HOME >> BIOLOGY >> NEWS
Cloning chip

A CHIP that will automatically create hundreds of cloned embryos at a time is being developed by a Californian biotech company, New Scientist has learned.

If it lives up to its promise, the chip should help make cloning cheap and easy enough for companies to mass-produce identical copies of the best milk or meat producing animals for farmers. It might even be used for cloning human embryos.

The chip automates the laborious process of nuclear transfer, the key step in cloning. At present it takes hours of painstaking work with a microscope to remove the nucleus of an egg cell and replace it by fusing the denucleated egg with another cell.

"If somebody's got something like that, obviously it would make everybody's life easier," says Tanja Dominko of Advanced Cell Technology, the Massachusetts company that caused a stir late last year when it announced that it had created cloned human embryos.

In animals, cloning is still very wasteful. At best, around half of cloned embryos develop to the point where they can be implanted, and only a tenth of these survive to birth. Often more than a hundred nuclear transfers must be carried out to create a single clone.

Scientists usually start with a batch of 150 eggs, and denucleate them one at a time before moving on to the next step. That means eggs can be left sitting around for several hours, a delay that may reduce success rates.

But the nuclear transfer array developed at Aegen Biosciences, by the company's founders Richard Kuo and Gregory Baxter, could handle hundreds or even thousands of eggs at once. Kuo says they can routinely denucleate 30 to 50 sea urchin eggs at a time. They plan to start testing cow eggs in the next few weeks.

The prototype is a thin silicon slice a few centimetres across etched with hundreds of tiny wells, one for each egg. The trick is to spin the chip in a centrifuge, forcing the eggs' dense nuclei through a small hole at the bottom of each well. About 9
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
30-Jan-2002


Page: 1 2 3

Related biology news :

1. Cloning pigs and drug discovery among hot topics
2. Cloning primates is turning out to be a real challenge
3. Cloning can turn back the developmental clock
4. Cloning reverses aging in cow cells, Scienceauthors say
5. Cloning reverses aging in cow cells, a milestone in medical research
6. First Reproducible Cloning Of Mammals From Adult Cells Reported In Nature
7. Human Cloning: Grappling With Reality Penn Bioethicist To Explore The Facts Behind The Hysteria
8. The Cloning of Humans On The Adoption Model: Penn Bioethicist Will Present A Model For Future Laws Involving Human Cloning
9. UNESCO Director-General Reaffirms That Human Cloning Is Contrary To Human Dignity
10. Human Cloning: International Bioethics Committee President Stresses Political And Moral Commitment

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2016)... SAN FRANCISCO , June 16, 2016 /PRNewswire/ ... Market size is expected to reach USD ... report by Grand View Research, Inc. Technological proliferation ... and banking applications are expected to drive the ... ) , The development of ...
(Date:6/7/2016)... 2016  Syngrafii Inc. and San Antonio Credit ... includes integrating Syngrafii,s patented LongPen™ eSignature "Wet" solution ... will result in greater convenience for SACU members ... maintaining existing document workflow and compliance requirements. ... Highlights: ...
(Date:6/2/2016)... 2, 2016 Perimeter Surveillance & ... Systems, Physical Infrastructure, Support & Other Service  ... offers comprehensive analysis of the global Border ... generate revenues of $17.98 billion in 2016. ... a leader in software and hardware technologies for advanced ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... June 23, 2016 Houston Methodist Willowbrook ... Cy-Fair Sports Association to serve as their official ... Houston Methodist Willowbrook will provide sponsorship support, athletic ... with association coaches, volunteers, athletes and families. ... Cy-Fair Sports Association and to bring Houston Methodist ...
(Date:6/23/2016)... June 23, 2016  The Prostate Cancer Foundation (PCF) is pleased ... and faster cures for prostate cancer. Members of the Class of 2016 were ... Read More About the Class of 2016 PCF Young ... ... ...
(Date:6/23/2016)... FRANCISCO , June 23, 2016   EpiBiome ... has secured $1 million in debt financing from Silicon ... ramp up automation and to advance its drug development ... its new facility. "SVB has been an ... beyond the services a traditional bank would provide," said ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the ... at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application ... team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our ...
Breaking Biology Technology:
Cached News: