Children's Memorial, TGen announce partnership

interpretation of genomes, or gene sequences, and their function. Progress in the last decade has allowed scientists to examine the genes that are expressed or suppressed in cells and compare the differences between normal cells and those that contribute to disease. TGen provides Children's Memorial's researchers access to a range of genomic, genetic and proteomic technologies, bioinformatics, high-throughput sequencing, and gene expression profiling capabilities.

"Our partnership with TGen recognizes the critical role that science and technology play in unraveling the genetic components of common and complex children's diseases, which could be translated to the early detection and management of related adult diseases," Hendrix said. "Our hope is to provide new methods of diagnosis and treatment, leading to individualized medicine for patients."

Hendrix, who took over the reins at Children's Memorial's research institute in January, is an internationally respected cancer researcher whose work includes the molecular classification of aggressive tumor cells, which has led to the discovery of their embryonic-like properties, called plasticity -- a major insight into the basic mechanisms underlying cancer progression.

Before founding TGen in 2002, Trent served for 10 years at the world's largest biomedical research institute -- the National Institutes of Health in Bethesda, Md. There, he founded and directed the laboratory division of the federal agency in charge of coordinating and finalizing the Human Genome Project. His research focuses on genetic changes that increase one's risk for developing cancer.

Children's Memorial Institute for Education and Research is one of 13 interdisciplinary research centers and institutes of Northwestern University's Feinberg School of Medicine, and all principal investigators at the institute are full-time faculty members at Feinberg. The institute is the research arm of Children's Memorial Medi

Contact: Julie Pesch
Children's Memorial Hospital

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