HOME >> BIOLOGY >> NEWS
Cultured Neural Stem Cells Reduce Symptoms In Model Of Parkinsons Disease

For decades, researchers have imagined treating human diseases by replacing damaged cells with stem cells -- embryonic cells from which all other kinds of cells develop. While the potential benefits are enormous, such strategies have been limited by an uncertain supply of stem cells. Now, scientists have shown that neural stem cells can be multiplied and raised to maturity in the laboratory and that these cells can greatly reduce symptoms in an animal model of Parkinson's disease.

The study is the first to show that neural stem cells grown outside the body can form specific kinds of neurons -- in this case, dopamine-producing cells -- and that these neurons can survive and function normally when they are transplanted into the living brain. Dopamine is an important nerve signaling chemical, or neurotransmitter, and the loss of dopamine-producing cells in one region of the brain is responsible for the symptoms seen in Parkinson's disease. The new finding suggests that cells multiplied in culture may ultimately prove useful in treating Parkinson's and other nervous system diseases. It also provides new opportunities for studying how the brain develops that may greatly improve understanding of nervous system disorders, says Ronald McKay, Ph.D., of the National Institute of Neurological Disorders and Stroke (NINDS), senior author of the report which will appear in the August 1998 issue of Nature Neuroscience (1).

"Cells are the ultimate device for delivering substances to the brain, so this could become one of the most widely used therapies in medical research," says Dr. McKay.

Unlike the original cells of the embryo, which can form literally any kind of cell, neural stem cells are restricted to becoming nervous system cells. However, they still can develop into all the types of cells that make up the brain and spinal cord. The process in which cells that start out with unlimited potential fates develop into specific types
'"/>

Contact: Natalie Larsen
301/496-5751
NIH/National Institute of Neurological Disorders and Stroke
20-Jul-1998


Page: 1 2 3 4

Related biology news :

1. Cultured sea fans to be re-seeded in Florida keys national marine sanctuary
2. Neural stem cells take a step closer to the clinic
3. Neural biology explains ejaculation
4. Neural development in time and space
5. Neural signal that helps wire up brains movement circuit identified
6. Neural stem cells can develop into functional neurons
7. Neural stem cells move to damaged areas of brain after injury
8. Human Neural Stem Cells Advance Distant Prospect Of Reseeding Damaged Brain
9. Scientists Discover How Genes Work Together To Control Neural Development
10. Medicinal Leech May Offer Clues To Neural Regeneration
11. Cells may shoot messenger to halt protein production

Post Your Comments:
(Date:4/15/2014)... are many viral diseases in the world for which ... fever, which is spread by mosquitoes in the tropics, ... more familiar in Finland and is easily spread by ... children and the elderly. , Researchers at Aalto University ... in preliminary tests to prevent the spread of one ...
(Date:4/15/2014)... parasites of cuttlefish, squid and octopus has uncovered ... shown how they may help in investigating populations ... has described 10 new parasite species− dicyemid mesozoans ... (cuttlefish, squid and octopus). They are the ... Australian waters. , "Although dicyemid parasites have ...
(Date:4/15/2014)... 15, 2014) New research published in the ... American College of Nutrition shows whey protein, either ... part of a weight-loss or weight-maintenance diet, may provide ... , The meta-analysis included 14 randomized controlled trials with ... those weight loss studies that used whey protein to ...
Breaking Biology News(10 mins):Nanocrystalline cellulose modified into an efficient viral inhibitor 2Bizarre parasite may provide cuttlefish clues 2New meta-analysis builds on the power of whey protein for improved body composition 2New meta-analysis builds on the power of whey protein for improved body composition 3
(Date:1/15/2014)... January 15, 2014 This webinar ... on nonclinical and clinical safety assessment in biosimilars. ... guide a path for biosimilar drug development, however ... of biosimilarity with regards to quality, safety and ... of biosimilar drug development and registration, development strategies ...
(Date:1/15/2014)... NC (PRWEB) January 15, 2014 ... an enhancement to its Online Web Portal for Life ... now have the ability to specify the subject matter ... nearly 50 life science sub-domains. This will help reduce ... and scientific fields, and decrease the likelihood of error. ...
(Date:1/14/2014)... Doylestown, PA (PRWEB) January 14, 2014 ... – 11 p.m. , Location: Warrington Country Club, 1360 ... Hepatitis B Foundation, the only national nonprofit organization solely ... improving the quality of life for those affected worldwide, ... 11 at Warrington Country Club in Warrington, Pa. ...
(Date:1/14/2014)... York, NY (PRWEB) January 14, 2014 ... initiated coverage of Alliqua, Inc. (OTCQB: ALQA). Alliqua ... and marketing proprietary products to serve the wound ... , In late 2012, Alliqua was restructured ... launched the company’s new strategy to become a ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
Cached News: