HOME >> BIOLOGY >> NEWS
Compound from yeast shows promise in protecting against anthrax

BOSTON, Aug. 22 -- A compound from baker's yeast, used to make bread rise, may one day help protect people against deadly anthrax infections, according to researchers.

In laboratory tests, the compound, called WGP Beta Glucan, significantly increased the survival rate of mice infected with lethal anthrax spores. Researchers believe the compound can be developed into a potent drug that has a similar effect on humans. Their findings were presented today at the 224th national meeting of the American Chemical Society, the world's largest scientific society.

WGP Beta Glucan is a patented form of beta 1,3-glucan, a polysaccharide derived from the cell wall of baker's yeast and other natural sources. Beta 1,3-glucan's potential health benefits, particularly its immune-enhancing properties, have been the subject of numerous scientific studies.

The current study represents the first demonstration that a specific form of beta 1,3-glucan can enhance the immune system's ability to kill anthrax spores, and that it can do so orally, says Gary R. Ostroff, Ph.D., vice president of research and development at Biopolymer Engineering Inc., in Eagan, Minn.

The study involved 80 mice, all of which were infected with a lethal dose of deadly anthrax spores. Of the 20 that received a placebo treatment, 30 to 50 percent survived. Of the 60 mice given beta glucan, 75 to 100 percent survived, the researcher said.

Although the mechanism of the glucan compound is not completely understood, it appears to work by binding to and strengthening macrophages, immune cells that are the first line of defense against bacterial infection. As a result, the cells fight harder against infection. In the case of anthrax, the fortified macrophage cells appear to kill the bacterial spores before they have a chance to germinate and spawn the deadly toxins that can quickly overwhelm a less-protected immune system, the researcher explained.

Studies are planned to
'"/>


22-Aug-2002


Page: 1 2

Related biology news :

1. Compounds prevent alcohols disruption of important developmental process
2. Compound identified in grapes may fight cancer and diabetes
3. Compounds rejuvenate rats, may aid humans
4. Compounds in garlic fight malaria and cancer
5. Compound that switches off appetite in mice discovered by Hopkins scientists
6. Compounds From Fruits, Vegetables And Grains Slow The Growth Of Human Tumor Cells
7. UF Researchers Show Common Compound Can Reduce Air Pollution
8. Columbia Researchers Synthesize Compound With Possible Link To MacularDegeneration; Work Is Critical To Pinpointing Causes Of Disease, Scientists Say
9. Harbor Branch Oceanographic Institution And Novartis Pharma AG Sign AgreementFor Licensing And Development Of Anti-Cancer Compound, Discodermolide
10. Johns Hopkins Scientists Designing Compounds To Fight Malaria
11. Two-Pronged Attack On Immune System Cells Engineered By HIV Gene vpr: Effects Markedly Reversed By Antisteroid Compound RU-486

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio ... findings of Neihulizumab, a biologic for the treatment of steroid-refractory acute graft-versus-host disease ... hemato-oncologist Dr. Paul J Martin of the Fred Hutchinson Cancer Research Center, this ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... biopharmaceutical R&D, today announced that it has entered into a multi-year contract ... (Multiclonics®), to support their translational and clinical research strategy to discover and ...
(Date:6/23/2020)... (PRWEB) , ... June 23, 2020 , ... ... supporting sustainable healthcare, and Renovagen Ltd, a UK supplier and manufacturer of innovative ... to support testing operations in the fight against the COVID-19 pandemic in Zambia. ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... G-CON ... of its new tagline, “BUILDING FOR LIFE.” The adoption of this taglines comes ... globe, requiring fast track capacity to provide patients with urgently needed vaccines and ...
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been touted as the ... the history of eSource, the reasons it did not take off as quickly as ... source, the industry is moving towards capturing data electronically for clinical trials and then ...
(Date:7/18/2020)... ... ... After research model surgery and catheter implantation, the long journey of catheter ... of a successful study, while protecting and accessing the catheter or device post-surgery is ... from Envigo in a live webinar on Wednesday, August 5, ...
(Date:7/10/2020)... (PRWEB) , ... July 08, 2020 , ... ... services and products, announces a significant expansion of laboratory operations through its ... for agencies implementing testing programs. , Bode-CARES provides a turnkey ...
Breaking Biology Technology:
Cached News: