HOME >> BIOLOGY >> NEWS
Cholesterol Lowering Drugs Stall Disease Progression In People With Below-Average Blood Cholesterol Level

DALLAS, May 12 -- A drug used to reduce cholesterol levels in the blood can prevent atherosclerosis -- even in people with below-average blood cholesterol levels -- according to a report in today's Circulation: Journal of the American Heart Association.

Lowering blood cholesterol in people with high levels of this waxy substance reduces the progression of atherosclerosis -- the build-up of fats and biological debris in the tissue lining the inside of blood vessels. New Zealand scientists found that no matter how low a person's cholesterol reading is, lowering his or her cholesterol prevented further development of blood vessel deposits that block blood flow to the heart and cause a heart attack.

"We were able to demonstrate a profound effect on the atherosclerotic disease process," says lead author, Stephen MacMahon, Ph.D., associate professor of medicine at the University of Auckland. "These results suggest that cholesterol lowering is likely to reduce atherosclerotic progression in most people with coronary heart disease across a broad range of pretreatment cholesterol levels," Mac Mahon and his colleagues say in their journal report.

Of the 522 people in the study, 273 were assigned to take 40 milligrams daily of a cholesterol-lowering drug called pravastatin and 249 received a placebo (an inert substance). Both groups were put on low-fat diets. Participants' blood cholesterol readings ranged from 155 to 271 milligrams per deciliter (mg/dL) at the start of the study. Average levels were considered to be about 218 mg/dL; below-average was about 184 mg/dL; and above-average levels were about 253 mg/dL.

Each underwent an ultrasound B scan of one carotid artery, the major artery that feeds blood to the brain, before being randomly assigned to either the drug or placebo-treated group. The scan was repeated two and four years into the study. Ultrasound
'"/>

Contact: Carole Bullock
caroleb@amhrt.org
214-706-1279
American Heart Association
11-May-1998


Page: 1 2 3

Related biology news :

1. Cholesterol lowering drug effective in treating most common form of multiple sclerosis
2. Cholesterol-independent benefits of statins in cardiac hypertrophy
3. Cholesterol levels not necessarily indicative of cardiac health
4. Women With Low Cholesterol May Be At Risk For Depression And Anxiety
5. Structure Of HDL Cholesterol Determined
6. Discovery Of A Molecule That Controls Bile Acids May Lead To New Cholesterol Drugs
7. Researchers Learn How Nature Produces Cholesterol-Lowering Lovastatin
8. New Insights About Good Cholesterol
9. New Gene May Play Important Role In Regulating HDL, The Good Cholesterol
10. Chinese Condiment Cuts Blood Cholesterol
11. Blue-Green Algae Has Dual Cholesterol Lowering Abilities

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/14/2019)... ... January 14, 2019 , ... CellMax ... cancer cells in blood, will present new findings at the ASCO Gastrointestinal Cancer ... colorectal cancer. The results from this study show CellMax Life’s blood test, based ...
(Date:1/10/2019)... (PRWEB) , ... January 09, 2019 , ... Dr. Beanlands ... Heart Institute in Ottawa, Ontario, Canada. He is also Director of its National ... of Medicine, in the Department of Radiology, and in the Department of Cellular and ...
(Date:1/10/2019)... ... 2019 , ... A major goal for pharmaceutical companies has ... significantly more expensive in vivo studies in order to reduce costs and improve ... researchers have begun to adopt 3D cell culture models which have been shown ...
Breaking Biology News(10 mins):
(Date:12/20/2018)... ... December 20, 2018 , ... New Year’s brings reflection ... changes in regulations in the European Union (EU) on the horizon, Jim Kasic, president ... , “The transition to the EU Medical Device Regulation (MDR), digital health, and big ...
(Date:12/18/2018)... ... December 18, 2018 , ... Patients with early stages of breast cancer who ... post-treatment versus whole breast irradiation, a new study suggests. , Patients with early stage ... irradiation after removal of the cancerous tumor because there is a 30 to 40 ...
(Date:12/13/2018)... ... December 13, 2018 , ... Microbial Discovery Group LLC (MDG) ... been part of their strategic plan and an important milestone in increasing their ... opportunities for MDG within the $44 Billion human probiotic market. This plan is ...
(Date:12/5/2018)... (PRWEB) , ... December 04, ... ... an established North American full-service contract research organization (CRO), announced the acquisition ... transaction significantly strengthens ARG’s reach and experience in the management of clinical ...
Breaking Biology Technology:
Cached News: