HOME >> BIOLOGY >> NEWS
Chimp vs. human DNA: what's in the 1% difference

ITHACA, N.Y. -- Nearly 99 percent alike in genetic makeup, chimpanzees and humans might be even more similar were it not for what researchers call "lifestyle" changes in the 6 million years that separate us from a common ancestor. Specifically, two key differences are how humans and chimps perceive smells and what we eat.

A massive gene-comparison project involving two Cornell University scientists, and reported in the latest issue of the journal Science (Dec. 12, 2003), found these and many other differences in a search for evidence of accelerated evolution and positive selection in the genetic history of humans and chimps.

In the most comprehensive comparison to date of the genetic differences between two primates, the genomic analysts found evidence of positive selection in genes involved in olfaction, or the ability to sense and process information about odors. "Human and chimpanzee sequences are so similar, we were not sure that this kind of analysis would be informative," says evolutionary geneticist Andrew G. Clark, Cornell professor of molecular biology and genetics. "But we found hundreds of genes showing a pattern of sequence change consistent with adaptive evolution occurring in human ancestors." Those genes are involved in the sense of smell, in digestion, in long-bone growth, in hairiness and in hearing. "It is a treasure-trove of ideas to test by more careful comparison of human and chimpanzee development and physiology," Clark says.

The DNA sequencing of the chimpanzee was performed by Celera Genomics, in Rockville, Md., as part of a larger study of human variation headed by company researchers Michele Cargill and Mark Adams.

Celera generated some 18 million DNA sequence "reads," or about two-thirds as many as were required for the first sequencing of the human genome. Statistical modeling and computation was done by Clark and by Rasmus Nielsen, a Cornell assistant professor of biological statistics and computational biolo
'"/>

Contact: Roger Segelken
hrs2@cornell.edu
607-255-9736
Cornell University News Service
19-Dec-2003


Page: 1 2 3

Related biology news :

1. Chimp genome assembled
2. Chimpanzees with little or no human contact found in remote African rainforest
3. Chimpanzee stone tool site excavated
4. Chimpanzee virus may be key to better vaccines, study shows
5. Chimpanzee subspecies are genetically mixed and more diverse than humans, according to research in 5 November 1999 Science
6. Protestors Are Up In Arms Over Experiments That Give Chimps AIDS
7. Similarities Found In Human, Chimp Brains; Columbia, Mount Sinai, NIH Scientists Find Region That Controls Language Identical In Both Species
8. One Chimp Can Perceive States Of Awareness In Others
9. Climate change plus human pressure caused large mammal extinctions in late Pleistocene
10. Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
11. Most recent common ancestor of all living humans surprisingly recent

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Chimp human DNA what the difference

(Date:7/21/2014)... have meaning? If you say "dog" to a friend, ... University philosopher Elliott Wagner aims to address these types ... long-standing philosophical questions about semantic meaning. Wagner, assistant professor ... are collaborating to use game theory to analyze communication ... a cappuccino at a coffee shop, I usually don,t ...
(Date:7/21/2014)... to climate change, due to greenhouse gasses emitted by ... the rise and that beef cattle are responsible for ... animals. It is published by Climactic Change . ... it comes to climate change. It is released by ... portion of greenhouse gas totals. But methane and nitrous ...
(Date:7/21/2014)... the strength of immune response, rather than with the ... the virus, might be a better way to reduce ... Washington, Seattle. She and her collaborators have now taken ... H7N9 influenza, and their work has already led to ... strain. The research is published ahead of print in ...
Breaking Biology News(10 mins):Philosopher uses game theory to understand how words, actions acquire meaning 2Climate: Meat turns up the heat 2Potential new flu drugs target immune response, not virus 2
(Date:7/18/2014)... N.Y. , July 18, 2014 Regeneron ... its second quarter 2014 financial and operating results on ... open.  The Company will host a conference call and ... Conference Call InformationTo access this call, ... link to the webcast may be accessed from the ...
(Date:7/18/2014)... is, most of the atoms in our environment are ... outer parts of atoms equals the number of protons ... more electrons are plucked away from the atoms, the ... the nucleus. This enhanced pull, causing the atoms ... less vulnerable to the distractions of their environment, making ...
(Date:7/18/2014)... (PRWEB) July 18, 2014 Global ... with US offices in Cambridge, MA, announces the ... Assay and Software product that leverages the power ... the Illumina® MiSeq sequencing platform. The assay and ... Children’s Hospital of Philadelphia (CHOP) and will include ...
(Date:7/18/2014)... 18, 2014 The International Wheat Genome Sequencing ... a draft sequence of the bread wheat genome. The ... and evolution of the large, complex genome of the ... genetic blueprint is an invaluable resource to plant science ... at their disposal a set of tools enabling them ...
Breaking Biology Technology:Highly charged ions 2Highly charged ions 3Highly charged ions 4Omixon Launches Holotype HLA for NGS-based HLA Genotyping 2Omixon Launches Holotype HLA for NGS-based HLA Genotyping 3Genetic Blueprint of Bread Wheat Genome Unveiled 2Genetic Blueprint of Bread Wheat Genome Unveiled 3
Cached News: