HOME >> BIOLOGY >> NEWS
Computer generates comparative gene maps

ITHACA, N.Y. -- Comparing the genomes of two related species of a plant or animal often helps to locate important genes that have been identified in one species but not in another, and can provide clues about how both species evolved from a common ancestor. But making these "comparative gene maps" has been a slow, painstaking process, something biologists do by hand over weeks, months or years, using data painstakingly collected in "wet labs" and analyzed with software designed to interpret only one map at a time.

Now, Cornell University researchers have come up with a way to do the comparison step in a few hours on a computer. In early tests, a computer-generated comparison of the genomes of rice and maize (corn) closely matched a similar map made by hand, and even suggested some relationships that had not shown up in the handmade map.

Debra Goldberg, Cornell graduate student in applied mathematics, developed the new method in collaboration with Susan McCouch, Cornell professor of plant breeding, and Jon Kleinberg, Cornell assistant professor of computer science. Goldberg described their work at the Gene Order Dynamics, Comparative Maps and Multigene Families (DCAF) workshop held September in Sainte-Adèle, Quebec, and will present a later version at the Plant and Animal Genome IX conference in San Diego in January. Their paper, "Algorithms for Constructing Comparative Maps," appears in Comparative Genomics (David Sankoff and Joseph H. Nadeau, Eds., Kluwer Academic Publishers, 2000). A software implementation of the new method soon will be available to geneticists.

"The point of this isn't just to compare rice and corn, but to be able to do it with any two species," Goldberg says. "Ideally we'd like to be able to find new evolutionary pathways."

Every so often, as reproductive cells divide, genes and segments of chromosomes get shuffled around. One chromosome meets another and pieces of DNA are moved or swapped. If those particular c
'"/>

Contact: Bill Steele
ws21@cornell.edu
607-255-7164
Cornell University News Service
20-Dec-2000


Page: 1 2 3 4

Related biology news :

1. Computer scientists at UH developing nurturing computers
2. Computer models expose humans as main cause of caribou decline
3. Computer database being developed at Temple will allow for better inventory of chemicals
4. Computer imaging of Archeopteryx skull suggests this dinosaur-bird link could fly
5. Computer model shows increased US threat from soybean rust
6. 20 May AAAS lecture: Computers that Respond to Human Emotion
7. Computer modeling targets epidemics, bioterror
8. Computer method identifies potentially active enzymes
9. Computer scientists develop tool for mining genomic data
10. Computer model offers new tool to probe Woburn toxic waste site
11. Computer models forecast sharp increase in temperature if heat-trapping emissions continue to rise

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... March 24, 2017 The Controller General of Immigration ... Abdulla Algeen have received the prestigious international IAIR Award for ... Continue Reading ... ... Deputy Controller Abdulla Algeen (small picture on the right) have received the ...
(Date:3/23/2017)... DUBLIN , Mar. 23, 2017 Research ... Anti-Theft System Market Analysis & Trends - Industry Forecast to 2025" ... ... to grow at a CAGR of around 8.8% over the next ... This industry report analyzes the market estimates and forecasts for all ...
(Date:3/22/2017)... March 21, 2017 Vigilant Solutions , ... law enforcement agencies, announced today the appointment of retired ... of public safety business development. Mr. Sheridan ... experience, including a focus on the aviation transportation sector, ... recent position, Mr. Sheridan served as the Aviation Liaison ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... and RESEARCH TRIANGLE PARK, N.C. ... Corporation (NASDAQ: UTHR ) today announced that ... to $250 million of the company,s common stock. This ... through December 31, 2017. Purchases may be made in ... negotiated transactions from time to time as determined by ...
(Date:4/27/2017)... ... April 27, 2017 , ... This month ... (eConsent) solution that simplifies research studies, accelerates study startup, and improves participant engagement. ... Consent™ is the first and only IRB-integrated eConsent solution . , “Our ...
(Date:4/27/2017)... (PRWEB) , ... April 27, ... ... today announced a comprehensive rebrand and a name change to Fluence Analytics. ... industrial and laboratory monitoring of polymer and biopharmaceutical manufacturing processes and R&D ...
(Date:4/27/2017)... April 27, 2017  Kinexum, a distinguished resource for ... announces the appointment of Thomas C. Seoh ... Fleming, M.D., Kinexum founder, who becomes Executive Chairman and ... Kinexum clients. Thomas Seoh commented, ... Kinexum mission and lead the firm,s remarkable team of ...
Breaking Biology Technology:
Cached News: