HOME >> BIOLOGY >> NEWS
Component of fly saliva makes promising Leishmaniasis vaccine

Researchers seeking to make a vaccine against a serious parasitic infection have discovered a dose of fly saliva might be just what the doctor ordered. Leishmaniasis, a disabling and sometimes deadly tropical illness, is caused by a parasite transmitted to people through the bite of a sand fly. In a report released today, scientists from the National Institute of Allergy and Infectious Diseases (NIAID) describe how a vaccine they developed against a component of sand fly saliva prevents leishmaniasis in mice.

Leishmaniasis, a major health problem in many tropical and desert climates, has resisted efforts to develop an effective vaccine. "Today's report describes a novel vaccine," says NIAID Director Anthony S. Fauci, M.D. "Rather than targeting the parasite, as is typical, our researchers produced a vaccine to the saliva of the insect that transmits the parasite. This approach could potentially be used to develop vaccines for other insect- or tick-borne diseases."

Leishmaniasis refers to a group of related diseases. Different species of the single-celled parasite Leishmania can cause flesh-eating nose, throat and mouth infections (mucosal leishmaniasis); painful skin lesions (cutaneous leishmaniasis); or fatal infestations of the internal organs (visceral leishmaniasis). An estimated 12 million people currently are affected by one or more of these diseases, most of whom live in South or Central America, Africa and the Middle East.

NIAID's Jos Ribeiro, M.D., Ph.D., an expert on the biochemistry of blood-feeding bugs, has spent more than 30 years studying how components of saliva not only help insects and ticks obtain their blood meals but also modulate the immune response. He and others have previously shown that laboratory animals immunized with sand fly saliva often resist infection when later bitten by a Leishmania-carrying insect, or challenged with parasites in the presence of sand fly saliva. In the new study reported August 6
'"/>

Contact: Sam Perdue
sp189u@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
6-Aug-2001


Page: 1 2 3

Related biology news :

1. Component in plastic bottles found to cause abnormal pregnancies in mice
2. Largest Study Of Twins Shows Delay In Language Acquisition Has Strong Genetic Component Among Children At Low End Of Developmental Scale
3. Ancient "Jumping DNA" May Have Evolved into Key Component of Human Immune System
4. Researchers Identify New Component Of Circadian Clock
5. Getting At The Components Of Mechanotransduction: Genes Required For Vertebrate Sensory Hair Cell Function Identified
6. Candidate Regulator Of The Temporal Component Of Neurotransmitter Release Identified
7. 3-D Structure Of HIV Components May Pave The Way For New Anti-AIDS Drugs
8. Scientists Identify Retrovirus-Like Components In Corn Genome
9. Component In Soy Products May Be Substitute For Estrogen Treatment
10. Bone, enamel, dentine, milk & saliva share gene family
11. Bat saliva drug and new MRI techniques offer hope for acute stroke treatment

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2017)... , March 29, 2017  higi, the health IT ... North America , today announced a ... the acquisition of EveryMove. The new investment and acquisition ... of tools to transform population health activities through the ... data. higi collects and secures data today ...
(Date:3/27/2017)... N.Y. , March 27, 2017  Catholic ... Information and Management Systems Society (HIMSS) Analytics for ... EMR Adoption Model sm . In addition, CHS ... of U.S. hospitals using an electronic medical record ... for its high level of EMR usage in ...
(Date:3/24/2017)... Research and Markets has announced the addition of the ... Forecast to 2025" report to their offering. ... The Global Biometric Vehicle Access System ... over the next decade to reach approximately $1,580 million by 2025. ... forecasts for all the given segments on global as well as ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... For the second ... a US2020 STEM Mentoring Award. Representatives of the FirstHand program travelled to Washington, ... from US2020. , US2020’s mission is to change the trajectory of STEM education ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... 13 prestigious awards honoring scientists who have made outstanding contributions to ... symposium during Pittcon 2018, the world’s leading conference and exposition for laboratory science, ...
(Date:10/9/2017)... Antonio, Texas (PRWEB) , ... ... ... new study published on October 5, 2017, in the medical journal, Epilepsia, ... equivalence with the gold standard, video EEG, in detecting generalized tonic-clonic seizures ...
(Date:10/6/2017)... ... October 06, 2017 , ... On Tuesday, October 24th, ... INSIGhT, the first-ever adaptive clinical trial for glioblastoma (GBM). The featured speaker will ... free and open to the public, but registration is required. , WHAT: ...
Breaking Biology Technology:
Cached News: