HOME >> BIOLOGY >> NEWS
Cholestyramine shows protective effects for marine toxin poisoning

Investigators at NOAA's National Ocean Service have observed that a commonly used cholesterol-lowering drug provides protective effects to a toxin produced by microscopic marine algae. Drs. J.S. Ramsdell, R. Woofter, J. Colman, S. Dover and M.Y. Dechraoui Bottein. National Oceanic Atmospheric Administration. Charleston, S.C., describe their research at an American Society for Pharmacology & Experimental Therapeutics session at the Experimental Biology 2003 meeting in San Diego.

Blooms of these toxic marine algae, commonly called harmful algal blooms (HABs) are one of the most scientifically complex and economically significant coastal issues facing the nation today. In the past, only a few regions of the U.S. were affected by HABs, but now virtually every coastal state has reported major blooms. Economic losses associated with HABs may exceed $1 billion over the next several decades. HABs have direct and indirect impacts on fisheries resources, local coastal economies, as well as public health and perception. HABs can cause human illness and death, alter marine habitats, adversely impact fish and other marine organisms, as well as close many coastal businesses.

HABs produce some of the most potent toxins known to man. These toxins are primarily neurotoxins, causing symptoms ranging from numbness and tingling sensations to memory impairment to respiratory paralysis. At present, coastal areas with persistent HAB problems are monitored for toxic algae in coordination with testing of seafood products. In the near future, forecasting of harmful algal blooms and new biomonitoring and therapeutic methods are anticipated to provide advanced warning capabilities, diagnostics and treatments. Cholestyramine, a commonly used cholesterol-lowering drug retained in the digestive tract, blocks re-absorption of cholesterol and related molecules. Cholestyramine is reported to provide protective effects following exposure of laboratory rats to fungal toxins a
'"/>

Contact: Sarah Goodwin
eb3press@bellsouth.net
770-270-0989
Federation of American Societies for Experimental Biology
13-Apr-2003


Page: 1 2

Related biology news :

1. New study shows hope for treating inhalant abuse
2. Chemical derived from vitamin-E shows early promise as cancer drug
3. Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
4. Trial shows which brain cancer patients benefit from temozolomide
5. New research shows plants can shuffle and paste gene pieces to generate genetic diversity
6. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
7. Simian virus 40 not associated with non-Hodgkin lymphoma, study shows
8. A probable cause for high blood pressure identified - shows links with diabetes
9. Blue marlin in gulf have high mercury levels, A&M study shows
10. New research shows air pollution can reduce childrens lung function
11. Pneumococcal vaccine reduces ear infections, pneumonia, new study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2018)... ... August 21, 2018 , ... Whether it ... Labs is dedicated to offering customers a successful experience. When browsing the ... seamless transition between products, with relevant details such as technical manuals, application notes, ...
(Date:8/17/2018)... ... August 16, 2018 , ... Cryo-Cell ... cord blood bank to separate and store stem cells in 1992, announced that ... Sheehy, M.D. M.A. C.F.A., Founder and Managing Partner IsZo Capital, have joined the ...
(Date:8/14/2018)... ... August 13, 2018 , ... Quantification in body fluids like ... in the body as well as capturing drugs and their metabolites, in addition ... , By performing Nuclear Magnetic Resonance (MNR) on body fluid samples, the ...
Breaking Biology News(10 mins):
(Date:9/13/2018)... ... September 13, 2018 , ... Asymmetrex’s director, James L. Sherley, ... gotten in medicine, if we didn’t have the means to measure the number of ... His answer, “Nowhere! And that is what’s holding up progress in stem cell medicine.” ...
(Date:9/12/2018)... , ... September 11, 2018 , ... ... to add flat sheet Forward Osmosis (FO) membranes from Fluid Technology Solutions (FTS ... manufactured by FTS H2O are constructed from cellulose triacetate (CTA) material. The highly ...
(Date:9/7/2018)... , ... September 06, 2018 , ... ... from September 25th-28th is a meeting of “The industry’s preeminent event on novel ... drug discovery scientists powerful tools to study these emerging targets in a quest ...
(Date:9/7/2018)... ... September 06, 2018 , ... Akadeum Life Sciences today announced it ... as an executive and leader of numerous biotech companies. , He most recently ... company acquired by Thompson Street Capital in St. Louis, MO. Prior to ISTO, ...
Breaking Biology Technology:
Cached News: