HOME >> BIOLOGY >> NEWS
DNA deletion offers new evidence of mammals' origins

Cincinnati - What's missing might turn out to be as important as what's actually there in uncovering the roots of the mammalian tree of life.

A team of biologists led by Mark Springer at the University of California, Riverside and including Ronald DeBry of the University of Cincinnati report in the Feb. 1 issue of Nature that an intensive analysis of DNA sequences provides strong support for a grouping Springer dubs "Afrotheria." The group includes a variety of placental mammals from elephants to elephant shrews. And add in aardvarks, manatees, and hyraxes to boot.

"One of the problems with mammal phylogenies is there hasn't been a lot known," explained DeBry. "We were searching for the basic outline of the tree of life."

Traditional phylogenies, or evolutionary trees, were based on fossil evidence and physical similarities. To complicate things further, there was a huge explosion of mammalian groups right after dinosaurs went extinct.

"Finding the base of the tree has been difficult," said DeBry. "There are lots and lots of questions."

Over the last 10 years, DNA studies have confirmed some patterns proposed by those studying fossil evidence and physical similarities. Other DNA studies turned up new and unexpected relationships. The picture quickly got muddier and muddier.

"What we needed was a BIG data set," said DeBry. "Our data set has six different genes and 8600 base pairs." Two of the genes are found in mitochondrial DNA. The other four are found in the chromosomes of the nucleus, including BRCA-1, commonly known as the breast cancer gene.

Springer, DeBry and the other co-authors report that a specific deletion of nine base pairs in BRCA-1 is shared by 12 groups of placental mammals. These are the groups Springer puts together in "Afrotheria."

In addition, the exhaustive comparison helps to answer a more recent question: How closely are rabbits and guinea pigs related to rodents? The results in Nature indicate
'"/>

Contact: Chris Curran
chris.curran@uc.edu
513-556-1806
University of Cincinnati
31-Jan-2001


Page: 1 2

Related biology news :

1. Rare childhood bone disorder linked to gene deletion in two Navajo patients
2. Watching clonal deletion in action
3. Lake research offers clues to managing crayfish invasions
4. Comparing primate genomes offers insight into human evolution
5. Study of proteins offers insights into organization of biological networks
6. Susceptibility of mice to mousepox offers promise of smallpox protection
7. Botulinum toxin structure offers clues for vaccines/treatments
8. Discovery offers clues to origin of life
9. Guiding gas exploration: U-M research offers inexpensive tool
10. New approach offers potential drug-discovery shortcut
11. American Society of Plant Biologists offers developing nations free access to science journals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... , April 24, 2017 Janice ... partner with  Identity Strategy Partners, LLP (IdSP) , ... or without President Trump,s March 6, 2017 ... Entry , refugee vetting can be instilled with greater ... (Right now, all refugee applications are suspended by ...
(Date:4/13/2017)... 2017 According to a new market research report ... Identity Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region ... expected to grow from USD 14.30 Billion in 2017 to USD 31.75 ... ... MarketsandMarkets Logo ...
(Date:4/6/2017)... 6, 2017 Forecasts by Product ... Readers, by End-Use (Transportation & Logistics, Government & Public ... & Fossil Generation Facility, Nuclear Power), Industrial, Retail, Business ... Are you looking for a definitive report on ... ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... San Diego, CA (PRWEB) , ... ... ... BioInformatics (https://www.onramp.bio/ ) has launched Rosalind™, the first-ever genomics analysis platform ... eliminating all bioinformatics complexity. Named in honor of pioneering researcher Rosalind Franklin, ...
(Date:10/11/2017)... ... October 11, 2017 , ... The ... context, enabling overexpression experiments and avoiding the use of exogenous expression plasmids. The ... transformative for performing systematic gain-of-function studies. , This complement to loss-of-function studies, ...
(Date:10/11/2017)... ... October 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its ... 2018 in San Francisco, CA. The Summit brings together current and former FDA office ... directors and government officials from around the world to address key issues in device ...
(Date:10/11/2017)... BioMarketing, a leading provider of patient support solutions, has announced ... network, which will launch this week. The VMS CNEs will ... to enhance the patient care experience by delivering peer-to-peer education ... professionals to help women who have been diagnosed and are ... ...
Breaking Biology Technology:
Cached News: