HOME >> BIOLOGY >> NEWS
Common treatment for depression is safe and effective for Alzheimer's patients

Researchers at Johns Hopkins have shown that a drug, Zoloft, commonly used for depression, also improves quality of life and alleviates disruption in daily activities for the one-quarter of Alzheimer's patients who also suffer from major depression. However, the drug did not improve patients' cognitive abilities, such as thinking, remembering and learning, which are often impaired in Alzheimer's disease patients.

"Depression in Alzheimer's patients, and even Alzheimer's disease itself, often goes undiagnosed, in part because doctors feel they have little to offer in the form of treatment. This study shows that a simple treatment for depression improves the quality of life and seems to slow the functional decline of Alzheimer's disease," says Constantine Lyketsos, M.D., professor of psychiatry and behavioral sciences at Johns Hopkins and lead author of the report appearing in the July 2003 issue of the Archives of General Psychiatry.

The drug, called sertraline hydrochloride or Zoloft, is a common treatment for psychiatric diseases such as major depression, obsessive compulsive disorder and panic disorder.

Major depression affects 25 percent of patients with Alzheimer's disease, and when combined with the cognitive impairment of Alzheimer's, is extremely disabling and can lead to death or suicide, says Lyketsos.

"This simple and safe treatment for depression has tremendous potential for improving the quality of life for both Alzheimer's patients and their caregivers," said Lyketsos.

The study included adult participants with both Alzheimer's disease and major depression. All patients and their caregivers were educated about the illnesses and received encouragement and emotional support throughout the study. All patients were rated on a standardized depression scale and given a single placebo pill daily for one week in order to identify those with transient or temporary depression. Those patients with a drop of 30 per
'"/>

Contact: Trent Stockton
tstockt1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
23-Jul-2003


Page: 1 2

Related biology news :

1. Common cold virus can cause polio in mice when injected into muscles
2. Common call for action on European Research Council (ERC)
3. Common therapy for HIV associated with cervical abnormality regression
4. Common chemicals morphing into potential toxins in Arctic
5. Common worm provides insights into salmonella virulence
6. Common virus may contribute to uncommon bone disease in children
7. Common airborne substance makes asthmatics more sensitive to house dust mites: study
8. Common genetic damages in non-dividing cells lead to the creation of mutant proteins
9. Common nutrients fed to pregnant mice altered their offsprings coat color
10. Common gene variant increases risk of atherosclerosis
11. Common thyroid cancer gene mutation found

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/13/2019)... , ... June 13, 2019 , ... KICVentures ... Spine & The Spine, Orthopedic and Pain Management-Driven ASC Conference in Chicago on Thursday, ... Resorts 323 E. Wacker Dr. Chicago, IL in the 3rd floor Ticino Hospitality room ...
(Date:6/6/2019)... ... June 05, 2019 , ... ... a new network station and service center in Mexico City, Mexico. Mexico is ... world — with more than $1.75 billion in pharmaceutical exports since 2015. The ...
(Date:6/4/2019)... ... June 04, 2019 , ... ... for salient features of seizure risk signals, usually based on variations of amplitude, ... remains the only acceptable diagnostic methodology due to the complexity and variability of ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... ... 30, 2019 , ... A study released today in STEM ... the sustained release of human placental stem cell (HPSC)-derived conditioned medium (CM) to ... CM into the injured kidney, where it helped restore function and regenerate injured ...
(Date:5/15/2019)... ... May 16, 2019 , ... ... As a result, food and beverage products rely on these ingredients to create ... natural sounding label declarations. This paradigm shift triggers food formulators to seek out ...
(Date:5/7/2019)... ... May 06, 2019 , ... "The new Liquid Nitrogen Best ... being asked to store cellular products being used in adoptive therapy research ... world leaders, who have shared their expertise in building and managing facilities to ...
(Date:5/2/2019)... ... April 30, 2019 , ... The centuries old practice of brewing beer ... local craft breweries, and even home brewing clubs scattered across the nation. , ... that when mastered can produce a superb product. Students at South Dakota School ...
Breaking Biology Technology:
Cached News: