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Cyclacel's biomarker technology shows that CYC202 induces cancer cells to commit suicide

assess the effects of the drug on patients receiving CYC202 in combination with chemotherapy."

"The results presented at AACR confirm Cyclacel's technological leadership in the emerging field of biomarkers," said Spiro Rombotis, CEO. "This is a strategic technology facilitating more efficient investments in drug development programmes. Biomarkers help determine clinical go/no go decisions very early in clinical development and are also proving invaluable in demonstrating early proof of concept in humans. We believe that biomarkers will be a source of competitive advantage in pivotal trials and market positioning by helping identify responder patients based on their genetic profile. We are excited about the work of our talented Biomarker Team and our goal of converting our understanding of biological pathways into patient treatment guidelines. We expect to use our Biomarker technology in additional drug programmes as they progress into clinical trials."


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Contact: Robert Gottlieb
robert.gottlieb@fkhealth.com
617-577-8110
Feinstein Kean Healthcare
14-Jul-2003


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