HOME >> BIOLOGY >> NEWS
Development of hair depends on development of the hair channel

for further study. This experiment allowed them to observe how the absence of GATA-3 affects skin after the birth of the mice. What they observed was a malfunctioning set of channels: the three cell layers which form the channel were nearly completely absent.

But in addition to the channel defects, the hair shaft of the grafted skin was affected: hairs grew abnormally short and thick. According to the researchers, these hair shaft irregularities were caused by both faulty hair channels as well as internal disruptions.

"We found that some of the genes in the hair shaft were misexpressed, which implies a certain level of 'cross-talk' between the shaft and channel," says Kaufman.

"This means that when the two cell types are forming, there is some communication that takes place between them, probably to ensure proper growth."

Now that the researchers have unmasked an important transcription factor controlling the fate of the hair channel, their next step is to identify the ultimate mastermind -- the extracellular signaling protein required for the activation of GATA-3. Says Fuchs, "Knowing what externally promotes hair channel lineage would round out our knowledge of the hair follicle as a whole."


'"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
14-Aug-2003


Page: 1 2 3 4

Related biology news :

1. Origin and Development of the Vertebrate Traits
2. GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
3. 2nd Annual CDB Symposium: Developmental Remodeling (March 29 - 31, 2004; Kobe, Japan)
4. The Virus-Cancer Link: Examining the Role of Viruses in the Development of Cancer
5. Development of prostate drug based on UT Southwestern research
6. ICSU to establish Science for Sustainable Development programme
7. Development of important immune cells relies on more complicated influences than scientist had thought
8. Forum on Research and Development in FY 2002 Budget
9. Population-Development-Environment in Namibia: background readings
10. Symposium Probes Impact Of Toxins On Development
11. Researchers Discover Mechanism Of Cleft Palate Development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/15/2016)... , Dec. 15, 2016 Advancements ... experience, health wellness and wellbeing (HWW), and ... in three new passenger vehicles begin to ... gesture recognition, heart beat monitoring, brain wave ... facial monitoring, and pulse detection. These will ...
(Date:12/12/2016)... 2016  Researchers at Trinity College, Dublin, are ... combining the material with Silly Putty. The mixture (known ... able to sense pulse, blood pressure, respiration, and ... The research team,s findings were published ... http://science.sciencemag.org/content/354/6317/1257 ...
(Date:12/7/2016)... India , December 7, 2016 According to a ... Machine Learning), Software Tool (Facial Expression, Voice Recognition), Service, Application Area, End User, ... is estimated to grow from USD 6.72 Billion in 2016 to USD 36.07 ... Continue Reading ... ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... ... January 19, 2017 , ... Genedata, ... (R&D), today announced the launch of Data Science Services , offering ... evolving field of precision medicine. , Data Science Services allows pharmaceutical ...
(Date:1/19/2017)... and GAITHERSBURG, Md. ... MKT: PIP) and Altimmune, Inc., a privately-held immunotherapeutics ... of a definitive agreement for the merger of ... current investors include Novartis Venture Fund, HealthCap, Truffle ... be a fully-integrated and diversified immunotherapeutics company with ...
(Date:1/19/2017)... AquaBounty Technologies, Inc. (AIM: ABTU; NASDAQ: AQB), ... and a majority-owned subsidiary of Intrexon Corporation (NYSE: ... listing of its common shares on the NASDAQ Stock ... "AquaBounty,s listing on NASDAQ represents an important milestone ... the U.S. markets as we advance plans for commercial ...
(Date:1/19/2017)... Ca (PRWEB) , ... January 18, 2017 , ... ... events for tech innovators, engineers, and scientists from around the world, was today ... News. The awards program is based entirely on merit and decided upon by ...
Breaking Biology Technology:
Cached News: