HOME >> BIOLOGY >> NEWS
Compound that switches off appetite in mice discovered by Hopkins scientists

in the brain. "The usual response to excess food is a decreased appetite," he says, "C75 appears to trigger this response artificially, by regulating the pathway, decreasing NPY and, thus, lowering appetite."

The C75 work comes out of the team's 14-year exploration of the abnormal fat metabolism that exists in many cancer cells. "Breast, prostate and cancer cells, for example, make a lot of fat. They have, correspondingly, a lot of constructive enzymes such as FAS," says Kuhajda. C75 was one of the chemicals the researchers created to inhibit FAS and clarify what was happening. "But it had this side effect," he adds, "that the lab animals always lost a lot of weight."

"We badly need effective drugs for weight loss," he comments. "Obesity is a huge problem. We're hoping to explore the possibilities of this new pathway."


'"/>

Contact: Marjorie Centofanti
mcentofanti@jhmi.edu
410-955-8725
Johns Hopkins Medical Institutions
29-Jun-2000


Page: 1 2 3

Related biology news :

1. Compounds prevent alcohols disruption of important developmental process
2. Compound from yeast shows promise in protecting against anthrax
3. Compound identified in grapes may fight cancer and diabetes
4. Compounds rejuvenate rats, may aid humans
5. Compounds in garlic fight malaria and cancer
6. Compounds From Fruits, Vegetables And Grains Slow The Growth Of Human Tumor Cells
7. UF Researchers Show Common Compound Can Reduce Air Pollution
8. Columbia Researchers Synthesize Compound With Possible Link To MacularDegeneration; Work Is Critical To Pinpointing Causes Of Disease, Scientists Say
9. Harbor Branch Oceanographic Institution And Novartis Pharma AG Sign AgreementFor Licensing And Development Of Anti-Cancer Compound, Discodermolide
10. Johns Hopkins Scientists Designing Compounds To Fight Malaria
11. Two-Pronged Attack On Immune System Cells Engineered By HIV Gene vpr: Effects Markedly Reversed By Antisteroid Compound RU-486

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/31/2017)... 31, 2017  Spero Therapeutics, LLC, a biopharmaceutical ... treatment of bacterial infections, today announced it has ... from Pro Bono Bio Ltd (PBB) to bolster ... resistant forms of Gram-negative bacteria.   The assets acquired ... a PBB group company. "The acquisition ...
(Date:1/26/2017)... , Jan. 26, 2017  Crossmatch, a leading ... a new solution aimed at combatting fraud, waste and ... was introduced at the Action on Disaster Relief conference ... meeting point for UN agencies and foreign assistance organizations ... Fraud, waste and abuse are a largely unacknowledged problem ...
(Date:1/25/2017)... 2017 The Elements of Enterprise Information Security ... comprised of a comprehensive set of business processes ... digital identities and providing a secured and documented ... significant number of programs opted by enterprises to ... optimizing processes and changing policies. However, there are ...
Breaking Biology News(10 mins):
(Date:2/23/2017)... NEW YORK , Feb. 23, 2017 ... a leading digital health company, and Digital ... telemedicine and remote patient monitoring, announce they are ... DN Telehealth maximizes collaboration compatibility ... extending consultations beyond a physical clinical setting to ...
(Date:2/23/2017)... 23, 2017  In Atlanta, it seems everyone has a ... intertwine to create an expressive and dynamic community unlike any ... and contribute to it. With their newest ... seeks to carry on that tradition with a unique, ... salon is the newest of 13 nationwide locations, ...
(Date:2/23/2017)... ... 2017 , ... David Nolte, PhD accepted Purdue University’s 2016 ... Research Park of West Lafayette, Indiana. , The top commercialization award is ... success with, commercializing discoveries from Purdue research. “This award is truly an honor. ...
(Date:2/23/2017)... SAN DIEGO and SAN FRANCISCO ... , a privately-held regenerative medicine company, and Beyond Type ... living with type 1 diabetes, today announced a grant ... develop a functional cure for type 1 and other ... decade, ViaCyte has been developing innovative stem cell-derived cell ...
Breaking Biology Technology:
Cached News: