HOME >> BIOLOGY >> NEWS
Common treatment for depression is safe and effective for Alzheimer's patients

Researchers at Johns Hopkins have shown that a drug, Zoloft, commonly used for depression, also improves quality of life and alleviates disruption in daily activities for the one-quarter of Alzheimer's patients who also suffer from major depression. However, the drug did not improve patients' cognitive abilities, such as thinking, remembering and learning, which are often impaired in Alzheimer's disease patients.

"Depression in Alzheimer's patients, and even Alzheimer's disease itself, often goes undiagnosed, in part because doctors feel they have little to offer in the form of treatment. This study shows that a simple treatment for depression improves the quality of life and seems to slow the functional decline of Alzheimer's disease," says Constantine Lyketsos, M.D., professor of psychiatry and behavioral sciences at Johns Hopkins and lead author of the report appearing in the July 2003 issue of the Archives of General Psychiatry.

The drug, called sertraline hydrochloride or Zoloft, is a common treatment for psychiatric diseases such as major depression, obsessive compulsive disorder and panic disorder.

Major depression affects 25 percent of patients with Alzheimer's disease, and when combined with the cognitive impairment of Alzheimer's, is extremely disabling and can lead to death or suicide, says Lyketsos.

"This simple and safe treatment for depression has tremendous potential for improving the quality of life for both Alzheimer's patients and their caregivers," said Lyketsos.

The study included adult participants with both Alzheimer's disease and major depression. All patients and their caregivers were educated about the illnesses and received encouragement and emotional support throughout the study. All patients were rated on a standardized depression scale and given a single placebo pill daily for one week in order to identify those with transient or temporary depression. Those patients with a drop of 30 per
'"/>

Contact: Trent Stockton
tstockt1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
23-Jul-2003


Page: 1 2

Related biology news :

1. Common cold virus can cause polio in mice when injected into muscles
2. Common call for action on European Research Council (ERC)
3. Common therapy for HIV associated with cervical abnormality regression
4. Common chemicals morphing into potential toxins in Arctic
5. Common worm provides insights into salmonella virulence
6. Common virus may contribute to uncommon bone disease in children
7. Common airborne substance makes asthmatics more sensitive to house dust mites: study
8. Common genetic damages in non-dividing cells lead to the creation of mutant proteins
9. Common nutrients fed to pregnant mice altered their offsprings coat color
10. Common gene variant increases risk of atherosclerosis
11. Common thyroid cancer gene mutation found

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... ... August 13, 2019 , ... ... of Molecular Pathology, Institute of Cancer Research (ICR) in a live webinar ... about the process of biomarker and companion diagnostic development including machine learning approaches ...
(Date:8/6/2019)... ... August 05, 2019 , ... Keck Graduate Institute (KGI) President ... Pharmacy and Health Sciences (SPHS). , “Dean Zdanowicz is highly regarded as an innovative ... Jim Widergren. “He is a great choice to build on the success of the ...
(Date:8/1/2019)... ... ... The GENSPEED platform is a compact, fast and simple system to enable ... 100 units deployed in the field for multiple applications. “Beyond the creation of ... give us a foothold in the USA to better support other nascent test development ...
Breaking Biology News(10 mins):
(Date:7/9/2019)... DES MOINES, Iowa (PRWEB) , ... July 08, 2019 , ... ... in Des Moines, Iowa, the National Corn Growers Association (NCGA) announced the ... unique technology to improve a product or process using field corn to produce biobased ...
(Date:7/2/2019)... ... July 02, 2019 , ... Leading Regenerative Veterinary Medicine company, ... Beasts Meet Biotech. The film focuses on regenerative veterinary medicine as a means ... was recently included in the Brentwood and Pacific Palisades International Film Festival ...
(Date:6/18/2019)... YORK and SOMERSET, N.J. (PRWEB) , ... June ... ... Catalent Biologics, today announced that they have entered into an agreement for production ... product candidates, IC-100 for the treatment of rhodopsin-mediated autosomal dominant retinitis pigmentosa (RHO-adRP) ...
(Date:6/12/2019)... ... June 12, 2019 , ... Leak ... instruments for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries, is excited ... The agreement will grant exclusive rights for Zillion to represent LDA in all ...
Breaking Biology Technology:
Cached News: