Current HIV treatment guidelines may result in more men than women being eligible for treatment

July 7, 2000 -- Helping to clarify a long-standing issue, a study by researchers at Johns Hopkins shows that women carry lower levels of HIV in their blood than men, especially during early phases of the infection, but have the same risk as men of developing AIDS. One consequence of the findings: viral load thresholds used by doctors to begin anti-retroviral drug therapy could result in more men getting offered treatment than women, particularly early in the course of infection.

"You would assume that if women start out with a lower viral load than men, they would have a lower risk of progressing to AIDS, but they have the same risk," says Timothy Sterling, M.D., an assistant professor of infectious diseases at the Johns Hopkins Medical Institutions. Sterling presents the research on July 11 at the 13th International AIDS Conference in Durban, South Africa.

Currently, doctors generally offer anti-retroviral treatment to patients when tests indicate greater than 20,000 copies of HIV per milliliter of blood. The Hopkins team found that while both men and women had the same risk of developing AIDS, women had lower viral loads than men during the first few years of becoming HIV positive. While men who progressed to AIDS had average viral loads of roughly 78,000 copies per ml in the first year, women who progressed to AIDS only had 17,000 copies per ml. Women continued to have lower HIV levels than men in subsequent years, but by the fourth year, the differences tended to dissipate.

Over the past several years, various studies have yielded conflicting results as to whether viral loads differ between HIV-positive men and women. Using data from the AIDS Linked to Intravenous Experience (ALIVE) study of 3,380 intravenous drug users, Sterling and his colleagues studied individuals who had contracted HIV within 12 months of a previous visit and before December 1 of 1997. Out of the total ALIVE group, 202 qualified for their study

Contact: Kate O'Rourke
Johns Hopkins Medical Institutions

Page: 1 2

Related biology news :

1. Current smoke alarms pass life-saving tests
2. Current growing nursing shortage to be studied at 160 US acute care hospitals
3. New Findings On Primitive Shark Contradicts Current View Of Jaw Evolution
4. Comprehensive Nutritional Status In Patients With Long-Standing Crohn Disease Currently In Remission
5. New Tuberculosis Vaccine Candidate Developed: Improved Delivery Of Antigens By Current Vaccine BCG (Bacille Calmette-Gurin)
6. Leader in cancer treatment and prevention research honored
7. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
8. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
9. New treatment for fibromyalgia
10. The impact of genetic variations on the treatment of early rheumatoid arthritis
11. OneWorld Health compiles comprehensive state of infectious diarrhea treatments, potential solutions

Post Your Comments:

(Date:4/5/2017)... 5, 2017 Today HYPR Corp. , ... server component of the HYPR platform is officially ... end-to-end security architecture that empowers biometric authentication across Fortune ... already secured over 15 million users across the financial ... connected home product suites and physical access represent a ...
(Date:3/30/2017)... 2017  On April 6-7, 2017, Sequencing.com will host ... hackathon at Microsoft,s headquarters in Redmond, ... on developing health and wellness apps that provide a ... Genome is the first hackathon for personal genomics ... companies in the genomics, tech and health industries are ...
(Date:3/28/2017)... , March 28, 2017 ... Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video ... and Region - Global Forecast to 2022", published by ... in 2016 and is projected to reach USD 75.64 ... 2017 and 2022. The base year considered for the ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... of a complex biological network, a depiction of a system of linkages and ... Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute (WPI) ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... partners with the pharmaceutical and biotechnology industries to improve patient outcomes and quality ... Several trends in analytical testing are being attributed to new regulatory requirements for ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ComplianceOnline’s Medical ... place on 7th and 8th June 2018 in San Francisco, CA. The Summit brings ... well as several distinguished CEOs, board directors and government officials from around the world ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new ... rates in frozen and fresh in vitro fertilization (IVF) transfer cycles. ... to IVF success. , After comparing the results from the fresh and frozen ...
Breaking Biology Technology:
Cached News: