Computer Program For Quicker, More Detailed Mapping

STANFORD--Researchers at the Stanford Human Genome Center have developed a powerful new computer program that can map thousands of genetic markers at once. Using this program, called Mapper, scientists have obtained one of the most accurate views yet of the human genome as a whole.

"These maps have better resolution in local areas than the other available whole genome maps," said Dr. David Cox, professor of genetics and co-director of the Stanford Human Genome Center. "The others can tell you what block the house is on, but we can give the exact address."

Mapper produces high-quality genetic maps that will dramatically advance the efforts of the Human Genome Project, whose goal is to map and sequence the genetic blueprint that contains all of the instructions about how to make a human body, said Richard Myers, professor of genetics and director of the Stanford Human Genome Center.

"Previously, it would take months for us to build a map," said Myers. "Now we can rebuild it every day, including new information as it is gathered. Our maps are now much more accurate because we can map everything at once."

The Stanford team that developed Mapper will present the new method, this week, along with the maps it has generated, at the Genome Mapping and Sequencing meeting at Cold Spring Harbor, N.Y., May 8-12.

To get an idea of the challenge confronting gene mappers, imagine constructing a map of the world knowing only that Palo Alto is close to San Francisco, Paris and Frankfurt are both in Europe, and Johannesburg and Nairobi are on the same continent.

Gene mappers use short, distinctive genetic markers found in DNA as signposts in the human genome. Markers that are close together remain on the same piece of DNA when scientists cut the long strands into small pieces. Using statistics to count how often particular pairs of markers remain together, computers can measure the distances between them and can determine their

Contact: Mike Goodkind
Stanford University Medical Center

Page: 1 2 3

Related biology news :

1. Computer scientists at UH developing nurturing computers
2. Computer models expose humans as main cause of caribou decline
3. Computer database being developed at Temple will allow for better inventory of chemicals
4. Computer imaging of Archeopteryx skull suggests this dinosaur-bird link could fly
5. Computer model shows increased US threat from soybean rust
6. 20 May AAAS lecture: Computers that Respond to Human Emotion
7. Computer modeling targets epidemics, bioterror
8. Computer method identifies potentially active enzymes
9. Computer scientists develop tool for mining genomic data
10. Computer model offers new tool to probe Woburn toxic waste site
11. Computer models forecast sharp increase in temperature if heat-trapping emissions continue to rise

Post Your Comments:

(Date:8/21/2020)... ... August 19, 2020 , ... The 19th ... life science, data science, informatics and IT leaders goes VIRTUAL and announces its ... uncertainty and change, Bio-IT takes the leadership role of keeping our life science ...
(Date:8/12/2020)... SEATTLE (PRWEB) , ... August 12, 2020 , ... ... tracking and monitoring systems that are ideal for public health agencies of all ... containing contagious diseases and helping at-risk individuals find appropriate health care, Mosio helps ...
(Date:8/5/2020)... ... 05, 2020 , ... Regenative Labs has received approval from the Centers for ... them the first Wharton’s jelly allografts to be assigned a Q code and be ... the first Wharton’s jelly allograft product to be recognized as a 361 HCT/P by ...
Breaking Biology News(10 mins):
(Date:7/1/2020)... ... June 29, 2020 , ... The Interlocal Purchasing ... to its membership, recently named BioFit Engineered Products an Awarded Vendor. ... purchase ergonomic seating, cafeteria tables, book trucks and carts at discounted pricing without ...
(Date:6/28/2020)... ... 25, 2020 , ... The Indoor Lab, a leading provider of sensor solutions ... all types to ensure cleanliness, distancing and occupancy with its patent pending WipeAway™ technology ... business will provide a health performance index system that scores all aspects of compliance ...
(Date:6/28/2020)... Conn. (PRWEB) , ... June 25, 2020 , ... ... formed to advance photodynamic therapy for treating cancer, today announced the company has ... York (“Roswell Park”). The agreement provides Lumeda globally exclusive rights to Roswell ...
(Date:6/23/2020)... ... 2020 , ... Kerafast Inc. , developers of an ... availability of the Delta-G-VSV Pseudotyping System for coronavirus research applications. The system, developed ... viral entry and COVID-19 vaccine effectiveness at just biosafety level 2 (BSL-2) containment. ...
Breaking Biology Technology:
Cached News: