, and thus the need for immunosuppressive drugs, which carry the risk of serious and potentially life-threatening complications and enormous cost to the United States health care system.

In the study, researchers obtained cow oocytes (donor eggs from cow ovaries) and removed and discarded the nuclei, which contain the cells' genetic material, leaving behind just the shell. A skin cells from the cow's ears was placed inside the egg shell and burst with electrical energy to expand the cells. That induces the one skin cell to become several cells. The resulting blastocysts (4-day old emb
'"/>

Contact: Elizabeth Andrews and Mary-Ellen Bain
617-355-6420
Children's Hospital Boston
2-Jun-2002


Page: 1 2

Related biology news :

1. Childrens Hospital Boston receives more than $10 million to help make smallpox vaccine safer
2. Childrens eating patterns show striking changes in two decades
3. Childrens Memorial, TGen announce partnership
4. Federal grant supports advances in infant heart disease at Childrens Hospital of Philadelphia
5. Packard Childrens Hospital gift creates new biotech research center for childrens health
6. Novel gene therapy on the horizon, says Brenner Childrens Hospital pediatrician
7. Childrens Hospital Boston researchers regenerate zebrafish heart muscle
8. Childrens book explores why animals stay home to help
9. Hopkins Childrens Center researchers find cause for common kind of dwarfism
10. Transplanted human stem cells develop into broad range of tissues, persist over a year in research at The Childrens Hospital of Philadelphia
11. Immunologist at the Childrens Hospital of Philadelphia receives national award in clinical laboratory immunology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2019)... (PRWEB) , ... August 21, 2019 , ... ... E. coli cell line for rapid and low-cost biomanufacturing of complex protein therapeutics, ... Formerly a member of AbSci's Scientific Advisory Board, Dr. Larimore brings more than ...
(Date:8/15/2019)... ... August 15, 2019 , ... Deep Science Ventures ... Food and Agriculture practice, a new unit dedicated to building 100 companies over the ... raw materials and supply chains. , Deep Science Ventures was founded to create ...
(Date:8/14/2019)... ... August 14, 2019 , ... Carterra® ... they have opened a Customer Experience Center (CEC) and office in Munich, Germany. ... office. , The Munich CEC will be a place for researchers throughout Europe ...
Breaking Biology News(10 mins):
(Date:9/11/2019)... ... September 09, 2019 , ... Tunnell ... government agencies, announced that its president and CEO Maryann Gallivan has been accepted ... , The Forbes Council accepted Gallivan based on the role she and ...
(Date:9/8/2019)... (PRWEB) , ... September 04, 2019 , ... ... York Academy of Sciences announced today the three Winners and six Finalists ... postdoctoral scientists from academic research institutions across New York, New Jersey, and Connecticut ...
(Date:8/29/2019)... ... August 28, 2019 , ... DuPont Nutrition ... solutions to attendees at the International Baking Industry Expo, September 8 to 11, ... optimizing production efficiency to cost and waste reduction and from maintaining freshness throughout ...
(Date:8/23/2019)... ... 2019 , ... The EnozoPro® converts ordinary tap water into a sanitizing spray ... hard surfaces including E. Coli, Salmonella, MRSA, Listeria and Legionella. It works as a ... the product page at rovingblue.com , ”At Enozo, our mission is to develop solutions ...
Breaking Biology Technology:
Cached News: