HOME >> BIOLOGY >> NEWS
Development of hair depends on development of the hair channel

for further study. This experiment allowed them to observe how the absence of GATA-3 affects skin after the birth of the mice. What they observed was a malfunctioning set of channels: the three cell layers which form the channel were nearly completely absent.

But in addition to the channel defects, the hair shaft of the grafted skin was affected: hairs grew abnormally short and thick. According to the researchers, these hair shaft irregularities were caused by both faulty hair channels as well as internal disruptions.

"We found that some of the genes in the hair shaft were misexpressed, which implies a certain level of 'cross-talk' between the shaft and channel," says Kaufman.

"This means that when the two cell types are forming, there is some communication that takes place between them, probably to ensure proper growth."

Now that the researchers have unmasked an important transcription factor controlling the fate of the hair channel, their next step is to identify the ultimate mastermind -- the extracellular signaling protein required for the activation of GATA-3. Says Fuchs, "Knowing what externally promotes hair channel lineage would round out our knowledge of the hair follicle as a whole."


'"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
14-Aug-2003


Page: 1 2 3 4

Related biology news :

1. Origin and Development of the Vertebrate Traits
2. GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
3. 2nd Annual CDB Symposium: Developmental Remodeling (March 29 - 31, 2004; Kobe, Japan)
4. The Virus-Cancer Link: Examining the Role of Viruses in the Development of Cancer
5. Development of prostate drug based on UT Southwestern research
6. ICSU to establish Science for Sustainable Development programme
7. Development of important immune cells relies on more complicated influences than scientist had thought
8. Forum on Research and Development in FY 2002 Budget
9. Population-Development-Environment in Namibia: background readings
10. Symposium Probes Impact Of Toxins On Development
11. Researchers Discover Mechanism Of Cleft Palate Development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/22/2016)... March 22, 2016 ... Sensors Market for Consumer Industry by Type (Image, ... Application (Communication & IT, Entertainment, Home Appliances, ... Forecast to 2022", published by MarketsandMarkets, the ... to reach USD 26.76 Billion by 2022, ...
(Date:3/15/2016)... --> --> ... Research "Digital Door Lock Systems Market - Global Industry Analysis, ... global digital door lock systems market in terms of revenue ... forecast to grow at a CAGR of 31.8% during the ... enterprises (MSMEs) across the world and high industrial activity driving ...
(Date:3/11/2016)... , March 11, 2016 ... market research report "Image Recognition Market by Technology (Pattern ... and Advertising), by Deployment Type (On-Premises and Cloud), by ... 2022", published by MarketsandMarkets, the global market is expected ... USD 29.98 Billion by 2020, at a CAGR of ...
Breaking Biology News(10 mins):
(Date:5/27/2016)... ... ... Weeks after hosting a carpal tunnel syndrome workshop with Dr. Oz on ... of the Fitzmaurice Hand Institute, has announced the addition of MRI diagnostic imaging services ... only 1 of about 3 currently available in the United States. Developed specifically for ...
(Date:5/27/2016)... NC (PRWEB) , ... May 27, 2016 , ... Doctors ... analyzing dozens of studies on the BRCA-1 associated protein (BAP1) gene and its link ... the website. Click here to read the full article now. , The ...
(Date:5/27/2016)... , May 27, 2016 At ... investors playing in this space know that volatility is what ... featured companies on ActiveWallSt.com: Synta Pharmaceuticals Corp. (NASDAQ: ... Lpath Inc. (NASDAQ: LPTN ), and Heat Biologics ... gain access to the technical alerts for these stocks at: ...
(Date:5/26/2016)... Jersey and READING, England ... Indegene ( http://www.indegene.com ), a leading global ... life science, pharmaceutical and healthcare organisations and TranScrip ... innovative scientific support throughout the product lifecycle, today ... the launch of IntraScience.      (Logo: ...
Breaking Biology Technology:
Cached News: