HOME >> BIOLOGY >> NEWS
Cultured Neural Stem Cells Reduce Symptoms In Model Of Parkinsons Disease

For decades, researchers have imagined treating human diseases by replacing damaged cells with stem cells -- embryonic cells from which all other kinds of cells develop. While the potential benefits are enormous, such strategies have been limited by an uncertain supply of stem cells. Now, scientists have shown that neural stem cells can be multiplied and raised to maturity in the laboratory and that these cells can greatly reduce symptoms in an animal model of Parkinson's disease.

The study is the first to show that neural stem cells grown outside the body can form specific kinds of neurons -- in this case, dopamine-producing cells -- and that these neurons can survive and function normally when they are transplanted into the living brain. Dopamine is an important nerve signaling chemical, or neurotransmitter, and the loss of dopamine-producing cells in one region of the brain is responsible for the symptoms seen in Parkinson's disease. The new finding suggests that cells multiplied in culture may ultimately prove useful in treating Parkinson's and other nervous system diseases. It also provides new opportunities for studying how the brain develops that may greatly improve understanding of nervous system disorders, says Ronald McKay, Ph.D., of the National Institute of Neurological Disorders and Stroke (NINDS), senior author of the report which will appear in the August 1998 issue of Nature Neuroscience (1).

"Cells are the ultimate device for delivering substances to the brain, so this could become one of the most widely used therapies in medical research," says Dr. McKay.

Unlike the original cells of the embryo, which can form literally any kind of cell, neural stem cells are restricted to becoming nervous system cells. However, they still can develop into all the types of cells that make up the brain and spinal cord. The process in which cells that start out with unlimited potential fates develop into specific types
'"/>

Contact: Natalie Larsen
301/496-5751
NIH/National Institute of Neurological Disorders and Stroke
20-Jul-1998


Page: 1 2 3 4

Related biology news :

1. Cultured sea fans to be re-seeded in Florida keys national marine sanctuary
2. Neural stem cells take a step closer to the clinic
3. Neural biology explains ejaculation
4. Neural development in time and space
5. Neural signal that helps wire up brains movement circuit identified
6. Neural stem cells can develop into functional neurons
7. Neural stem cells move to damaged areas of brain after injury
8. Human Neural Stem Cells Advance Distant Prospect Of Reseeding Damaged Brain
9. Scientists Discover How Genes Work Together To Control Neural Development
10. Medicinal Leech May Offer Clues To Neural Regeneration
11. Cells may shoot messenger to halt protein production

Post Your Comments:
(Date:7/27/2015)... July 27, 2015  Synaptics Inc. (NASDAQ: ... solutions, today announced that Huawei has selected the ... for its stylish smartwatch. Huawei chose the state-of-the-art ... low power and highly responsive human interface qualities ... designers also required a classic round watch face ...
(Date:7/27/2015)... , July 27, 2015   Zynx Health ... experience-based clinical improvement solutions, today announced that its ... now available on Android smartphones and tablets. With ... post-care organizations can use ZynxCarebook to securely exchange ... condition, streamline care transitions to other care settings, ...
(Date:7/23/2015)... Inc. (NASDAQ: AWRE ), a leading supplier of biometrics ... quarter ended June 30, 2015.  Revenue for ... of 33% compared to $6.8 million in the same quarter ... was $0.3 million, or $0.01 per diluted share, which compared ... same period a year ago.  Lower revenue ...
Breaking Biology News(10 mins):Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6
(Date:7/28/2015)... A n ew UK ... and commercialising innovative medicines to transform patient quality of life ... management team; blue chip investor ... Group Ltd ("Mereo"), a recently-formed speciality biopharmaceutical company, announces that ... from blue chip institutional investors and simultaneously acquired a portfolio ...
(Date:7/28/2015)... ... July 29, 2015 , ... Strong Animals™ announced today that research ... operation and presented at the ADSA-ASAS Joint Annual Meeting held July 12-16 in Orlando, ... cows and increased milk fat content. Also, feed containing Stay Strong™ for Dairy Cows ...
(Date:7/28/2015)... ... July 29, 2015 , ... The new Xsample 530 sample changer for vials ... wide range of liquid viscosities – from less than 12,000 mPas (internal air) up to ... , What immediately catches the eye about Xsample 530 is its removable magazine, which ...
(Date:7/28/2015)... 28, 2015  PDL BioPharma, Inc. (PDL, or the ... Company will release its second quarter 2015 financial results ... August 5, 2015, after market close. PDL,s management will ... 4:30 p.m. Eastern Time to discuss the financial results. ... available via the webcast link on the PDL website. ...
Breaking Biology Technology:Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 2Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 3Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 4Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 5Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 6Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 7Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 8Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 9Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 10Mereo BioPharma Announces Formal Launch of Company; Raises $119m (c.£76.5m) and Acquires Innovative Mid-Stage Clinical Product Portfolio From Leading Pharmaceutical Company 11Strong Animals™ Announces South Dakota State University Research Demonstrates Stay Strong™ for Dairy Cows Improves Performance and Feed Stability 2New Moves in Automatic Sample Handling: Introducing Xsample 530 2PDL BioPharma to Announce Second Quarter 2015 Financial Results on August 5, 2015 2
Cached News: