HOME >> BIOLOGY >> NEWS
Circulatory Device -- A Bridge To Recovery For Heart Failure?

DALLAS, June 16 -- The dying heart cells of individuals with heart failure were brought back to life with the help of a mechanical circulation device, report researchers in today's Circulation: Journal of the American Heart Association.

"These findings represent the first report of improved function in human heart cells, called myocytes, with any therapy," says the study's lead author Kenneth B. Margulies, M.D., associate professor of medicine and physiology at Temple University Cardiac Transplant Center, in Philadelphia, About 4.9 million Americans suffer from heart failure in which the heart pumps less blood than needed by the body. The result is difficult breathing and fluid retention causing swollen tissues. Heart failure is often progressive with worsening symptoms and gradual deterioration of heart function. Current therapies for heart failure include drugs -- which reduce the heart's workload to slow the progression of the disease -- and heart transplantation. However, heart cells can not regenerate and drugs do little to help injured heart cells recover pumping ability.

For patients with advanced heart failure who do not respond to medications, heart transplantation can be lifesaving. Due to relatively long waiting times for heart transplantation, some people awaiting a transplant can be kept alive only with a mechanical left ventricular assist device (LVAD) which takes over most of the pumping for the failing heart.

The researchers found that LVAD support reduced the workload of the failing left side of the heart (the ventricle) to such an extent that some heart muscle cells recovered their ability to contract and relax.

"Our findings demonstrate that LVAD supports the heart even in the most severely failing hearts and may promote improvement in heart function," says Margulies. "These results clearly demonstrate that failing myocytes can regain some degree of their previously normal function and are not irreversibly damaged." LVAD su
'"/>

Contact: Carole Bullock
caroleb@amhrt.org
214-706-1279
American Heart Association
15-Jun-1998


Page: 1 2

Related biology news :

1. Device that rapidly detects nerve agents named one of greatest army inventions for 2003
2. Tiny tango: Device sorts microscopic particles with speed and precision
3. Device detects, traps and deactivates airborne viruses and bacteria
4. Device liberates quadriplegic from ventilator
5. Growing Up On Their Own: Smart Plastics Organize Themselves Into Useful Optical Devices
6. New Rehabilitative Device Combines Form And Function For Children With Mobility Impairments
7. New Device Brightens Recycling Efforts
8. New Device To Alleviate Distress Caused By Tinnitus
9. University of Kentucky Neuroscientist Develops Unique Device For Treatment Of Brain Tumors
10. Penn Researchers Invent Worlds First Device To Rapidly Assess Lung Function
11. UPMC Reports On New Liver Assist Device

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... ... , ... Regenative Labs has received approval from the Centers for Medicare & ... first Wharton’s jelly allografts to be assigned a Q code and be approved for ... Wharton’s jelly allograft product to be recognized as a 361 HCT/P by CMS regulated ...
(Date:7/18/2020)... ... July 16, 2020 , ... A study has been published ... Neoasis™ active noise control device to attenuate typical noises in a simulated neonatal ... the alarm sounds from patient monitors, ventilators and other bedside devices that would ...
(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio Inc. http://www.altrubio.com ... a biologic for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European ... J Martin of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... FARMS, Mich. (PRWEB) , ... August 12, 2020 ... ... Consulting Group, Inc. (EMMA International), a global leader in FDA compliance consulting ... of the nation’s fastest-growing private companies. The list represents a unique look at ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... ... collection, today announced Jim Corrigan, President and CEO has been named one of ... broad cross-section of industry sectors, PharmaVoice 100 honorees are selected based on how ...
(Date:7/31/2020)... ... July 29, 2020 , ... R3 Stem Cell International is ... $3950. With 50 million stem cells total, patients may choose which extremities they would ... for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 International, umbilical cord tissue is ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, and magnetrons. ... drive one or two switches in a push-pull configuration; yielding fast fall time ...
Breaking Biology Technology:
Cached News: