HOME >> BIOLOGY >> NEWS
Could hibernators hold the key to improving organ preservation?

April 9, 2003 (San Diego, CA) -- Each day about 63 people receive an organ transplant, but another 16 people on the waiting list die because not enough organs are available. "Available" is the operative word in this shortage of transplantable organs.

A donor's gift may be available, but the transportation time to the sick patient, coupled with the period that an organ can be safely preserved without damage, may indicate that those on the waiting list are victims of logistics as well as availability.

Currently, organs such as the liver or pancreas can be stored for 36 hours, though damage occurs after a day. Hibernating mammals may provide new insights to extend storage times and improve the quality of cold-stored organs. Each winter, hibernators such as ground squirrels and marmots undergo periods of torpor in which body temperature and metabolic rate are only a fraction of normal levels, without damage to their organs. For weeks at a time, hibernators maintain a body temperature close to zero degrees Celsius, which is similar to that used for human organ preservation.

Researchers at the University of Wisconsin and the University of Colorado set out to study hibernating mammals as a model for organ tolerance to extended cold preservation. The researchers are Dr. Hannah Carey at the University of Wisconsin-Madison School of Veterinary Medicine, Dr. James Southard at the UW-Madison Medical School and Dr. Sandy Martin at the University of Colorado Health Sciences Center in Denver. Their findings are being presented at Experimental Biology 2003, a conference sponsored by the American Physiological Society, being held April 11-15, 2003 at the San Diego Convention Center, San Diego, CA.

Background

Previous studies from this research team suggest that livers from hibernating ground squirrels show superior tolerance to extended cold storage when compared to a non-hibernator, such as the rat. The tolerance in sum
'"/>

Contact: Donna Krupa
djkrupa1@aol.com
703-967-2751
American Physiological Society
9-Apr-2003


Page: 1 2 3

Related biology news :

1. Endometriosis: Could angiostatic therapy be the new treatment of the future?
2. Could mice hold the secret to longer life?
3. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
4. Could memory performance and spatial learning be genetically based?
5. Could a specific protein contribute to erectile dysfunction for the diabetic and obese?
6. Could diabetes treatments fight cancer?
7. Could rice be the source for a natural herbicide?
8. Could Bt transgenic crops have nutritionally favourable effects on insects?
9. Could one less cookie a day help the fight against fat?
10. Could an anti-marijuana compound hold the key to body weight and appetite control?
11. Study finds genetic aberrations linked to lung cancer; Could help in early diagnosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... KONG , March 30, 2017 The ... a system for three-dimensional (3D) fingerprint identification by adopting ground breaking ... into a new realm of speed and accuracy for use in ... at an affordable cost. ... ...
(Date:3/29/2017)... -- higi, the health IT company that operates the largest ... , today announced a Series B investment from BlueCross ... new investment and acquisition accelerates higi,s strategy to create ... health activities through the collection and workflow integration of ... and secures data today on behalf of over 36 ...
(Date:3/27/2017)... 2017  Catholic Health Services (CHS) has been ... (HIMSS) Analytics for achieving Stage 6 on the ... In addition, CHS previously earned a place in ... electronic medical record (EMR). "HIMSS Analytics ... EMR usage in an outpatient setting.  This recognition ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... any gene in its endogenous context, enabling overexpression experiments and avoiding the use ... with small RNA guides is transformative for performing systematic gain-of-function studies. , ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading provider ... nationwide oncology Clinical Nurse Educator (CNE) network, which will launch ... for communication among health care professionals to enhance the patient ... office staff, and other health care professionals to help women ... cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator ... osteosarcoma. SBT-100 is able to cross the cell membrane and bind intracellular STAT3 ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder and CEO of ... Rotary Club. The event entitled “Stem Cells and Their Regenerative Powers,” ... Dr. Harman, DVM, MPVM was joined by two human doctors: Peter B. Hanson, ...
Breaking Biology Technology:
Cached News: