HOME >> BIOLOGY >> NEWS
Compound that switches off appetite in mice discovered by Hopkins scientists

in the brain. "The usual response to excess food is a decreased appetite," he says, "C75 appears to trigger this response artificially, by regulating the pathway, decreasing NPY and, thus, lowering appetite."

The C75 work comes out of the team's 14-year exploration of the abnormal fat metabolism that exists in many cancer cells. "Breast, prostate and cancer cells, for example, make a lot of fat. They have, correspondingly, a lot of constructive enzymes such as FAS," says Kuhajda. C75 was one of the chemicals the researchers created to inhibit FAS and clarify what was happening. "But it had this side effect," he adds, "that the lab animals always lost a lot of weight."

"We badly need effective drugs for weight loss," he comments. "Obesity is a huge problem. We're hoping to explore the possibilities of this new pathway."


'"/>

Contact: Marjorie Centofanti
mcentofanti@jhmi.edu
410-955-8725
Johns Hopkins Medical Institutions
29-Jun-2000


Page: 1 2 3

Related biology news :

1. Compounds prevent alcohols disruption of important developmental process
2. Compound from yeast shows promise in protecting against anthrax
3. Compound identified in grapes may fight cancer and diabetes
4. Compounds rejuvenate rats, may aid humans
5. Compounds in garlic fight malaria and cancer
6. Compounds From Fruits, Vegetables And Grains Slow The Growth Of Human Tumor Cells
7. UF Researchers Show Common Compound Can Reduce Air Pollution
8. Columbia Researchers Synthesize Compound With Possible Link To MacularDegeneration; Work Is Critical To Pinpointing Causes Of Disease, Scientists Say
9. Harbor Branch Oceanographic Institution And Novartis Pharma AG Sign AgreementFor Licensing And Development Of Anti-Cancer Compound, Discodermolide
10. Johns Hopkins Scientists Designing Compounds To Fight Malaria
11. Two-Pronged Attack On Immune System Cells Engineered By HIV Gene vpr: Effects Markedly Reversed By Antisteroid Compound RU-486

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/1/2016)... -- Today, the first day of American Heart Month, the ... first of its kind workplace health solution that leverages ... first application of Watson to ... Welltok will create a new offering that combines AHA,s ... on Welltok,s health optimization platform. The effort is intended ...
(Date:1/25/2016)... BELL, Pa. , Jan. 25, 2016   Unisys Corporation ... recognition system at John F. Kennedy (JFK) International Airport, ... Border Protection (CBP) identify imposters attempting to enter ... do not belong to them. pilot testing of ... out initially at three terminals at JFK during January 2016. ...
(Date:1/21/2016)... January 21, 2016 ... new market research report "Emotion Detection and Recognition Market by ... Tools (Facial Expression, Voice Recognition and Others), Services, ... forecast to 2020", published by MarketsandMarkets, the global ... reach USD 22.65 Billion by 2020, at a ...
Breaking Biology News(10 mins):
(Date:2/5/2016)... N.C. , Feb. 5, 2016  In the ... role for a host of launch activities including the ... of this launch activity is especially high in the ... Best Practices and the Role of Medical ... help companies focused on oncology therapies find better ways ...
(Date:2/5/2016)... 5, 2016 Australian-US drug discovery and development company, ... appointment of a new Chairman, Mr John O,Connor , ... immediately. James Garner , has also been ... former Acting CEO, Mr Iain Ross , will resume ... --> James Garner , has also been formally appointed ...
(Date:2/4/2016)... RICHMOND, Calif. , Feb. 4, 2016  Sangamo ... therapeutic genome editing, announced today that Edward Lanphier ... an update on the progress of Sangamo,s ZFP Therapeutic ... company,s business strategy at 2:40 pm ET on Thursday, ... Annual Global Healthcare Conference. The conference is being ...
(Date:2/4/2016)... 4, 2016 Beike Biotechnology, the ... attended a ceremony in late 2015 to mark their ... in 2016. --> --> ... for Personalized Cell Therapy" was hosted by the Shenzhen ... both subsidiaries of Beike Biotechnology Co., Ltd. ...
Breaking Biology Technology:
Cached News: