HOME >> BIOLOGY >> NEWS
Columbia Biologists Match Odor Receptor To Odor; Research Uncovers How Sense Of Smell Works; First Aroma Scientists Detect Is That Of Meat

Research Uncovers Details of How Sense of Smell Works; First Aroma Scientists Detect Is That of Meat

Molecular biologists at Columbia University for the first time have linked a particular odor with the proteins in the human nose that detect it. They made their first match with the smell of meat.

The research, by a team of biologists led by Stuart Firestein, associate professor of biological sciences at Columbia, is reported in the Jan. 9 issue of the journal Science. It builds on work conducted at Columbia that discovered the receptors' proteins that stick out from nerve cells in the nasal cavity and connect to molecules floating in the air, setting in motion a cascade of reactions that create a perception of odor in the brain.

"I believe this experiment will prove to be a Rosetta stone for olfaction, in that we can now begin to match odorants to receptors and decode this elusive sense," said Darcy Kelley, professor of biological sciences at Columbia, in an interview.

Researchers sprayed 74 individual scents, one at a time, over rat nerve cells that contained a particular odor receptor they had inserted in the cells. The first odor they matched to a receptor was that of octanal, which to humans smells like meat.

Linda Buck, a neuroscientist at Harvard Medical School, and Richard Axel, Higgins Professor of Biochemistry and Molecular Biophysics at Columbia's College of Physicians & Surgeons, in 1991 discovered both the family of transmembrane proteins that they believed to be odor receptors and some of the genes that code for those proteins. They found nearly 1,000 receptors, which in the human body number second only to the receptors in the immune system. Yet researchers had been unable to pair any single receptor or group of receptors with any particular odor until Professor Firestein's team reported their results.

If humans can make 1,000 odor receptors,
'"/>

Contact: Bob Nelson, Office of Public Affairs
rjn2@columbia.edu
(212) 854-6580
Columbia University
8-Jan-1998


Page: 1 2 3 4

Related biology news :

1. Columbia research to examine gene influence on severity of peridontal disease, therapy response
2. Columbia, Stony Brook, Guidant to develop biological pacemaker based on gene & cell therapies
3. Worlds largest scientific society holds regional meeting in Columbia, Mo.
4. New Columbia Genomic Center of Excellence aims to speed genetic targeting of medicines
5. Columbia offers new ecology program in Dominican Republic
6. Columbia professor receives 2003 National Golden Apple for Teaching Excellence
7. Columbia investigators win 2003 Gairdner International Award for research
8. Gene newly identified by Columbia researchers may improve hair removal
9. Years of research, thought lead geologist to propose new supercontinent Columbia
10. Columbia team finds treatment that corrects cellular defect at the root of heart failure
11. ESA Corporate Award winner 2001: Weyerhaeuser Company Limited British Columbia Coastal Forest Project Team

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/17/2017)... Florida , April 17, 2017 NXT-ID, ... technology company, announces the filing of its 2016 Annual Report on ... and Exchange Commission. ... on Form 10-K is available in the Investor Relations section of ... as on the SEC,s website at http://www.sec.gov . ...
(Date:4/13/2017)... 2017 According to a new market research report ... Identity Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region ... expected to grow from USD 14.30 Billion in 2017 to USD 31.75 ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... DUBLIN , Apr. 11, 2017 Research ... Tracking Market 2017-2021" report to their offering. ... The global eye tracking market to grow at ... The report, Global Eye Tracking Market 2017-2021, has been prepared based ... report covers the market landscape and its growth prospects over the ...
Breaking Biology News(10 mins):
(Date:7/17/2017)... N.J. (PRWEB) , ... July 17, 2017 , ... ... laboratory equipment and analytical instruments announced the launch of its new line of ... heavy-duty orbital shaker models (both analog and digital) for laboratory applications. These ...
(Date:7/17/2017)... ... , ... Panitch Schwarze Belisario & Nadel intellectual ... Innovation Group) annual meeting in China. , This year’s meeting, held June 9-10 ... a rapidly developing highly personalized anti-cancer technology that involves removing some of a ...
(Date:7/17/2017)... ... July 17, 2017 , ... ... innovation strategy. A website (openinnovation.pioneer.com) dedicated to connecting third-party innovators with ... trait discovery, plant breeding, enabling technologies, biologicals and digital solutions. , “DuPont Pioneer ...
(Date:7/16/2017)... (PRWEB) , ... July 16, 2017 , ... ... equipment and analytical instruments announced the launch of its new line of Extreme ... ideal for applications that require CO2 and humidity for optimal cell growth such ...
Breaking Biology Technology:
Cached News: