HOME >> BIOLOGY >> NEWS
Could memory performance and spatial learning be genetically based?

February 4, 2004 BETHESDA, MD As the US population ages, there is an increasing effort to understand the underlying mechanisms that contribute to learning and memory. This effort could be of critical importance to scientists trying to decipher how the molecular genetic mechanisms of learning and memory are disrupted or impaired. The results of a new study provide evidence that individual differences in some cognitive functions may have a genetic basis.

A New Study

The authors of the study are Nelson Ruiz-Opazo, of the Section of Molecular Medicine, Boston University School of Medicine, Boston, MA, and John Tonkiss, from the Center for Behavioral Development and Mental Retardation, Boston University School of Medicine, Boston, MA. Their study, entitled "X-Linked Loci Influence Spatial Navigation Performance in Dahl Rats," now appears in the Articles in Press section of Physiological Genomics, one of one of 14 scientific journals published monthly by the American Physiological Society (APS) (www.the-aps.org).

Methodology

Dahl S/hsd (n=12) and Dahl R/hsd (n=12) male rats were obtained. Reciprocal mating of the parental strains (Dahl R female x Dahl S male and Dahl S female x Dahl R male) produced two types of F1 male hybrids: F1[RXS] (n=12) and F1[SXR] (n=11), respectively. A cohort was derived from brother-to-sister mating of F1 (R female x S male) hybrids to produce and F2 male segregation population (n=178). Behavioral testing was performed on parental, F1 and F2 cohorts at 12 weeks of age.

The Morris water maze (MWM) task was performed using a circular water maze and a computer tracking system. A circular platform was placed at the center of one of four imaginary quadrants and the water rendered opaque. Swim distance was used to evaluate performance.

  • In the hidden platform version of the maze task the platform was submerged below the water's surface and
    '"/>


  • Contact: Donna Krupa
    djkrupa1@aol.com
    703-527-7357
    American Physiological Society
    4-Feb-2004


    Page: 1 2 3

    Related biology news :

    1. Endometriosis: Could angiostatic therapy be the new treatment of the future?
    2. Could mice hold the secret to longer life?
    3. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
    4. Could a specific protein contribute to erectile dysfunction for the diabetic and obese?
    5. Could diabetes treatments fight cancer?
    6. Could rice be the source for a natural herbicide?
    7. Could hibernators hold the key to improving organ preservation?
    8. Could Bt transgenic crops have nutritionally favourable effects on insects?
    9. Could one less cookie a day help the fight against fat?
    10. Could an anti-marijuana compound hold the key to body weight and appetite control?
    11. Study finds genetic aberrations linked to lung cancer; Could help in early diagnosis

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:5/3/2016)... , May 3, 2016  Neurotechnology, a ... the MegaMatcher Automated Biometric Identification System (ABIS) ... large-scale multi-biometric projects. MegaMatcher ABIS can process multiple ... using any combination of fingerprint, face or iris ... MegaMatcher SDK and MegaMatcher Accelerator , ...
    (Date:4/28/2016)... and BANGALORE, India , April ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... today announced a global partnership that will provide ... to use mobile banking and payment services.      ... a key innovation area for financial services, but it also ...
    (Date:4/28/2016)... , April 28, 2016 First quarter 2016: ... up 966% compared with the first quarter of 2015 ... SEK 589.1 M (loss: 18.8) and the operating margin was 40% ... 0.32) Cash flow from operations was SEK 249.9 M ... revenue guidance is unchanged, SEK 7,000-8,500 M. The operating ...
    Breaking Biology News(10 mins):
    (Date:5/4/2016)... ... May 05, 2016 , ... ... support the National Stroke Association during National Stroke Awareness Month in May. ... Twitter pages throughout the month. CereScan will donate $1 up to a ...
    (Date:5/4/2016)... ... 04, 2016 , ... Looking for a gift to give ... cooking experience. Offering everything from gourmet cooking classes to weekend culinary adventures, LaJollaCooks4u ... Guests that visit LaJollaCooks4u share an experience unlike any other. Each class takes ...
    (Date:5/4/2016)... ... 2016 , ... Proove Biosciences, Inc. , the commercial and research leader ... University . The partnership is designed to advance research in pain genetics in an ... pain. With the new agreement, researchers at Proove Biosciences are able to collaborate with ...
    (Date:5/4/2016)...  Bayer today announced that a Phase III ... (regorafenib) tablets for the treatment of patients with ... endpoint of a statistically significant improvement in overall ... and safety of regorafenib in patients with HCC ... The safety and tolerability were generally consistent with ...
    Breaking Biology Technology:
    Cached News: