HOME >> BIOLOGY >> NEWS
Dietary Lutein Inhibits Mammary Tumor Growth And Normalizes Immune Balance In Tumor-Bearing Mice

Washington, DC, April 18, 1999 -- The carotenoid antioxidant lutein can normalize immune system balance in mammary tumor-bearing mice, effectively slowing tumor growth, according to a study presented today at the Federation of American Societies for Experimental Biology 1999 annual meeting.

"Tumor-bearing mice that were fed chow containing lutein had significantly smaller tumor growth than the mice on regular chow," said Boon Chew, Ph.D., Department of Animal Science, Washington State University. "Lutein normalized their immune response, enabling them to better fight the tumors."

Chew and his colleagues investigated the role of lutein in tumor immunity by examining hoe lutein stimulates the numbers and functionality of immune cells that suppress tumor development. Mice were fed a diet containing zero (control), 0.002, or 0.2 percent lutein (by weight) from marigold extract. After two weeks, half the mice were inoculated with mammary tumors. Researchers then assessed the blood and tissue lutein intake, tumor growth, changes in immune cell populations and the production of cytokines (soluble mediators).

After six weeks, mice that were fed chow with lutein had significantly smaller tumors than the mice on regular chow. While tumor progression suppressed the number of immune cells lutein prevented this suppression. Also, lutein increased the production of interferon gamma (IFNg) and interleukin-2. Researchers concluded that lutein normalized the immune balance in the tumor-bearing mice and increased the production of IFN, thereby maintaining an effective anti-tumor response.

Dr. Chew's previous research established that dietary lutein from marigold extract inhibited the growth of mammary tumors in mice. In addition, they showed that lutein can regulate gene activity in immune cells. Further research is needed to confirm speculation that lutein may exert its anti-tumor activity through its immuno-stimulatory action.

In ad
'"/>

Contact: Anne Tramer
atramer@selz.com
312-372-7090
Selz/Seabolt Communications
18-Apr-1999


Page: 1 2

Related biology news :

1. Dietary supplement shows promise for improving immune function in the elderly
2. Dietary supplement many not lower prostate cancer risk
3. Dietary ginger may work against cancer growth
4. Dietary component kills bacterial cause of ulcers and stomach cancer
5. Dietary soy reduces pain, inflammation in rats
6. Dietary changes can lower colon cancer risk in families with a history of the disease
7. Dietary supplements make old rats youthful, may help rejuvenate aging humans, according to UC Berkeley study
8. Dietary approaches to stop hypertension diet reduces cholesterol and long-term cardiovascular risk
9. Dietary study finds marijuana users have normal nutritional status, risky lifestyle habits
10. Dietary fibre supplements may be harmful
11. Dietary fat itself not likely to cause breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2017)... , Mar. 23, 2017 Research and Markets ... Market Analysis & Trends - Industry Forecast to 2025" report ... ... at a CAGR of around 8.8% over the next decade to ... report analyzes the market estimates and forecasts for all the given ...
(Date:3/20/2017)... Germany , March 20, 2017 At this ... Hamburg -based biometrics manufacturer DERMALOG. The Chancellor came to the DERMALOG ... is this year,s CeBIT partner country. At the largest German ... biometrics in use: fingerprint, face and iris recognition as well as DERMALOG´s ... ...
(Date:3/9/2017)... Australia , March 9, 2017 4Dx ... prestigious World Lung Imaging Workshop at the University of ... was invited to deliver the latest data to world ... recognised event brings together leaders at the forefront of ... in lung imaging. "The quality of ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... ... April 20, 2017 , ... USDM Life Sciences , the leading ... healthcare industries, is pleased to announce Holger Braemer as Vice President of ... GmbH” based in Germany. , Braemer is an integral part of USDM’s expansion ...
(Date:4/20/2017)... ... April 20, 2017 , ... NetDimensions appoints Bill Mastin, a learning ... 20 years of experience in the learning technologies industry, Mastin joins NetDimensions from the ... Technologies Group plc (LTG). At LEO, Mastin served as SVP of the North America ...
(Date:4/20/2017)... ... 2017 , ... Energetiq Technology , a world leader ... Executive Officer (CEO) Debbie Gustafson has been appointed to the SEMI North America ... the electronics manufacturing supply chain. The mission of the SEMI NAAB is to ...
(Date:4/20/2017)... ... April 20, 2017 , ... Open Therapeutics and ... (IP) sharing and commercialization model. , The Center for Advancing Innovation helps institutions ... this effort is bringing the IP to the attention of the entrepreneurial community ...
Breaking Biology Technology:
Cached News: