Cinderella's shoe holds 500 sequencing machines

Imagine sequencing DNA with a machine you can hold in your hand - a miniaturized device that works far more quickly than current machines and uses fewer resources, too. In the September issue of Genome Research, Dieter Schmalzing, Daniel Erlich, and colleagues (Whitehead Institute) turn imagination into reality, reporting the first successful sequencing of "real world" DNA samples with a microdevice fabricated from glass wafers.

Schmalzing and colleagues set the novel goal of using a microdevice to sequence "typical" human DNA samples, as prepared for the Human Genome Project. To make the device, they chemically etched glass wafers with long, microscopically thin channels no more than a hundredth of a centimeter wide and about twelve centimeters long. Using short side channels, the researchers injected tiny "plugs" of DNA, labeled with fluorescent dyes, at one end of the channels. They then applied an electric field to the device to separate and move the DNA strands down the length of the channels, over a fluorescence detector that identified the components of the DNA. The device accurately and rapidly sequenced DNA from human chromosome 17 and demonstrates a bright future for convenient, low-cost sequencing machines. Perhaps soon we can literally put a sequencer in every pot.


Contact: Peggy Calicchia
Cold Spring Harbor Laboratory

Page: 1

Related biology news :

1. Improving crops without genetic modification natural variation holds the key
2. Protein stops blood-vessel growth, holds promise as cancer therapy
3. Many scientists believe the dog genome holds information that will benefit human health
4. New environmental journalism website holds more than 700 articles in three languages
5. Study calls for end to age thresholds for prenatal genetic testing
6. InterAcademy panel holds general assembly in Mexico
7. Worlds largest scientific society holds regional meeting in Atlanta
8. Worlds largest scientific society holds regional meeting in Columbia, Mo.
9. Worlds largest scientific society holds regional meeting in Long Beach, Calif.
10. Protein holds promise as new diabetes drug target
11. Few microbiological differences in households using antibacterials

Post Your Comments:

(Date:6/19/2020)... ... June 18, 2020 , ... Join experts from Envigo ... in a live webinar on Wednesday, July 8, 2020 at 11am EDT ... we genetically engineer new models. However, while modifying the genome may be more straightforward, ...
(Date:6/11/2020)... , ... June 09, 2020 , ... Superior Controls, ... industrial automation and IT solutions for the life sciences industry, is pleased to announce ... Development working out of the company’s Seabrook, New Hampshire office. In his new ...
(Date:6/5/2020)... HOUSTON (PRWEB) , ... June 04, 2020 , ... Greffex, ... Bush to its Board of Directors. , “Neil understands the need for a global ... also President and CEO of Greffex. Mr. Bush will serve as an independent, director ...
Breaking Biology News(10 mins):
(Date:6/11/2020)... (PRWEB) , ... June 09, 2020 , ... ... of Phase I of a Small Business Innovation Research (SBIR) program funded by ... 21st Century: Rapid Toxin Detection in the Field”. The project’s goal was to ...
(Date:6/2/2020)... ... June 01, 2020 , ... As part ... positive change in the world, enterprise security solutions provider bitsIO donated time to ... working from home during self-quarantines and shelter-in-place orders, companies are increasingly concerned about ...
(Date:5/28/2020)... (PRWEB) , ... May 28, 2020 , ... The ... and security leaders as the 2020 winners of the Women in Biometrics Awards ... sponsors IDEMIA , Biometric Update and the SIA Women in ...
(Date:5/21/2020)... , ... May 19, 2020 , ... Eaton Square is ... addition of Popper and Company, a biotechnology and medical technology-focused strategy and M&A advisory ... grow in the United States, linking US and Asia Pacific healthcare innovators with capital ...
Breaking Biology Technology:
Cached News: