HOME >> BIOLOGY >> NEWS
Cholestyramine shows protective effects for marine toxin poisoning

Investigators at NOAA's National Ocean Service have observed that a commonly used cholesterol-lowering drug provides protective effects to a toxin produced by microscopic marine algae. Drs. J.S. Ramsdell, R. Woofter, J. Colman, S. Dover and M.Y. Dechraoui Bottein. National Oceanic Atmospheric Administration. Charleston, S.C., describe their research at an American Society for Pharmacology & Experimental Therapeutics session at the Experimental Biology 2003 meeting in San Diego.

Blooms of these toxic marine algae, commonly called harmful algal blooms (HABs) are one of the most scientifically complex and economically significant coastal issues facing the nation today. In the past, only a few regions of the U.S. were affected by HABs, but now virtually every coastal state has reported major blooms. Economic losses associated with HABs may exceed $1 billion over the next several decades. HABs have direct and indirect impacts on fisheries resources, local coastal economies, as well as public health and perception. HABs can cause human illness and death, alter marine habitats, adversely impact fish and other marine organisms, as well as close many coastal businesses.

HABs produce some of the most potent toxins known to man. These toxins are primarily neurotoxins, causing symptoms ranging from numbness and tingling sensations to memory impairment to respiratory paralysis. At present, coastal areas with persistent HAB problems are monitored for toxic algae in coordination with testing of seafood products. In the near future, forecasting of harmful algal blooms and new biomonitoring and therapeutic methods are anticipated to provide advanced warning capabilities, diagnostics and treatments. Cholestyramine, a commonly used cholesterol-lowering drug retained in the digestive tract, blocks re-absorption of cholesterol and related molecules. Cholestyramine is reported to provide protective effects following exposure of laboratory rats to fungal toxins a
'"/>

Contact: Sarah Goodwin
eb3press@bellsouth.net
770-270-0989
Federation of American Societies for Experimental Biology
13-Apr-2003


Page: 1 2

Related biology news :

1. New study shows hope for treating inhalant abuse
2. Chemical derived from vitamin-E shows early promise as cancer drug
3. Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
4. Trial shows which brain cancer patients benefit from temozolomide
5. New research shows plants can shuffle and paste gene pieces to generate genetic diversity
6. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
7. Simian virus 40 not associated with non-Hodgkin lymphoma, study shows
8. A probable cause for high blood pressure identified - shows links with diabetes
9. Blue marlin in gulf have high mercury levels, A&M study shows
10. New research shows air pollution can reduce childrens lung function
11. Pneumococcal vaccine reduces ear infections, pneumonia, new study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... April 11, 2017 NXT-ID, Inc. (NASDAQ: ... company, announces the appointment of independent Directors Mr. Robin ... its Board of Directors, furthering the company,s corporate governance and ... Gino Pereira ... look forward to their guidance and benefiting from their considerable ...
(Date:4/5/2017)... YORK , April 5, 2017 Today ... is announcing that the server component of the HYPR ... known for providing the end-to-end security architecture that empowers ... HYPR has already secured over 15 million ... makers including manufacturers of connected home product suites and ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... Lithuania, announced today that they have entered into a multiyear collaboration to identify ... CRISPR researchers with additional tools for gene editing across all applications. , Under ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the pharmaceutical and biotechnology industries to improve patient outcomes and quality of life, ... in analytical testing are being attributed to new regulatory requirements for all new ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... gene in its endogenous context, enabling overexpression experiments and avoiding the use of ... small RNA guides is transformative for performing systematic gain-of-function studies. , This ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... today it will be hosting a Webinar titled, “Pathology is going digital. Is ... , on digital pathology adoption best practices and how Proscia improves lab economics ...
Breaking Biology Technology:
Cached News: