HOME >> BIOLOGY >> NEWS
Could memory performance and spatial learning be genetically based?

12 swim trials were given per day over two consecutive days. Animals were placed into the maze at one of three randomized starting points and allowed to traverse the maze in search of the escape platform. On each trial, a maximum of 60 seconds of swim time was allowed. Between trials, a 35 second interval was imposed with the rat on the platform. At the end of the 24th trial, the platform was removed (probe trial) and the animal was allowed to search for one minute. The distance traveled in the target quadrant [T] and the three other quadrants adjacent-left [AL], adjacent-right [AR], and opposite[O] was expressed as a percentage of the total distance traveled.

  • In the visible platform version all visual cues were removed from the room, the platform was raised 2 cm above the surface of the water and two 15 cm high dark cylinders were attached to it. Twelve consecutive trials were then administered with a 35 second inter-trial interval, as above. The platform was moved in a random fashion between each trial.

    Genotyping (the "blueprint" or set of instructions for building and maintaining a live creature) was done with six chromosome X markers. Quantitative trait locus (QTL; the combined influences of numerous genes) analysis was performed using the cumulative distance traveled over the 24 trials as the index of acquisition performance (ACQTD). The percent of distance traveled on the probe trial was used as the index of spatial accuracy (SpA). Linkage map, marker regression and interval mapping analyses were done to generate a likelihood ratio statistic as a measure of the significance of a possible QTL. A backcross analytic design was used to perform both the permutation test as well as the QTL analysis. Genetic distances were calculated with a Kosambi mapping function, and critical significance values for interval mapping were determined by a permutation test.

    Two-Way Repeated Measures ANOVA, one-way ANOVA or t-tests (when indicated) w
    '"/>



    • Contact: Donna Krupa
    djkrupa1@aol.com
    703-527-7357
    American Physiological Society
    4-Feb-2004


    Page: 1 2 3

    Related biology news :

    1. Endometriosis: Could angiostatic therapy be the new treatment of the future?
    2. Could mice hold the secret to longer life?
    3. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
    4. Could a specific protein contribute to erectile dysfunction for the diabetic and obese?
    5. Could diabetes treatments fight cancer?
    6. Could rice be the source for a natural herbicide?
    7. Could hibernators hold the key to improving organ preservation?
    8. Could Bt transgenic crops have nutritionally favourable effects on insects?
    9. Could one less cookie a day help the fight against fat?
    10. Could an anti-marijuana compound hold the key to body weight and appetite control?
    11. Study finds genetic aberrations linked to lung cancer; Could help in early diagnosis

    Post Your Comments:
    (Date:5/22/2013)... a novel technique that can detect molecular variants in ... one of the most important, though time-consuming, processes in ... in Nature , post-doctoral researcher David Patterson, Professor ... the Center for Free-Electron Laser Science (CFEL) in Hamburg, ... fields to identify molecular variants apart, and to determine ...
    (Date:5/22/2013)... in cellular DNA can endanger the whole organism, as ... at Ludwig-Maximilians-Universitaet (LMU) in Munich now report how byproducts ... helix. , The DNA in our cells controls the ... bodies. The instructions for this are encoded in the ... the bases adenine (A), cytosine (C), guanine (G) and ...
    (Date:5/22/2013)... May 22, 2013. Plastic additives known as phthalates ... everywhere: They turn up in flooring, plastic cups, ... the Centers for Disease Control and Preventionthe bodies ... have come under increasing scrutiny. A growing collection ... can leech from packaging and mix with food) ...
    Breaking Biology News(10 mins):Detecting mirror molecules 2Detecting mirror molecules 3DNA damage: The dark side of respiration 2Study links chemicals widely found in plastics and processed food to elevated blood pressure in children and teens 2
    (Date:5/22/2013)... Chicago, IL (PRWEB) May 22, 2013 Alton ... thetelegraph.com dated May 15, 2013 said that their presence ... help other bed bug sufferers avoid such big spending, My ... bugs inexpensively. , It was said in the report ... an exterminator, MCP related. Apart from that, its employees also ...
    (Date:5/22/2013)... May 22, 2013  Moderna Therapeutics, the pioneering company ... to enable the in vivo production of ... will join Moderna in early July as ... is a proven leader in the design and implementation ... from discovery to translation, clinical operations and commercial preparedness. ...
    (Date:5/21/2013)... (PRWEB) May 21, 2013 Custom ... to reporting eLearning solution using Tin Can API ... dashboard tool. CLD is a leading developer of ... medical device companies worldwide. , Tin Can ... that helps learners and trainers more accurately measure ...
    (Date:5/21/2013)... May 21, 2013 The congress ... Transplant Association) is the biggest congress in ... Nearly 10,000 participants are in Istanbul ... research findings. New pioneering studies have been presented: ... PYROPHOSPHATE (SFP) ADMINISTERED VIA HEMODIALYSATE REDUCES ESA USE" ...
    Breaking Biology Technology:Bed Bugs Cost Alton Housing Authority $35,000; New Help, How to Kill Bed Bugs With Less Expense, Introduced by My Cleaning Products 2Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer 2Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer 3CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 2CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 3ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 2ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 3
    Cached News: