HOME >> BIOLOGY >> NEWS
Could memory performance and spatial learning be genetically based?

February 4, 2004 BETHESDA, MD As the US population ages, there is an increasing effort to understand the underlying mechanisms that contribute to learning and memory. This effort could be of critical importance to scientists trying to decipher how the molecular genetic mechanisms of learning and memory are disrupted or impaired. The results of a new study provide evidence that individual differences in some cognitive functions may have a genetic basis.

A New Study

The authors of the study are Nelson Ruiz-Opazo, of the Section of Molecular Medicine, Boston University School of Medicine, Boston, MA, and John Tonkiss, from the Center for Behavioral Development and Mental Retardation, Boston University School of Medicine, Boston, MA. Their study, entitled "X-Linked Loci Influence Spatial Navigation Performance in Dahl Rats," now appears in the Articles in Press section of Physiological Genomics, one of one of 14 scientific journals published monthly by the American Physiological Society (APS) (www.the-aps.org).

Methodology

Dahl S/hsd (n=12) and Dahl R/hsd (n=12) male rats were obtained. Reciprocal mating of the parental strains (Dahl R female x Dahl S male and Dahl S female x Dahl R male) produced two types of F1 male hybrids: F1[RXS] (n=12) and F1[SXR] (n=11), respectively. A cohort was derived from brother-to-sister mating of F1 (R female x S male) hybrids to produce and F2 male segregation population (n=178). Behavioral testing was performed on parental, F1 and F2 cohorts at 12 weeks of age.

The Morris water maze (MWM) task was performed using a circular water maze and a computer tracking system. A circular platform was placed at the center of one of four imaginary quadrants and the water rendered opaque. Swim distance was used to evaluate performance.

  • In the hidden platform version of the maze task the platform was submerged below the water's surface and
    '"/>


  • Contact: Donna Krupa
    djkrupa1@aol.com
    703-527-7357
    American Physiological Society
    4-Feb-2004


    Page: 1 2 3

    Related biology news :

    1. Endometriosis: Could angiostatic therapy be the new treatment of the future?
    2. Could mice hold the secret to longer life?
    3. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
    4. Could a specific protein contribute to erectile dysfunction for the diabetic and obese?
    5. Could diabetes treatments fight cancer?
    6. Could rice be the source for a natural herbicide?
    7. Could hibernators hold the key to improving organ preservation?
    8. Could Bt transgenic crops have nutritionally favourable effects on insects?
    9. Could one less cookie a day help the fight against fat?
    10. Could an anti-marijuana compound hold the key to body weight and appetite control?
    11. Study finds genetic aberrations linked to lung cancer; Could help in early diagnosis

    Post Your Comments:
    (Date:3/31/2015)... YORK , March 31, 2015  Elephant Talk ... "Company"), a global provider of Software Defined Network Architecture ... today announced total revenue of approximately $20.4 million for ... a restated $19.5 million for the year ended December ... calendar 2014, the Company had completed its multi-year transition ...
    (Date:3/24/2015)... Markets ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ) has announced the addition of ... report to their offering. This report analyzes the ... the following Segments: Face Biometrics, and Voice Biometrics. The report provides ... Japan , Europe , ... Africa , and Latin America ...
    (Date:3/23/2015)... 2015  In the 2014 fiscal year, irs.gov recorded ... This figure accounts for a fraction of the estimated ... Report, exceeds $11 billion globally. The polygraph has traditionally ... has occurred. Investor Mark Saint Juste along ... Paolella partnered to administer the test in a ...
    Breaking Biology News(10 mins):Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3
    (Date:4/1/2015)... April 1, 2015 Synthetic Biologics, Inc. ... for serious infections and diseases, with a focus ... data supporting the development of SYN-004, the Company,s ... (IV) antibiotics within the gastrointestinal (GI) tract and ... for the prevention of C. difficile ...
    (Date:4/1/2015)... April 1, 2015  Spherix Incorporated (Nasdaq: ... the fostering and monetization of intellectual property, today ... held full service global investment bank specializing in ... industry note featuring Spherix. The report, ... Senior Analyst at Chardan, was published on March ...
    (Date:4/1/2015)... The concept of “spot reducing” areas is ... Founder of Fasciology, Ashley Black, says that even the idea ... of having to wait for the whole fat system to ... to fat cooling procedures, the only well known way ... which is a highly invasive procedure.” It is common knowledge ...
    (Date:4/1/2015)... National recruitment firm Slone Partners ... as Head of Sales at Optimal Medicine, an international ... , Allen brings over 20 years experience in healthcare ... of companies including Dell Services Healthcare, Medsphere Systems and ... perfect fit for accomplishing the goals Optimal Medicine had ...
    Breaking Biology Technology:Synthetic Biologics' SYN-004 Clinical Data for Protection of Microbiome Selected for Poster Presentation at American Society of Microbiology 2015 2Synthetic Biologics' SYN-004 Clinical Data for Protection of Microbiome Selected for Poster Presentation at American Society of Microbiology 2015 3Synthetic Biologics' SYN-004 Clinical Data for Protection of Microbiome Selected for Poster Presentation at American Society of Microbiology 2015 4Chardan Capital Issues Industry Note Covering Spherix 2Chardan Capital Issues Industry Note Covering Spherix 3Hybrid Health Guru, Ashley Black, announces that her invention The FasciaBlaster™ rivals the “fat cooling” procedures that reduce exercise and diet resistant fat pockets. 2Hybrid Health Guru, Ashley Black, announces that her invention The FasciaBlaster™ rivals the “fat cooling” procedures that reduce exercise and diet resistant fat pockets. 3Slone Partners Fills Head of Sales at Optimal Medicine 2
    Cached News: