HOME >> BIOLOGY >> NEWS
Could mice hold the secret to longer life?

Scientists from the University of Aberdeen, the Aberdeen-based Rowett Research Institute and the Medical Research Council (MRC) in Cambridge have made a major breakthrough in understanding how metabolism affects lifespan.

In a seven-year study of mice they found that those with the highest metabolic rate lived the longest, raising the prospect that the effect could be mimicked in humans.

Scientists have long thought that a high metabolic rate was linked to a shortened life-span. The present discovery turns this century old belief on its head and changes dramatically our understanding of the regulation of life-span.

Metabolism is the means by which nutrients are broken down to smaller building blocks and chemical energy, which are used to make new body materials and to do work.

The researchers discovered that the most metabolically active 25% of the mice studied, far from having shorter life-spans, in fact lived 36% longer than the least active. If the same effects are mimicked in humans then the finding would imply that a higher metabolic rate could add an extra 27 years to the average human lifespan.

When the muscles of the most metabolically active mice were examined, they were found to contain factors that increased their metabolism by making it less efficient.

Although the scientists do not yet fully understand how these factors work, it is suspected that while the make the metabolism less efficient, on the positive side they reduce the generation of toxic by-products called "oxygen free radicals".


'"/>

Contact: Kate Stinchcombe
kate.stinchcombe@oxon.blackwellpublishing.com
Blackwell Publishing Ltd.
28-May-2004


Page: 1

Related biology news :

1. Endometriosis: Could angiostatic therapy be the new treatment of the future?
2. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
3. Could memory performance and spatial learning be genetically based?
4. Could a specific protein contribute to erectile dysfunction for the diabetic and obese?
5. Could diabetes treatments fight cancer?
6. Could rice be the source for a natural herbicide?
7. Could hibernators hold the key to improving organ preservation?
8. Could Bt transgenic crops have nutritionally favourable effects on insects?
9. Could one less cookie a day help the fight against fat?
10. Could an anti-marijuana compound hold the key to body weight and appetite control?
11. Study finds genetic aberrations linked to lung cancer; Could help in early diagnosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/12/2020)... ... 2020 , ... Mosio recently announced its newly updated text ... of all sizes. With a focus on tracking symptoms and monitoring outbreaks as ... Mosio helps public health departments automate communications and provide more personalized care and ...
(Date:8/3/2020)... ... 03, 2020 , ... Accumen Inc. is helping healthcare get ... Spectrum Solutions, to provide COVID-19 saliva testing kits nationally. , “Accumen has ... than 10 years. Early in the COVID-19 crisis, we identified supply chain gaps ...
(Date:7/18/2020)... (PRWEB) , ... July 16, 2020 , ... ... that demonstrates the effectiveness of the Invictus Medical Neoasis™ active noise control device ... The study reported that the Neoasis™ device attenuated the alarm sounds from patient ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... August 13, 2020 , ... Inc. magazine today ... most prestigious ranking of the nation’s fastest-growing private companies. The list represents a ... segment—its independent small businesses. Intuit, Zappos, Under Armour, Microsoft, Patagonia, and many other ...
(Date:8/3/2020)... ... August 03, 2020 , ... ERT, the ... CEO has been named one of the 100 most inspiring individuals in the ... honorees are selected based on how they have inspired their colleagues and affected ...
(Date:7/31/2020)... Mass. (PRWEB) , ... July 29, 2020 , ... ... wire that can combine up to three different materials for use with CRM, ... combine up to three materials to meet specific design requirements, performance, and cost ...
(Date:7/22/2020)... ... ... Join experts from Reed Tech , Gary Saner, Sr. Manager, Information Solutions Life ... webinar on Thursday, August 13, 2020 at 11am EDT (4pm BST/UK). , The ... medical devices, the NMPA has departments dealing with medical device registration (pre-market approvals) and ...
Breaking Biology Technology:
Cached News: