HOME >> BIOLOGY >> NEWS
DNA registry to study links among genetics, environment, disease

CHAPEL HILL -- Scientists at the University of North Carolina at Chapel Hill and the National Institute of Environmental Health Sciences (NIEHS) are developing a voluntary DNA registry to study the link among environmental exposures, genetic susceptibility and human disease.

Eventually to include 20,000 patients at various UNC medical facilities, the Environmental Polymorphism Registry will be unlike the many anonymous DNA repositories that have developed since the advent and recent completion of the human genome initiatives - in that patient identifiers will be maintained in coded form.

This innovation will allow scientists to contact registry participants at a later date for their permission to obtain additional information, to invite their participation in additional studies and to offer them the option to drop out of the registry. Currently, no similar resources are available to the National Institutes of Health or to researchers at UNC.

"This is a pioneering initiative," said Dr. Paul B. Watkins, professor of medicine and director of the university's Caviness General Clinical Research Center. "Clearly, this is the next step that's needed to increase our understanding of how genes interact with the environment, including the body's response to medicines."

The registry was initiated by Dr. Perry Blackshear, NIEHS director of clinical research, and Dr. Patricia Chulada, health science administrator at the institute in Research Triangle Park. Also collaborating with Watkins at UNC is Susan Pusek, General Clinical Research Center director of training and career development.

Data from follow-up studies will help scientists identify groups of individuals with genetic polymorphisms, or variants, in "environmentally sensitive" genes and possibly to correlate these genetic variants with clinical histories and current health status.

These genes control how the human body interacts with substances from the environment, encoding pro
'"/>

Contact: Leslie Lang
llang@med.unc.edu
919-843-9687
University of North Carolina School of Medicine
8-Jan-2004


Page: 1 2

Related biology news :

1. NIEHS and UNC to collaborate on registry of 20,000 subjects
2. ART laws put patients at risk and should be changed, warns head of Germanys IVF registry
3. UNC, other physicians setting up national registry
4. Israeli fertility experts call for international chromosome registry
5. K-State veterinarians lab site for DNA registry
6. Student science contest participation influences study, career choices, alumni say
7. New study shows hope for treating inhalant abuse
8. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
9. Cigarette smoke causes breaks in DNA and defects to a cells chromosomes, Pitt study finds
10. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
11. Phase II trials of second-generation antisense cancer drug planned following successful early study

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/30/2017)... Today, American Trucking Associations announced Seeing ... and eye tracking software, became the newest member ... "Artificial intelligence and advanced sensing algorithms ... driver,s attentiveness levels while on the road.  Drivers ... fatigue and prevent potential accidents, which could lead ...
(Date:5/16/2017)... 2017  Veratad Technologies, LLC ( www.veratad.com ), an ... identity verification solutions, announced today they will participate as ... 15 thru May 17, 2017, in Washington ... Center. Identity impacts the lives of ... quickly evolving digital world, defining identity is critical to ...
(Date:4/19/2017)... York , April 19, 2017 ... as its vendor landscape is marked by the presence ... market is however held by five major players - ... Together these companies accounted for nearly 61% of the ... the leading companies in the global military biometrics market ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... They ... a complex biological network, a depiction of a system of linkages and connections ... Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute (WPI) and ...
(Date:10/12/2017)... ... 2017 , ... BioMedGPS announces expanded coverage of SmartTRAK Business ... US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats and Sealants module ... and biologic sealants used in surgical applications. BioMedGPS estimates the market will grow ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... its endogenous context, enabling overexpression experiments and avoiding the use of exogenous expression ... guides is transformative for performing systematic gain-of-function studies. , This complement to ...
(Date:10/11/2017)... BioMarketing, a leading provider of patient support solutions, has announced ... network, which will launch this week. The VMS CNEs will ... to enhance the patient care experience by delivering peer-to-peer education ... professionals to help women who have been diagnosed and are ... ...
Breaking Biology Technology:
Cached News: