HOME >> BIOLOGY >> NEWS
Development of hair depends on development of the hair channel

for further study. This experiment allowed them to observe how the absence of GATA-3 affects skin after the birth of the mice. What they observed was a malfunctioning set of channels: the three cell layers which form the channel were nearly completely absent.

But in addition to the channel defects, the hair shaft of the grafted skin was affected: hairs grew abnormally short and thick. According to the researchers, these hair shaft irregularities were caused by both faulty hair channels as well as internal disruptions.

"We found that some of the genes in the hair shaft were misexpressed, which implies a certain level of 'cross-talk' between the shaft and channel," says Kaufman.

"This means that when the two cell types are forming, there is some communication that takes place between them, probably to ensure proper growth."

Now that the researchers have unmasked an important transcription factor controlling the fate of the hair channel, their next step is to identify the ultimate mastermind -- the extracellular signaling protein required for the activation of GATA-3. Says Fuchs, "Knowing what externally promotes hair channel lineage would round out our knowledge of the hair follicle as a whole."


'"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
14-Aug-2003


Page: 1 2 3 4

Related biology news :

1. Origin and Development of the Vertebrate Traits
2. GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
3. 2nd Annual CDB Symposium: Developmental Remodeling (March 29 - 31, 2004; Kobe, Japan)
4. The Virus-Cancer Link: Examining the Role of Viruses in the Development of Cancer
5. Development of prostate drug based on UT Southwestern research
6. ICSU to establish Science for Sustainable Development programme
7. Development of important immune cells relies on more complicated influences than scientist had thought
8. Forum on Research and Development in FY 2002 Budget
9. Population-Development-Environment in Namibia: background readings
10. Symposium Probes Impact Of Toxins On Development
11. Researchers Discover Mechanism Of Cleft Palate Development

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Development hair depends development the hair channel

(Date:11/5/2014)... diversity in their ability to identify scents and odors. ... their perceptual evaluation of odors, with women outperforming men ... Sex differences in olfactory detection may play a role ... one,s perception of smell, which is naturally linked to ... been suggested to be cognitive or emotional, rather than ...
(Date:11/4/2014)... PA) – Temple University School of Medicine announced ... winner, an initiative funded by the Bill & ... Professor of Obstetrics, Gynecology and Reproductive Sciences; and ... Temple University School of Medicine will pursue an ... "Maternal Blood Biomarkers to Assess Fetal Neurodevelopment.", Grand ...
(Date:11/4/2014)... --   3D scanner developer ... Fuel3D , a developer of 3D scanning solutions, today ... million (£4 million). This funding builds on the company,s initial ... paves the way for the commercial launch of the company,s ... was led by Chimera Partners and will be used to ...
Breaking Biology News(10 mins):The female nose always knows: Do women have more olfactory neurons? 2Temple University School of Medicine receives Grand Challenges Explorations grant 2Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3
(Date:11/18/2014)... Alanda Software, a leading global ... announced today that a top tier global biopharmaceutical ... solution in both the U.S. and EU markets. ... Data Quality remediation portal, designed to help both ... improve their ability to capture, transmit and receive ...
(Date:11/18/2014)... November 18, 2014 2014 ... Industry is professional and in-depth report on ... basic information, including its definition, characterization, application, ... outline. This exploration covers the worldwide business ... industry examination covering macroeconomic environment & financial ...
(Date:11/18/2014)... Calif. , Nov. 18, 2014  Asterias ... company in the emerging field of regenerative medicine, ... AST-OPC1 (oligodendrocyte progenitor cells) for complete cervical spinal ... of ten "Top Advanced Therapies Projects to Watch" ... delighted to receive this significant industry honor, which ...
(Date:11/17/2014)... 17, 2014 The new METTLER ... " describes the challenges of becoming the first ... status for calibration weights in the microgram range. ... manufacturers and any scientists involved in nanotechnology applications ... handling, manufacturing and calibration of weights in the ...
Breaking Biology Technology:Alanda Software Completes Successful Implementation of Global Data Quality & Vendor Management Solution for Top Tier Global Biopharmaceutical Company 2PTMEG Market: 2019 Global Polytetrahydrofuran Industry Development Trends & Analysis Now at DeepResearchReports.com 2PTMEG Market: 2019 Global Polytetrahydrofuran Industry Development Trends & Analysis Now at DeepResearchReports.com 3Asterias Biotherapeutics Named as a "Top Advanced Therapies Projects to Watch" and Will Present at the Therapeutic Area Partnerships Conference 2Asterias Biotherapeutics Named as a "Top Advanced Therapies Projects to Watch" and Will Present at the Therapeutic Area Partnerships Conference 3New White Paper on Microgram Weights Describes How to Achieve Traceable Measurement Down to 0.05 Milligrams 2
Cached News: