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Common thyroid cancer gene mutation found

creened for the BRAF mutation in other cancers and thyroid tumors. They found a small percentage in lung and head and neck cancers. Six out of nine (66 percent) thyroid cancer cell lines tested positive for the BRAF mutation. No mutations were found in biopsies from 20 benign thyroid conditions and other types of thyroid cancer such as follicular, medullary and Hhrthle cell. A research team at the Wellcome Trust Sanger Institute recently found the same mutation in the BRAF gene in approximately 80 percent of melanomas and some colon cancers.

Thyroid cancer affects 22,000 Americans each year and makes up about half of all head and neck cancers. The thyroid gland essentially impacts all cells of the body by regulating metabolism, chemical balance, and hormone production.


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Contact: Valerie Matthews Mehl
mehlva@jhmi.edu
410-955-1287
Johns Hopkins Medical Institutions
15-Apr-2003


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