HOME >> BIOLOGY >> NEWS
Counting the molecules that pull cells apart

"Cells obey the laws of physics and chemistry," begins a famous biology textbook, and one of the main goals of molecular biology is to link the properties of single molecules to the behavior of cells and the lives of organisms. So it is probably no surprise that an important new discovery about the physical forces that underlie cell division comes from a physics student-turned biologist, using math and a laser "scalpel" integrated into a microscope. The findings appear in the current issue of the journal Science.

Stephan Grill, Joe Howard, Erik Schffer, Ernst Stelzer and Tony Hyman - in a collaboration between the Max-Planck Institute of Molecular Cell Biology and Genetics in Dresden and EMBL in Heidelberg - have done something few scientists have managed: they have counted the number of proteins that help an egg cell divide. This initial division happens in a special way in the roundworm C. elegans, one of biology's most important model organisms.

"The fertilized egg splits into one large and one smaller cell," Grill says. "That difference in size is crucial to the development of the whole roundworm body. Normally people think of cells as dividing into two identical daughters; if they don't, there must be forces at work that create an imbalance. We wanted to map them."

As a PhD student at EMBL, working between the research groups of Tony Hyman and biophysicist/microscopist Ernst Stelzer, Grill pursued an intriguing lead. A cable-like network of proteins called microtubules tows freshly-copied DNA off to opposing sides of the cell. The identical sets of genetic material are then sealed off in their own cells. Normally the anchors that the tow-lines are attached to, called centrosomes, remain near the center of the cell. But in the roundworm egg, one centrosome wanders off towards the outer rim of the cell. Either it was being pulled there or pushed there, Grill reasoned, so he began zapping parts of the cell with a laser, trying to disrupt t
'"/>

Contact: Russ Hodge
info@embl.de
49-6221-387-252
European Molecular Biology Laboratory
24-Jul-2003


Page: 1 2 3

Related biology news :

1. Counting foxes before the last tally-ho
2. Counting the molecules that pull cells apart
3. Counting semi-viable bacteria in cheese
4. Counting salmon essential measure of recovery efforts
5. Counting the cost of genome projects
6. Counting elephants by monitoring sounds
7. Counting X Chromosomes To Determine Sex
8. Detecting Deer: New Method For Counting Population In Urban Areas
9. Tiny molecules have big potential as cancer drugs, Stanford researcher believes
10. Synthesized molecules studied as weapon to stop cell division in cancer cells
11. Scientists reinvent DNA as template to produce organic molecules

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/13/2018)... (PRWEB) , ... November 13, 2018 , ... ... Officer Jonathan Retano will be a featured presenter at the upcoming CBI Gross-to-Net ... host a hospitality suite on Friday, November 16, where conference attendees will have ...
(Date:11/13/2018)... (PRWEB) , ... November 12, ... ... Triangle Park-based management consulting firm specializing in the life sciences, healthcare, and ... lead for Cybersecurity and Compliance. Summerville will be responsible for overseeing CREO’s ...
(Date:11/13/2018)... ... , ... Kenall has enhanced the popular MedMaster MAEC Series LED luminaires with ... luminaires are equipped with symmetric ambient and asymmetric exam modes, and an IP65 rating ... be specified in pairs, the MAEC is 8” x 48” and has a delivered ...
Breaking Biology News(10 mins):
(Date:11/13/2018)... ... November 13, 2018 , ... ... Research Water Life Science® in Grants Pass, Oregon believes in the power of ... Aqua® Research Water Life Science® sponsors the Power of Water® on talk radio ...
(Date:11/9/2018)... JACKSONVILLE, Fla. (PRWEB) , ... November 08, 2018 ... ... companies in the United States, adopted a machine-learning powered approach to increasing recovery ... was centered around an Artificially Intelligent Collections (AIC) product developed by NLP Logix, ...
(Date:11/7/2018)... ... , ... Diversified Technologies, Inc. (DTI) has installed a PEF (Pulsed ... Technology and Innovation at ASU. Funded by a USDA NIFA SBIR, the purpose of ... and predator control applications. , Algae ponds get up to 50% consumed by predators ...
(Date:11/5/2018)... NASHVILLE, Tenn. (PRWEB) , ... November 05, 2018 ... ... Accredited radiology and telemedicine company backed by Siemens Healthineers and several healthcare VC ... blockchain based radiology solution and making a history by purchasing tokens and obtaining ...
Breaking Biology Technology:
Cached News: