HOME >> BIOLOGY >> NEWS
Development of hair depends on development of the hair channel

for further study. This experiment allowed them to observe how the absence of GATA-3 affects skin after the birth of the mice. What they observed was a malfunctioning set of channels: the three cell layers which form the channel were nearly completely absent.

But in addition to the channel defects, the hair shaft of the grafted skin was affected: hairs grew abnormally short and thick. According to the researchers, these hair shaft irregularities were caused by both faulty hair channels as well as internal disruptions.

"We found that some of the genes in the hair shaft were misexpressed, which implies a certain level of 'cross-talk' between the shaft and channel," says Kaufman.

"This means that when the two cell types are forming, there is some communication that takes place between them, probably to ensure proper growth."

Now that the researchers have unmasked an important transcription factor controlling the fate of the hair channel, their next step is to identify the ultimate mastermind -- the extracellular signaling protein required for the activation of GATA-3. Says Fuchs, "Knowing what externally promotes hair channel lineage would round out our knowledge of the hair follicle as a whole."


'"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
14-Aug-2003


Page: 1 2 3 4

Related biology news :

1. Origin and Development of the Vertebrate Traits
2. GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
3. 2nd Annual CDB Symposium: Developmental Remodeling (March 29 - 31, 2004; Kobe, Japan)
4. The Virus-Cancer Link: Examining the Role of Viruses in the Development of Cancer
5. Development of prostate drug based on UT Southwestern research
6. ICSU to establish Science for Sustainable Development programme
7. Development of important immune cells relies on more complicated influences than scientist had thought
8. Forum on Research and Development in FY 2002 Budget
9. Population-Development-Environment in Namibia: background readings
10. Symposium Probes Impact Of Toxins On Development
11. Researchers Discover Mechanism Of Cleft Palate Development

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Development hair depends development the hair channel

(Date:10/15/2014)... Fred Alt will be awarded the 44th Rosenstiel Award ... for his pioneering research exploring the mechanisms of genomic ... cancer cells. Alt is the second alumnus to win ... Nobel Prize in 2003. , Alt is the Charles ... at Harvard Medical School and an investigator at the ...
(Date:10/14/2014)... house fly genome for the first time, revealing robust ... that thrives in pathogen-rich dung piles and garbage heaps. ... Genome Biology , will increase understanding of house ... adapt to resist insecticides, which could lead to novel ... and transmit more than 100 human and animal diseases, ...
(Date:10/14/2014)... of scientists led by researchers at the University ... of Miami Miller School of Medicine (UMMSM) have ... underlying bipolar (manic depressive) disorder, a breakthrough that ... affective disorder, as well as depression and other ... online this week in Nature Molecular Psychiatry ...
Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2House fly genome reveals expanded immune system 2Rare genetic disease protects against bipolar disorder 2Rare genetic disease protects against bipolar disorder 3
(Date:10/19/2014)... 19, 2014 The Asia-Pacific Bromine ... in Asia-Pacific with analysis and forecast of revenue. ... Pacific Bromine Market report, to get an idea ... a glimpse of the segmentation in the Asia-Pacific ... and figures. , http://www.micromarketmonitor.com/market/asia-pacific-bromine-6741503144.html , ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 The report ... Market Share, Trade, Prices, Geography Trend and Forecast (2011 ... sales category, and geography and studies the major market ... North America, Europe, and Asia. , The global chocolate ... 2010.to $98.3 billion in 2016 at an estimated CAGR ...
(Date:10/19/2014)... According to market research report “Outdoor Wi-Fi ... gateways)]- Global Advancements, Forecasts and Analysis (2013 - ... market with analysis and forecasting of the global ... drivers and the restrains for this market with ... , Browse 65 market data tables and 69 ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... - Trends and Forecasts to 2019", analyzes the ... in order to understand the industry details such ... opportunities across various geographic regions. , Browse 81 ... 202 Slides and in-depth TOC on “1,6-Hexanediol Market ...
Breaking Biology Technology:The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5
Cached News: