HOME >> BIOLOGY >> NEWS
Columbia Researchers Identify Gene For Inherited Baldness

New York, NY Jan. 26, 1998-- Researchers at Columbia University College of Physicians & Surgeons have discovered the first human gene associated with hair loss. The new gene, called hairless, is linked to a severe form of inherited baldness and may be the trigger that turns on the entire human hair cycle. The discovery could lead to a better understanding of the hair cycle and, eventually, more effective treatments for various forms of hair loss.

The research, reported in the Jan. 30 issue of Science, suggests that the gene initiates a cascade of events that stimulate hair growth. Each step along this pathway may provide new clues for male pattern baldness and other forms of hair loss, or alopecia.

"The discovery of this new gene gives us endless possibilities that may allow us to effectively treat hair loss and possibly baldness within the next five years," says principal investigator Angela M. Christiano, Ph.D., Herbert Irving Assistant Professor of Dermatology at Columbia-Presbyterian. "It is now within our reach to design ways to grow hair, remove hair, even dye hair genetically and -- best yet -- this can all be accomplished topically, reducing possible side effects."

Dr. Christiano's team noticed striking similarities between hairless mice that have been used in dermatology research for nearly 50 years and a rare genetic form of balding called alopecia universalis that involves hair loss over the entire body. The researchers relied on genetic information from families affected by the disorder in a village in Pakistan. By comparing the known mouse gene with human chromosomes, the team identified the first healthy trigger gene for hair growth and the mutation that causes this type of alopecia.

The several forms of alopecia represent a disruption in the cycle of human hair growth. The most common type of hair loss, known as androgenetic alopecia, or male pattern baldness, is believ
'"/>

Contact: Carolyn Conway
cc328@columbia.edu
212-305-3900
Columbia University Medical Center
29-Jan-1998


Page: 1 2

Related biology news :

1. Columbia research to examine gene influence on severity of peridontal disease, therapy response
2. Columbia, Stony Brook, Guidant to develop biological pacemaker based on gene & cell therapies
3. Worlds largest scientific society holds regional meeting in Columbia, Mo.
4. New Columbia Genomic Center of Excellence aims to speed genetic targeting of medicines
5. Columbia offers new ecology program in Dominican Republic
6. Columbia professor receives 2003 National Golden Apple for Teaching Excellence
7. Columbia investigators win 2003 Gairdner International Award for research
8. Gene newly identified by Columbia researchers may improve hair removal
9. Years of research, thought lead geologist to propose new supercontinent Columbia
10. Columbia team finds treatment that corrects cellular defect at the root of heart failure
11. ESA Corporate Award winner 2001: Weyerhaeuser Company Limited British Columbia Coastal Forest Project Team

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/18/2019)... LONG BEACH, Calif. (PRWEB) , ... June 18, ... ... provider of multi-GPU deep learning cloud solutions, today introduced Data Science Workstations-as-a-Service as ... data science workstation hardware from BOXX Technologies, Cirrascale Data Science Workstations feature NVIDIA® ...
(Date:6/14/2019)... ... , ... Molecular diagnostics segment is the fastest-growing segment within the global IVD ... segments that are expected to drive the growth are infectious diseases, cancer, and transplant ... Kalorama’s The World Molecular Diagnostics Market, 8th Edition . , The discovery of ...
(Date:6/11/2019)... ... June 12, 2019 , ... With a rapidly growing ... leverage the Geneious Biologics platform as a premium hub for bioinformatics and computer ... says: “The Geneious team has done an excellent job accommodating our specific data, ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... ... May 30, 2019 , ... A study released ... delivery system for the sustained release of human placental stem cell (HPSC)-derived conditioned ... able to deliver CM into the injured kidney, where it helped restore function ...
(Date:5/14/2019)... ... May 13, 2019 , ... Leak Detection ... for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries’ is excited to ... aims to improve LDA’s ability to communicate directly with the marketplace; serving as ...
(Date:5/4/2019)... , ... May 03, 2019 , ... ... release of the Diopsys® ffERG/Photopic Negative Response vision test, a new ... By 2050, it is estimated that 6.3 million Americans will have glaucoma, with ...
(Date:5/2/2019)... ... May 02, 2019 , ... Boston Robotic ... Boston area. Gone are the days of painful hair transplant procedures. Boston Robotic ... System is the only robotic intelligent solution to offer a minimally invasive procedure. ...
Breaking Biology Technology:
Cached News: