HOME >> BIOLOGY >> NEWS
Could mice hold the secret to longer life?

Scientists from the University of Aberdeen, the Aberdeen-based Rowett Research Institute and the Medical Research Council (MRC) in Cambridge have made a major breakthrough in understanding how metabolism affects lifespan.

In a seven-year study of mice they found that those with the highest metabolic rate lived the longest, raising the prospect that the effect could be mimicked in humans.

Scientists have long thought that a high metabolic rate was linked to a shortened life-span. The present discovery turns this century old belief on its head and changes dramatically our understanding of the regulation of life-span.

Metabolism is the means by which nutrients are broken down to smaller building blocks and chemical energy, which are used to make new body materials and to do work.

The researchers discovered that the most metabolically active 25% of the mice studied, far from having shorter life-spans, in fact lived 36% longer than the least active. If the same effects are mimicked in humans then the finding would imply that a higher metabolic rate could add an extra 27 years to the average human lifespan.

When the muscles of the most metabolically active mice were examined, they were found to contain factors that increased their metabolism by making it less efficient.

Although the scientists do not yet fully understand how these factors work, it is suspected that while the make the metabolism less efficient, on the positive side they reduce the generation of toxic by-products called "oxygen free radicals".


'"/>

Contact: Kate Stinchcombe
kate.stinchcombe@oxon.blackwellpublishing.com
Blackwell Publishing Ltd.
28-May-2004


Page: 1

Related biology news :

1. Endometriosis: Could angiostatic therapy be the new treatment of the future?
2. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
3. Could memory performance and spatial learning be genetically based?
4. Could a specific protein contribute to erectile dysfunction for the diabetic and obese?
5. Could diabetes treatments fight cancer?
6. Could rice be the source for a natural herbicide?
7. Could hibernators hold the key to improving organ preservation?
8. Could Bt transgenic crops have nutritionally favourable effects on insects?
9. Could one less cookie a day help the fight against fat?
10. Could an anti-marijuana compound hold the key to body weight and appetite control?
11. Study finds genetic aberrations linked to lung cancer; Could help in early diagnosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2020)... ... June 23, 2020 , ... ... services, today announced that the company has received ISO9001:2015 certification for the ... and research industries. The decision to pursue ISO9001 accreditation demonstrates Kemp’s commitment ...
(Date:6/19/2020)... ... , ... The director of stem cell biotechnology company Asymmetrex , Dr. ... pharmaceutical industries have easier access to stem cell counting, they will soon make it ... Independence Day weekend in the U.S., Asymmetrex is offering free tissue stem cell counting ...
(Date:6/11/2020)... ... 2020 , ... Superior Controls, Inc. , an E Technologies Company and ... life sciences industry, is pleased to announce the recent hiring of Ray Boudreau, who ... New Hampshire office. In his new role, Boudreau will use his extensive experience ...
Breaking Biology News(10 mins):
(Date:6/23/2020)... ... 2020 , ... Kerafast Inc. , developers of an ... availability of the Delta-G-VSV Pseudotyping System for coronavirus research applications. The system, developed ... viral entry and COVID-19 vaccine effectiveness at just biosafety level 2 (BSL-2) containment. ...
(Date:6/23/2020)... ... 2020 , ... Dracen Pharmaceuticals Inc., announced today that two ... the American Association for Cancer Research Virtual meeting. One poster describes the immuno-metabolism ... agent activity in KEAP1 mutant tumor models of NSCLC. , “As ...
(Date:6/11/2020)... ... , ... Greffex, a leading genetic engineering company, with the ... vectors, recently announced a key manufacturing agreement with FUJIFILM Diosynth Biotechnologies to produce ... successful gene therapy delivery vehicle (vector) with broad applications for delivering treatments including ...
(Date:6/11/2020)... ... June 09, 2020 , ... Reducing carbon emissions has ... From the Paris Agreement to stock market dips, ways to reduce CO2 is something ... to their portfolio. Most of the biofuels being produced today are created from recycled ...
Breaking Biology Technology:
Cached News: