HOME >> BIOLOGY >> NEWS
Could memory performance and spatial learning be genetically based?

February 4, 2004 BETHESDA, MD As the US population ages, there is an increasing effort to understand the underlying mechanisms that contribute to learning and memory. This effort could be of critical importance to scientists trying to decipher how the molecular genetic mechanisms of learning and memory are disrupted or impaired. The results of a new study provide evidence that individual differences in some cognitive functions may have a genetic basis.

A New Study

The authors of the study are Nelson Ruiz-Opazo, of the Section of Molecular Medicine, Boston University School of Medicine, Boston, MA, and John Tonkiss, from the Center for Behavioral Development and Mental Retardation, Boston University School of Medicine, Boston, MA. Their study, entitled "X-Linked Loci Influence Spatial Navigation Performance in Dahl Rats," now appears in the Articles in Press section of Physiological Genomics, one of one of 14 scientific journals published monthly by the American Physiological Society (APS) (www.the-aps.org).

Methodology

Dahl S/hsd (n=12) and Dahl R/hsd (n=12) male rats were obtained. Reciprocal mating of the parental strains (Dahl R female x Dahl S male and Dahl S female x Dahl R male) produced two types of F1 male hybrids: F1[RXS] (n=12) and F1[SXR] (n=11), respectively. A cohort was derived from brother-to-sister mating of F1 (R female x S male) hybrids to produce and F2 male segregation population (n=178). Behavioral testing was performed on parental, F1 and F2 cohorts at 12 weeks of age.

The Morris water maze (MWM) task was performed using a circular water maze and a computer tracking system. A circular platform was placed at the center of one of four imaginary quadrants and the water rendered opaque. Swim distance was used to evaluate performance.

  • In the hidden platform version of the maze task the platform was submerged below the water's surface and
    '"/>


  • Contact: Donna Krupa
    djkrupa1@aol.com
    703-527-7357
    American Physiological Society
    4-Feb-2004


    Page: 1 2 3

    Related biology news :

    1. Endometriosis: Could angiostatic therapy be the new treatment of the future?
    2. Could mice hold the secret to longer life?
    3. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
    4. Could a specific protein contribute to erectile dysfunction for the diabetic and obese?
    5. Could diabetes treatments fight cancer?
    6. Could rice be the source for a natural herbicide?
    7. Could hibernators hold the key to improving organ preservation?
    8. Could Bt transgenic crops have nutritionally favourable effects on insects?
    9. Could one less cookie a day help the fight against fat?
    10. Could an anti-marijuana compound hold the key to body weight and appetite control?
    11. Study finds genetic aberrations linked to lung cancer; Could help in early diagnosis

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:4/4/2017)... April 4, 2017   EyeLock LLC , a ... the United States Patent and Trademark Office (USPTO) has ... the linking of an iris image with a face ... represents the company,s 45 th issued patent. ... very timely given the multi-modal biometric capabilities that have ...
    (Date:3/30/2017)... YORK , March 30, 2017 Trends, ... type (physiological and behavioral), by technology (fingerprint, AFIS, iris ... voice recognition, and others), by end use industry (government ... and immigration, financial and banking, and others), and by ... Europe , Asia Pacific , ...
    (Date:3/24/2017)... The Controller General of Immigration from Maldives Mr. Mohamed ... received the prestigious international IAIR Award for the most innovative high security ... ... Maldives Immigration Controller General, ... picture on the right) have received the IAIR award for the "Most ...
    Breaking Biology News(10 mins):
    (Date:6/20/2017)... Pa. , June 20, 2017  Kibow Biotech ... pleased to announce the issuance of a new patent ... or hyperuricemia by the U.S. Patent and Trademark Office ... a winner of the Buzz of Bio award in ... is akin to developing non-drug approaches to chronic disease. ...
    (Date:6/19/2017)... NJ (PRWEB) , ... June 19, 2017 , ... ... innovative solutions for clinical development reported today that it is launching two new ... The company will be demonstrating new capabilities at the DIA 2017 Annual Meeting ...
    (Date:6/16/2017)... ... 2017 , ... CTNext , Connecticut’s go-to resource for entrepreneurial support, today ... at Chelsea Piers in Stamford. , Nine finalists, all of whom are Connecticut-based companies ... opportunity to secure $10,000 awards to help support business growth. The winners included:, ...
    (Date:6/15/2017)... (PRWEB) , ... June 15, 2017 , ... ... business director for DuPont Biofuels, will be speaking at Bloomberg’s 2017 Sustainable ... will join other leading environmental and sustainability officials on a panel titled “Developing ...
    Breaking Biology Technology:
    Cached News: