Pratim Biswas, Ph.D.,Stifel & Quinette Jens Professor of Environmental Engineering Sciences and head of Environmental Engineering Sciences at Washington University, combines an electrical field with soft X-rays and smart catalysts to capture and destroy bioagents such as the smallpox virus.
"When the aerosol particles come into the device they are charged and trapped in an electrical field," Biswas explained. "Any organic material is oxidized, so it completely deactivates the organism."
Biswas noted that conventional corona systems do not charge and effectively trap nanometer-sized particles, such as viruses. But his invention combines soft x-rays with a conventional corona that has been proven to be very effective at charging and trapping particles in a range of sizes.
On the walls of the device, Biswas has coated nanoparticles that catalyze the oxidation. These nanoparticles are "smart" objects that are turned "on" and "off" by irradiation.
"This smart catalyst is unique," Biswas said. "If we should encounter some organism that is very difficult to degrade, I can engineer my smart catalysts to function so that they will oxidize those molecules."
Biswas and his collaborators have tested the device using non-potent polio virus and have achieved 99.9999 percent efficiency. He currently is collaborating with the Midwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research (MRCE) and his Washington University colleague, Lars Angenent, to identify the mechanistic pathways of biomolecular degradation.
Contact: Tony Fitzpatrick
Washington University in St. Louis