HOME >> BIOLOGY >> NEWS
Cholesterol Inhibitors In Garlic Identified

University Park, Pa. --- Penn State nutrition researchers have identified a group of chemicals in garlic that decreases cholesterol production by liver cells 40 to 60 percent in laboratory tests.

The study is among the first to pinpoint the specific garlic constituents that may be responsible for the cholesterol-lowering effects observed by researchers earlier in both animal and human feeding studies.

Dr. Yu-Yan Yeh, Penn State professor of nutrition, presented the findings today (Nov. 16) at a conference on "Recent Advances on the Nutritional Benefits Accompanying the Use of Garlic as a Supplement" at the Marriott Newport Center, Newport Beach, Calif.

The conference is a continuing and distance education service of the Penn State College of Health and Human Development Department of Nutrition in cooperation with Wakunaga of America Co. Ltd. The conference is supported by Wakunaga, National Cancer Institute and Rexall-Sundown, Inc.

Yeh's paper, "Allyl Sulfur Compounds of Garlic Inhibit Cholesterol Biosynthesis," was one of six offered in the session on Cardiovascular Benefits of Garlic. His co-author is Lijuan Liu, a doctoral candidate in nutrition at Penn State.

Yeh and Liu identified a group of three water soluble, sulfur-containing, garlic constituents (S-allyl cysteine, S-ethyl-cysteine and S-propyl cysteine) that decreased cholesterol production in cultured rat liver cells by 40 to 60 percent.

The Penn State scientist noted that he used fresh garlic extracts in his recent studies. Deodorized aged garlic extract consists mostly of the same water soluble, sulfur-containing chemicals, he said.

In Yeh's earlier feeding studies with rats, aged garlic extract reduced blood cholesterol by 15 percent. In the human studies, 34 men who took deodorized garlic capsules for five months showed a 7 percent drop in total blood cholesterol levels and a 12 percent drop in LDL or so-called "bad
'"/>

Contact: Barbara Hale
bah@psu.edu
814-865-9481
Penn State
16-Nov-1998


Page: 1 2

Related biology news :

1. Cholesterol lowering drug effective in treating most common form of multiple sclerosis
2. Cholesterol-independent benefits of statins in cardiac hypertrophy
3. Cholesterol levels not necessarily indicative of cardiac health
4. Women With Low Cholesterol May Be At Risk For Depression And Anxiety
5. Structure Of HDL Cholesterol Determined
6. Discovery Of A Molecule That Controls Bile Acids May Lead To New Cholesterol Drugs
7. Researchers Learn How Nature Produces Cholesterol-Lowering Lovastatin
8. New Insights About Good Cholesterol
9. New Gene May Play Important Role In Regulating HDL, The Good Cholesterol
10. Chinese Condiment Cuts Blood Cholesterol
11. Blue-Green Algae Has Dual Cholesterol Lowering Abilities

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2020)... ... June 25, 2020 , ... ... biopharmaceutical R&D, today announced that it has entered into a multi-year contract ... (Multiclonics®), to support their translational and clinical research strategy to discover and ...
(Date:6/25/2020)... ... June 24, 2020 , ... ... software and software-driven clinical data services that accelerate drug development, is collaborating with ... an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is the first ...
(Date:6/23/2020)... , ... June 23, 2020 , ... ... sustainable healthcare, and Renovagen Ltd, a UK supplier and manufacturer of innovative portable ... support testing operations in the fight against the COVID-19 pandemic in Zambia. , ...
Breaking Biology News(10 mins):
(Date:6/11/2020)... ... June 09, 2020 , ... TRX Systems, developer of ... Solution, a highly accurate, contact tracing solution for identification of employees who ... a core disease control measure, is a key strategy for preventing further spread ...
(Date:6/3/2020)... ... June 03, 2020 , ... Thought ... of biofeedback. In the next installment, Dr. Inna Khazan will discuss the benefits ... to bring their attention to the feelings, thoughts, and emotions they are having ...
(Date:5/30/2020)... ... 29, 2020 , ... Medrio, Inc., the leading provider of ... enabled Cytovale, Inc., a medical technology company dedicated to revolutionizing diagnostics for conditions ... patient in (FPI) in just seven days. The Cytovale technology will allow patients ...
(Date:5/28/2020)... ... May 28, 2020 , ... Genedata, the leading provider of ... Screener ® 17.0, the latest version of its enterprise software for the automated ... Genedata will host a webinar on June 10, 2020, detailing and demonstrating the ...
Breaking Biology Technology:
Cached News: