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Congratulations, it's a soy!: Penn researchers take a long-term look at the safety of soy-based infant formula

(Philadelphia, PA) To understand whether hormone-like chemicals in soy products may influence sexual development in children, researchers at the University of Pennsylvania School of Medicine have revisited a study on soy-based infant formula begun over thirty years ago. Their results, published in this weeks Journal of the American Medical Association, reaffirm the safety of soy infant formula and offer evidence against the harmful effects of soy that have been presented in the popular media. According to their findings, soy formula does not appear to lead to any more health or reproductive problems than cow milk formula.

We have found that, in terms of sexual development, there is very little difference between children who, as infants, were fed cow milk formula and those fed soy formula, said Brian L. Strom, MD, MPH, director of the Penn Department of Biostatistics and Epidemiology. The biggest concern has been whether or not phytoestrogens in soy had a feminizing effect on children.

Strom is quick to add, however, that the idea is not entirely unfounded. Phytoestrogens, which occur naturally in soy, are analogous to the human female hormone estrogen. Infants fed soy formula receive relatively high doses of phytoestrogen during a time of life when they are rapidly growing. It comes as no surprise, then, that the possibility of altering a childs development had concerned some parents and scientists.

In this study, we interviewed young adults who had been part of feeding studies as infants, said Strom. We were looking for abnormalities in their adolescent and sexual development attributable to their early exposure to soy phytoestrogens.

This study has its roots in a landmark study at the University of Iowa, which first started looking at the effects of soy formula on infants beginning in 1965 and lasting until 1978. At the time, soy was still relatively new to the American diet. Then, as now, soy was seen as an excellent source of
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Contact: Greg Lester
lesterg@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
14-Aug-2001


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