HOME >> BIOLOGY >> NEWS
DNA deletion offers new evidence of mammals' origins

Cincinnati - What's missing might turn out to be as important as what's actually there in uncovering the roots of the mammalian tree of life.

A team of biologists led by Mark Springer at the University of California, Riverside and including Ronald DeBry of the University of Cincinnati report in the Feb. 1 issue of Nature that an intensive analysis of DNA sequences provides strong support for a grouping Springer dubs "Afrotheria." The group includes a variety of placental mammals from elephants to elephant shrews. And add in aardvarks, manatees, and hyraxes to boot.

"One of the problems with mammal phylogenies is there hasn't been a lot known," explained DeBry. "We were searching for the basic outline of the tree of life."

Traditional phylogenies, or evolutionary trees, were based on fossil evidence and physical similarities. To complicate things further, there was a huge explosion of mammalian groups right after dinosaurs went extinct.

"Finding the base of the tree has been difficult," said DeBry. "There are lots and lots of questions."

Over the last 10 years, DNA studies have confirmed some patterns proposed by those studying fossil evidence and physical similarities. Other DNA studies turned up new and unexpected relationships. The picture quickly got muddier and muddier.

"What we needed was a BIG data set," said DeBry. "Our data set has six different genes and 8600 base pairs." Two of the genes are found in mitochondrial DNA. The other four are found in the chromosomes of the nucleus, including BRCA-1, commonly known as the breast cancer gene.

Springer, DeBry and the other co-authors report that a specific deletion of nine base pairs in BRCA-1 is shared by 12 groups of placental mammals. These are the groups Springer puts together in "Afrotheria."

In addition, the exhaustive comparison helps to answer a more recent question: How closely are rabbits and guinea pigs related to rodents? The results in Nature indicate
'"/>

Contact: Chris Curran
chris.curran@uc.edu
513-556-1806
University of Cincinnati
31-Jan-2001


Page: 1 2

Related biology news :

1. Rare childhood bone disorder linked to gene deletion in two Navajo patients
2. Watching clonal deletion in action
3. Lake research offers clues to managing crayfish invasions
4. Comparing primate genomes offers insight into human evolution
5. Study of proteins offers insights into organization of biological networks
6. Susceptibility of mice to mousepox offers promise of smallpox protection
7. Botulinum toxin structure offers clues for vaccines/treatments
8. Discovery offers clues to origin of life
9. Guiding gas exploration: U-M research offers inexpensive tool
10. New approach offers potential drug-discovery shortcut
11. American Society of Plant Biologists offers developing nations free access to science journals

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: DNA deletion offers new evidence mammals origins

(Date:7/30/2015)... 30, 2015 Cellecta, Inc., a U.S.-based ... analysis and biomarker discovery, announced the release of ... targeting all human protein coding genes. CRISPR technology ... a gene,s function. Cellecta,s new Human Whole Genome ... tool so that researchers can investigate in a ...
(Date:7/23/2015)... (NASDAQ: AWRE ), a leading supplier of biometrics software ... ended June 30, 2015.  Revenue for the ... 33% compared to $6.8 million in the same quarter last ... $0.3 million, or $0.01 per diluted share, which compared to ... period a year ago.  Lower revenue and ...
(Date:7/21/2015)... , July 21, 2015  NXT-ID, Inc. ... a biometric authentication company focused on the growing ... smart wallet, announces that it has filed provisional ... and Method. This invention highlights ... only authorizes an account, but also the user ...
Breaking Biology News(10 mins):CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 2NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 4
(Date:7/30/2015)... ... July 31, 2015 , ... Ralco is honored to announce that ... County Fair to be held August 5-9 in Marshall. The Ralco Enrichment Center is ... from and how agriculture impacts their daily lives. This unique exhibit also features a ...
(Date:7/30/2015)... ... ... The 2015 Market Research Report on the Global Propanol Industry is ... with a focus on the Chinese situation. Major companies included in the propanol market ... Royal Dutch Shell, LG Chem and Zhejiang Xinhua Chemical. , The report provides a ...
(Date:7/30/2015)...   Senomyx , Inc. (NASDAQ: SNMX ), ... discover, develop, and commercialize novel flavor ingredients for the ... results for the second quarter 2015. ... on track to achieve our commercial and financial goals," ... the Company. "Since our last quarterly earnings report, our ...
(Date:7/30/2015)... WARRINGTON, Pa. , July 30, 2015 /PRNewswire/ ... announced that it has received the second $1.0M ... Business Innovation Research (SBIR) grant valued at up ... the company,s aerosolized KL4 surfactant as a potential ... lung injury.  Discovery Labs was awarded an initial ...
Breaking Biology Technology:Ralco Announces Primary Sponsorship of Ralco Enrichment Center at Lyon County Fair 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 4SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 5SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 6SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 7SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 8SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 9Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 2Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 3
Cached News: