HOME >> BIOLOGY >> NEWS
DNA deletion offers new evidence of mammals' origins

Cincinnati - What's missing might turn out to be as important as what's actually there in uncovering the roots of the mammalian tree of life.

A team of biologists led by Mark Springer at the University of California, Riverside and including Ronald DeBry of the University of Cincinnati report in the Feb. 1 issue of Nature that an intensive analysis of DNA sequences provides strong support for a grouping Springer dubs "Afrotheria." The group includes a variety of placental mammals from elephants to elephant shrews. And add in aardvarks, manatees, and hyraxes to boot.

"One of the problems with mammal phylogenies is there hasn't been a lot known," explained DeBry. "We were searching for the basic outline of the tree of life."

Traditional phylogenies, or evolutionary trees, were based on fossil evidence and physical similarities. To complicate things further, there was a huge explosion of mammalian groups right after dinosaurs went extinct.

"Finding the base of the tree has been difficult," said DeBry. "There are lots and lots of questions."

Over the last 10 years, DNA studies have confirmed some patterns proposed by those studying fossil evidence and physical similarities. Other DNA studies turned up new and unexpected relationships. The picture quickly got muddier and muddier.

"What we needed was a BIG data set," said DeBry. "Our data set has six different genes and 8600 base pairs." Two of the genes are found in mitochondrial DNA. The other four are found in the chromosomes of the nucleus, including BRCA-1, commonly known as the breast cancer gene.

Springer, DeBry and the other co-authors report that a specific deletion of nine base pairs in BRCA-1 is shared by 12 groups of placental mammals. These are the groups Springer puts together in "Afrotheria."

In addition, the exhaustive comparison helps to answer a more recent question: How closely are rabbits and guinea pigs related to rodents? The results in Nature indicate
'"/>

Contact: Chris Curran
chris.curran@uc.edu
513-556-1806
University of Cincinnati
31-Jan-2001


Page: 1 2

Related biology news :

1. Rare childhood bone disorder linked to gene deletion in two Navajo patients
2. Watching clonal deletion in action
3. Lake research offers clues to managing crayfish invasions
4. Comparing primate genomes offers insight into human evolution
5. Study of proteins offers insights into organization of biological networks
6. Susceptibility of mice to mousepox offers promise of smallpox protection
7. Botulinum toxin structure offers clues for vaccines/treatments
8. Discovery offers clues to origin of life
9. Guiding gas exploration: U-M research offers inexpensive tool
10. New approach offers potential drug-discovery shortcut
11. American Society of Plant Biologists offers developing nations free access to science journals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2016)... facilitates superior patient care by providing unparalleled technology to leaders of the medical imaging ... product recently added to the range of products distributed by Ampronix. Photo ... ... ... News ...
(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com ... just published the overview results from the Q1 wave ... the recent wave was consumers, receptivity to a program ... data with a health insurance company. "We ... to share," says Michael LaColla , CEO of ...
(Date:4/28/2016)... , April 28, 2016 Infosys ... (NYSE: INFY ), and Samsung SDS, a global ... that will provide end customers with a more secure, fast ...      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) , ... but it also plays a fundamental part in enabling and ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... 24, 2016  Regular discussions on a range of subjects ... the two entities said Poloz. Speaking at a ... , he pointed to the country,s inflation target, which ... "In certain areas ... have common economic goals, why not sit down and address ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... release of its second eBook, ā€œClinical Trials Patient Recruitment and Retention Tips.ā€ Partnering ... retention in this eBook by providing practical tips, tools, and strategies for clinical ...
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
(Date:6/23/2016)... NEW YORK , June, 23, 2016  The ... students to envision new ways to harness living systems ... of Modern Art (MoMA) in New York ... more than 130 participating students, showcased projects at MoMA,s ... included Paola Antonelli , MoMA,s senior curator of ...
Breaking Biology Technology:
Cached News: