HOME >> BIOLOGY >> NEWS
DNA registry to study links among genetics, environment, disease

CHAPEL HILL -- Scientists at the University of North Carolina at Chapel Hill and the National Institute of Environmental Health Sciences (NIEHS) are developing a voluntary DNA registry to study the link among environmental exposures, genetic susceptibility and human disease.

Eventually to include 20,000 patients at various UNC medical facilities, the Environmental Polymorphism Registry will be unlike the many anonymous DNA repositories that have developed since the advent and recent completion of the human genome initiatives - in that patient identifiers will be maintained in coded form.

This innovation will allow scientists to contact registry participants at a later date for their permission to obtain additional information, to invite their participation in additional studies and to offer them the option to drop out of the registry. Currently, no similar resources are available to the National Institutes of Health or to researchers at UNC.

"This is a pioneering initiative," said Dr. Paul B. Watkins, professor of medicine and director of the university's Caviness General Clinical Research Center. "Clearly, this is the next step that's needed to increase our understanding of how genes interact with the environment, including the body's response to medicines."

The registry was initiated by Dr. Perry Blackshear, NIEHS director of clinical research, and Dr. Patricia Chulada, health science administrator at the institute in Research Triangle Park. Also collaborating with Watkins at UNC is Susan Pusek, General Clinical Research Center director of training and career development.

Data from follow-up studies will help scientists identify groups of individuals with genetic polymorphisms, or variants, in "environmentally sensitive" genes and possibly to correlate these genetic variants with clinical histories and current health status.

These genes control how the human body interacts with substances from the environment, encoding pro
'"/>

Contact: Leslie Lang
llang@med.unc.edu
919-843-9687
University of North Carolina School of Medicine
8-Jan-2004


Page: 1 2

Related biology news :

1. NIEHS and UNC to collaborate on registry of 20,000 subjects
2. ART laws put patients at risk and should be changed, warns head of Germanys IVF registry
3. UNC, other physicians setting up national registry
4. Israeli fertility experts call for international chromosome registry
5. K-State veterinarians lab site for DNA registry
6. Student science contest participation influences study, career choices, alumni say
7. New study shows hope for treating inhalant abuse
8. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
9. Cigarette smoke causes breaks in DNA and defects to a cells chromosomes, Pitt study finds
10. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
11. Phase II trials of second-generation antisense cancer drug planned following successful early study

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: DNA registry study links among genetics environment disease

(Date:5/21/2015)... According to a new ... Software, Services), by Applications (Surveillance (Airborne, Maritime, Land), ... (Military & Defense & Commercial) - Global Forecast ... is expected to grow from $7252.0 Million in ... Compound Annual Growth Rate (CAGR) of 6.6%. ...
(Date:5/21/2015)... 21, 2015 The Sync Project™ , ... for health, today announced a collaborative partnership with ... will center on collaboration on original research, joint course ... in the collaboration, The Sync Project and BerkleeICE are ... Medicine" in the 2015-2016 academic year.  ...
(Date:5/20/2015)... May 20, 2015 ... has announced the addition of the  ... Iris Recognition Market"  report to their ... research service analyses trends in the ... and commercial sectors, globally. Despite hardware ...
Breaking Biology News(10 mins):Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 2The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 3Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2
(Date:5/22/2015)... May 22, 2015 Charm Sciences, ... Department of Agriculture (USDA), Grain Inspection, Packers and ... contract to Charm Sciences to monitor aflatoxin in ... (water-based) and ROSA FAST Aflatoxin Quantitative Test (solvent-based). ... Test uses Water Extraction Technology to extract ...
(Date:5/22/2015)... 22, 2015 Knowledgent , the ... that explores the potential of big data analytics in ... was developed to help life sciences and healthcare organizations ... to gain critical business insights. , The life sciences ... data driven by patient profiling, compliance and regulatory requirements, ...
(Date:5/22/2015)... 22, 2015 Baylor Research Institute (BRI) ... Genomics Research Institute (TGen) in Phoenix, AZ ... accelerating early detection and treatments for patients with a broad ... will lead to new clinical trials and access to technology ... gap from bench to bedside across Baylor Scott ...
(Date:5/21/2015)... SQI Diagnostics Inc. ("SQI" or the "Company") (TSX-V: SQD; ... proprietary technologies and products for advanced microarray diagnostics, today ... fiscal quarter ended March 31, 2015. ... with our existing customers and to develop new opportunities," ... SQI. "The delivery of a fully automated sqidlite™ system ...
Breaking Biology Technology:USDA-GIPSA (FGIS) Awards 5 Year Contract for Aflatoxin Tests to Charm Sciences 2New White Paper Explores the Potential of Big Data Analytics in Life Sciences and Healthcare 2Precision Medicine Collaboration to Increase Options for Cancer Patients 2Precision Medicine Collaboration to Increase Options for Cancer Patients 3Precision Medicine Collaboration to Increase Options for Cancer Patients 4SQI Diagnostics Reports Second Quarter Financial Results 2SQI Diagnostics Reports Second Quarter Financial Results 3SQI Diagnostics Reports Second Quarter Financial Results 4SQI Diagnostics Reports Second Quarter Financial Results 5SQI Diagnostics Reports Second Quarter Financial Results 6SQI Diagnostics Reports Second Quarter Financial Results 7SQI Diagnostics Reports Second Quarter Financial Results 8
Cached News: