HOME >> BIOLOGY >> NEWS
Cultured Neural Stem Cells Reduce Symptoms In Model Of Parkinsons Disease

For decades, researchers have imagined treating human diseases by replacing damaged cells with stem cells -- embryonic cells from which all other kinds of cells develop. While the potential benefits are enormous, such strategies have been limited by an uncertain supply of stem cells. Now, scientists have shown that neural stem cells can be multiplied and raised to maturity in the laboratory and that these cells can greatly reduce symptoms in an animal model of Parkinson's disease.

The study is the first to show that neural stem cells grown outside the body can form specific kinds of neurons -- in this case, dopamine-producing cells -- and that these neurons can survive and function normally when they are transplanted into the living brain. Dopamine is an important nerve signaling chemical, or neurotransmitter, and the loss of dopamine-producing cells in one region of the brain is responsible for the symptoms seen in Parkinson's disease. The new finding suggests that cells multiplied in culture may ultimately prove useful in treating Parkinson's and other nervous system diseases. It also provides new opportunities for studying how the brain develops that may greatly improve understanding of nervous system disorders, says Ronald McKay, Ph.D., of the National Institute of Neurological Disorders and Stroke (NINDS), senior author of the report which will appear in the August 1998 issue of Nature Neuroscience (1).

"Cells are the ultimate device for delivering substances to the brain, so this could become one of the most widely used therapies in medical research," says Dr. McKay.

Unlike the original cells of the embryo, which can form literally any kind of cell, neural stem cells are restricted to becoming nervous system cells. However, they still can develop into all the types of cells that make up the brain and spinal cord. The process in which cells that start out with unlimited potential fates develop into specific types
'"/>

Contact: Natalie Larsen
301/496-5751
NIH/National Institute of Neurological Disorders and Stroke
20-Jul-1998


Page: 1 2 3 4

Related biology news :

1. Cultured sea fans to be re-seeded in Florida keys national marine sanctuary
2. Neural stem cells take a step closer to the clinic
3. Neural biology explains ejaculation
4. Neural development in time and space
5. Neural signal that helps wire up brains movement circuit identified
6. Neural stem cells can develop into functional neurons
7. Neural stem cells move to damaged areas of brain after injury
8. Human Neural Stem Cells Advance Distant Prospect Of Reseeding Damaged Brain
9. Scientists Discover How Genes Work Together To Control Neural Development
10. Medicinal Leech May Offer Clues To Neural Regeneration
11. Cells may shoot messenger to halt protein production

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... 24, 2017 Research and Markets has announced ... Analysis & Trends - Industry Forecast to 2025" report to ... The ... a CAGR of around 15.1% over the next decade to reach ... analyzes the market estimates and forecasts for all the given segments ...
(Date:3/22/2017)... , March 21, 2017 ... Cloud used by retailers such as 1-800-Flowers and ... platform — Product Recommendations and Replenishment. Using Optimove,s machine ... more personalized product and replenishment recommendations to their ... also on predictions of customer intent drawn from ...
(Date:3/16/2017)... - Against identity fraud with DERMALOG solutions "Made in Germany "  ... ... multi-biometric solutions provide a crucial contribution against identity fraud. (PRNewsFoto/Dermalog Identification Systems) ... Used combined in one project, multi-biometric solutions provide a crucial contribution against identity ... ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... ... April 27, 2017 , ... ... today announced their digital pathology technology has the potential to eliminate subjectivity in ... centers in The Netherlands as part of the 2017 ISBI CAMELYON Digital ...
(Date:4/27/2017)... ... April 27, 2017 , ... During the course of ... testing for 1,25-Dihydroxyvitamin D can enhance clinical practice. Participants will learn the medical ... D. , Dr. Gregory Plotnikoff, senior consultant with Minnesota Personalized Medicine, will be ...
(Date:4/27/2017)... (PRWEB) , ... April 27, 2017 , ... ... the 2017 Borlaug CAST Communication Award goes to Jayson Lusk, a consummate communicator ... forms of media to advocate for science, as he explains how innovation and ...
(Date:4/26/2017)... ... 26, 2017 , ... WonderWorks, Myrtle Beach’s science focused amusement ... of deep space exploration and inspire space enthusiasts. The exhibit features interactive exhibits ... guest appearance by former Shuttle Astronaut Don Thomas. , The intergalactic weekend kicks ...
Breaking Biology Technology:
Cached News: