HOME >> BIOLOGY >> NEWS
Chimp vs. human DNA: what's in the 1% difference

ITHACA, N.Y. -- Nearly 99 percent alike in genetic makeup, chimpanzees and humans might be even more similar were it not for what researchers call "lifestyle" changes in the 6 million years that separate us from a common ancestor. Specifically, two key differences are how humans and chimps perceive smells and what we eat.

A massive gene-comparison project involving two Cornell University scientists, and reported in the latest issue of the journal Science (Dec. 12, 2003), found these and many other differences in a search for evidence of accelerated evolution and positive selection in the genetic history of humans and chimps.

In the most comprehensive comparison to date of the genetic differences between two primates, the genomic analysts found evidence of positive selection in genes involved in olfaction, or the ability to sense and process information about odors. "Human and chimpanzee sequences are so similar, we were not sure that this kind of analysis would be informative," says evolutionary geneticist Andrew G. Clark, Cornell professor of molecular biology and genetics. "But we found hundreds of genes showing a pattern of sequence change consistent with adaptive evolution occurring in human ancestors." Those genes are involved in the sense of smell, in digestion, in long-bone growth, in hairiness and in hearing. "It is a treasure-trove of ideas to test by more careful comparison of human and chimpanzee development and physiology," Clark says.

The DNA sequencing of the chimpanzee was performed by Celera Genomics, in Rockville, Md., as part of a larger study of human variation headed by company researchers Michele Cargill and Mark Adams.

Celera generated some 18 million DNA sequence "reads," or about two-thirds as many as were required for the first sequencing of the human genome. Statistical modeling and computation was done by Clark and by Rasmus Nielsen, a Cornell assistant professor of biological statistics and computational biolo
'"/>

Contact: Roger Segelken
hrs2@cornell.edu
607-255-9736
Cornell University News Service
19-Dec-2003


Page: 1 2 3

Related biology news :

1. Chimp genome assembled
2. Chimpanzees with little or no human contact found in remote African rainforest
3. Chimpanzee stone tool site excavated
4. Chimpanzee virus may be key to better vaccines, study shows
5. Chimpanzee subspecies are genetically mixed and more diverse than humans, according to research in 5 November 1999 Science
6. Protestors Are Up In Arms Over Experiments That Give Chimps AIDS
7. Similarities Found In Human, Chimp Brains; Columbia, Mount Sinai, NIH Scientists Find Region That Controls Language Identical In Both Species
8. One Chimp Can Perceive States Of Awareness In Others
9. Climate change plus human pressure caused large mammal extinctions in late Pleistocene
10. Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
11. Most recent common ancestor of all living humans surprisingly recent

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/10/2016)... -- --> --> ... Access Management Market by Component (Provisioning, Directory Services, Password ... Size, by Deployment, by Vertical, and by Region - ... is estimated to grow from USD 7.20 Billion in ... Compound Annual Growth Rate (CAGR) of 12.2% during the ...
(Date:3/9/2016)... 9, 2016 Nigeria ... more than 23,000 public service employees either did not ... their salary unlawfully.    --> Nigeria ... that more than 23,000 public service employees either did ... receiving their salary unlawfully.    --> DERMALOG, ...
(Date:3/3/2016)... March 3, 2016  FlexTech, a SEMI Strategic Association ... Innovation, Research & Development, Leadership in Education, and, in ... the 9 th year of the FLEXI Awards ... and individuals from past years . Judging was ... pre-described set of criteria, by a panel of non-affiliated, ...
Breaking Biology News(10 mins):
(Date:5/23/2016)... , May 23, 2016 Zimmer Biomet Holdings, ... healthcare, today announced that its Board of Directors has approved ... the second quarter of 2016. The cash ... about July 29, 2016 to stockholders of record as of ... of dividends are subject to approval of the Board of ...
(Date:5/23/2016)... , ... May 23, 2016 , ... ... organization focused on molecular nanotechnology, announced the winners for the 2015 Foresight Institute ... Richard Feynman, are given in two categories, one for experiment and the other ...
(Date:5/20/2016)... , ... May 20, 2016 , ... Korean researchers say ... it may offer a new way to treat the disease. Surviving Mesothelioma has just ... , Scientists from several Korean institutions based their mesothelioma study on the fact ...
(Date:5/19/2016)... 19, 2016 There is no ... given the relentless pressures in pricing and lack in ... investors circle though - numerous opportunities are up for ... session, ActiveWallSt.com,s presents four names in this sector: Portola ... Inc. (NASDAQ: VTAE ), Anthera Pharmaceuticals Inc. ...
Breaking Biology Technology:
Cached News: