HOME >> BIOLOGY >> NEWS
Cholesterol Lowering Drugs Stall Disease Progression In People With Below-Average Blood Cholesterol Level

DALLAS, May 12 -- A drug used to reduce cholesterol levels in the blood can prevent atherosclerosis -- even in people with below-average blood cholesterol levels -- according to a report in today's Circulation: Journal of the American Heart Association.

Lowering blood cholesterol in people with high levels of this waxy substance reduces the progression of atherosclerosis -- the build-up of fats and biological debris in the tissue lining the inside of blood vessels. New Zealand scientists found that no matter how low a person's cholesterol reading is, lowering his or her cholesterol prevented further development of blood vessel deposits that block blood flow to the heart and cause a heart attack.

"We were able to demonstrate a profound effect on the atherosclerotic disease process," says lead author, Stephen MacMahon, Ph.D., associate professor of medicine at the University of Auckland. "These results suggest that cholesterol lowering is likely to reduce atherosclerotic progression in most people with coronary heart disease across a broad range of pretreatment cholesterol levels," Mac Mahon and his colleagues say in their journal report.

Of the 522 people in the study, 273 were assigned to take 40 milligrams daily of a cholesterol-lowering drug called pravastatin and 249 received a placebo (an inert substance). Both groups were put on low-fat diets. Participants' blood cholesterol readings ranged from 155 to 271 milligrams per deciliter (mg/dL) at the start of the study. Average levels were considered to be about 218 mg/dL; below-average was about 184 mg/dL; and above-average levels were about 253 mg/dL.

Each underwent an ultrasound B scan of one carotid artery, the major artery that feeds blood to the brain, before being randomly assigned to either the drug or placebo-treated group. The scan was repeated two and four years into the study. Ultrasound
'"/>

Contact: Carole Bullock
caroleb@amhrt.org
214-706-1279
American Heart Association
11-May-1998


Page: 1 2 3

Related biology news :

1. Cholesterol lowering drug effective in treating most common form of multiple sclerosis
2. Cholesterol-independent benefits of statins in cardiac hypertrophy
3. Cholesterol levels not necessarily indicative of cardiac health
4. Women With Low Cholesterol May Be At Risk For Depression And Anxiety
5. Structure Of HDL Cholesterol Determined
6. Discovery Of A Molecule That Controls Bile Acids May Lead To New Cholesterol Drugs
7. Researchers Learn How Nature Produces Cholesterol-Lowering Lovastatin
8. New Insights About Good Cholesterol
9. New Gene May Play Important Role In Regulating HDL, The Good Cholesterol
10. Chinese Condiment Cuts Blood Cholesterol
11. Blue-Green Algae Has Dual Cholesterol Lowering Abilities

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2020)... ... June 25, 2020 , ... ... for biopharmaceutical R&D, today announced that it has entered into a multi-year ... antibodies (Multiclonics®), to support their translational and clinical research strategy to discover ...
(Date:6/23/2020)... , ... June 22, 2020 , ... The field of ... ligand binding assays (LBA) have dominated this area. However, the use of mass spectrometry ... , This now necessitates the question “How do you choose which approach to use ...
(Date:6/19/2020)... ... June 18, 2020 , ... Join experts from ... Principal Scientist in a live webinar on Wednesday, July 8, 2020 at ... the way we genetically engineer new models. However, while modifying the genome may be ...
Breaking Biology News(10 mins):
(Date:6/23/2020)... ... June 22, 2020 , ... ... antagonist, DRP-104, will be presented June 22-24 during the American Association for Cancer ... and, the other profiles the potent, consistent single agent activity in KEAP1 mutant ...
(Date:6/19/2020)... ... 2020 , ... The Vitaspace project was founded by the famous ... prolong life and find a way (medicine or technology) that will help to preserve ... various scientists from all over the world, doctors, and all people who care. , ...
(Date:6/11/2020)... ... June 09, 2020 , ... PathSensors Inc., a Baltimore ... Innovation Research (SBIR) program funded by the National Institute of Food and Agriculture ... Field”. The project’s goal was to engineer and develop a field-deployable instrument for ...
(Date:6/11/2020)... (PRWEB) , ... June 09, 2020 , ... Reducing carbon ... the world. From the Paris Agreement to stock market dips, ways to reduce CO2 ... adding biofuels to their portfolio. Most of the biofuels being produced today are created ...
Breaking Biology Technology:
Cached News: