HOME >> BIOLOGY >> NEWS
Differences in response to amphetamines found between males and females pre-puberty

While some Internet sites advise parents that stimulants have the same effect on children as adults, new research on mice indicates this is not the case. Researchers conclude that further differentiation must be made based on gender.

PITTSBURGH, Pa. -- Amphetamine-like drugs are used to treat attention-deficit-hyperactivity disorder (ADHD). These stimulants help people with ADHD learn. They also improve the ability to concentrate, make one less easily distracted, make one less impulsive, and improve ones memory. Children with ADHD are provided drugs like Ritalin upon the recommendation of a physician. Yet, there is little in the research that suggests male and female children may exhibit biological differences in the responses to these stimulants.

Newly released research findings from experiments with mice have established a maturational response to drugs between the known postnatal (up to seven-10 days in rats and mice) and pubertal (around five-six weeks in rats and mice) stages. The findings reveal that differences between males and females in response to drugs begins at an earlier stage than previously believed. During the period after birth, female mice displayed a higher sensitivity to amphetamine well before the onset of puberty, but also well after the early postnatal determination of hormone regulation.

These findings offer a new understanding of male/female differences in brain function and the response to stimuli.

The previous literature focused on two general stages of maturation: (1) The early postnatal "critical period" when sex differences in later hormonal regulation are established (for comparison, mice are born at a stage of brain maturation roughly comparable with a seven-month human fetus) and (2) The time of puberty when sex differences in structure, function, and behavior are manifested.

The authors of the current study, Differential Sex Effects on Exploratory Behavior in Young Mice
'"/>

Contact: Donna Krupa
703-967-2751
American Physiological Society
18-Oct-2001


Page: 1 2 3

Related biology news :

1. Sex Differences in Cardiovascular Disease
2. Differences between boys and girls show less than three weeks into pregnancy
3. Autoimmune Diseases Study Shows Differences Between Men And Women
4. Evaluation Of The Two Types Of Cardiac Pacemakers Indicates Only Modest Differences In Value
5. Sex Differences In Heart Disease May Be Due To Enzyme That Breaks Down Fat
6. Malnutrition Impacts Longevity Of Females More Than Males And Shows Gender Differences In Fruit Flies
7. Columbia research to examine gene influence on severity of peridontal disease, therapy response
8. Protective gene may enhance vaccine responses
9. Activated signaling pathway may predict lung cancer patients response to gefitinib
10. Duke study disputes idea that trees can relocate quickly in response to climate change
11. Researchers develop better understanding of immune response to viral infection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/12/2019)... ... April 11, 2019 , ... Zen Nutrients, a visionary ... help decrease opioid abuse by offering over-the-counter vitamin and supplement assistance to qualified ... to 50% off. , In 2019, Zen Nutrients committed to donate up to ...
(Date:4/9/2019)... FLORENCE, S.C. (PRWEB) , ... April 09, 2019 , ... ... Novalis Certified Cancer Center following a rigorous and voluntary audit conducted by ... , One of only eight Novalis Certified Centers in the United States, McLeod is ...
(Date:4/4/2019)... ... April 02, 2019 , ... Orbsen Therapeutics, a ... immunotherapies, announced it will move its base of operations from the National University ... newly created biotechnology park in Galway, Ireland. , “With four clinical trials in ...
Breaking Biology News(10 mins):
(Date:4/12/2019)... ... April 12, 2019 , ... An ... and will educate about innovative tools and devices being used to enhance cognitive ... more information. , This segment of Advancements will focus on Sound for Life, ...
(Date:4/9/2019)... ... ... The American Society of Gene & Cell Therapy (ASGCT) is ... addition to the presidential line of succession, at the 22nd Annual Meeting . ... for a three-year term (2019-2021). , All five incoming members of the ASGCT ...
(Date:4/4/2019)... ... April 03, 2019 , ... ... intimate off-the-record collaboration and dialogue, today announces its Boston CEO conference to be ... into the industry’s challenges and opportunities with high-level panels and discussions from past, ...
(Date:3/23/2019)... ... March 22, 2019 , ... ... and analysis to a team of researchers at Nnamdi Azikiwe University in Anambra ... Nneka R. Agbokoba, PhD, of the Department of Medical Laboratory Sciences and Deputy ...
Breaking Biology Technology:
Cached News: