HOME >> BIOLOGY >> NEWS
Dec. 17 JAMA study shows new 'biologic' drug reduces psoriasis symptoms, improves quality of life

MAYWOOD, Ill. A new "biologic" drug, efalizumab, reduces the thick, red, scaly skin lesions of psoriasis, and improves patient quality of life, according to a study in the Dec. 17 Journal of the American Medical Association.

"Biologics are a new approach to treating psoriasis," said lead author Dr. Kenneth Gordon, director of the Loyola Psoriasis Center, Loyola University Health System, Maywood, Ill. "The symptom relief with biologics is achieved without many of the side effects of traditional psoriasis treatment."

Gordon and colleagues conducted a double-blind, placebo-controlled study of efalizumab on 556 adult psoriasis patients at 30 centers in the U.S. and Canada. Patients received weekly injections of the drug or a placebo for three months. Researchers assessed the extent of the psoriasis on the head, upper and lower limbs, and trunk of each patient. In addition, they rated the degree of scaling and thickness.

"Psoriasis is triggered by an immune system response that induces skin cells to grow too quickly," said Gordon, associate professor of medicine, division of dermatology, Loyola University Chicago Stritch School of Medicine, Maywood, Ill. "The skin cells also do not mature normally. As a result, the skin piles up and forms red, scaly, thick plaque lesions.

For the study, patients completed a questionnaire asking how psoriasis affects their daily life, work and their relationships. They also reported symptoms, including pain, itching, bleeding, burning and scaling.

"Biologics are injected, instead of swallowed, and block immune cells that produce the dry, flaky skin," said Gordon, who serves on the National Psoriasis Foundation's medical board. Efalizumab modulates T-cells. Found in the blood supply, T-cells bolster the body's immune response.

The researchers evaluated the effects of efalizumab on health-related quality of life measures from both patient and physician perspective. "Psoria
'"/>

Contact: Joanne Swanson
jswanson@lumc.edu
708-216-2445
Loyola University Health System
16-Dec-2003


Page: 1 2

Related biology news :

1. Student science contest participation influences study, career choices, alumni say
2. New study shows hope for treating inhalant abuse
3. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
4. Cigarette smoke causes breaks in DNA and defects to a cells chromosomes, Pitt study finds
5. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
6. Phase II trials of second-generation antisense cancer drug planned following successful early study
7. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
8. Indiana University, EPA to study airborne PCBs
9. K-State, other universities to study how climate affects plant evolution
10. USC study links historical increases in life span to lower childhood exposure to infection
11. Washington University in St. Louis leads group studying aging process

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/15/2019)... ... 2019 , ... Erchonia, the global leader in the manufacturing ... in Orlando & 18th Annual Golf Tournament. The invite-only, four-day event starts ... Melbourne. , The first day will kick off with training and roundtable discussions ...
(Date:10/10/2019)... ... 2019 , ... Mindray, a global developer of technologies and ... of Anesthesiologists 2019 Annual Meeting to visit exhibit #841 and discover the operating ... will provide more than 14,000 healthcare professionals from around the world the opportunity ...
(Date:10/8/2019)... ... 2019 , ... The future of medicine in the 21st century will focus ... longer, healthier lives. But it will be up to each individual to make healthy ... Chief Strategy Officer and Co-Founder of the Institute for Systems Biology and Senior Vice ...
Breaking Biology News(10 mins):
(Date:9/24/2019)... (PRWEB) , ... September 24, 2019 , ... Drug resistance ... by the World Health Organization, with MRSA becoming one of the most serious concerns. ... were 1,218 reported cases of community-associated MRSA (CA-MRSA), or a seven-fold of the figure ...
(Date:9/22/2019)... ... September 20, 2019 , ... ... Neurotrophic Factor (BDNF) testing in serum . BDNF plays a vital role in ... growth and differentiation of new neurons in the brain involved in learning, memory, ...
(Date:9/17/2019)... (PRWEB) , ... September 16, 2019 , ... When a ... and kits that allow for the complete 3D characterization of tissues through the use ... transitioned into an imaging, image analysis and advanced cell culture focused contract research organization ...
(Date:9/11/2019)... ... 2019 , ... An upcoming episode of Advancements with Ted ... sequencing analysis. Check your local listings for more information. , Advancements will go ... and will explore its revolutionary pathogenic DNA analysis technology, which predicts in real-time, ...
Breaking Biology Technology:
Cached News: