HOME >> BIOLOGY >> NEWS
Discovery helps explain how cells package DNA

es the histone proteins by adding chemical units known as acetyl groups.

The present study shows that the Hat B enzymes not only chemically modify histone proteins in cytoplasm--the region of the cell outside the nucleus--but that they remain attached to the histones as the proteins travel into the nucleus.

There, Parthun and his colleague, Xi Ai, a graduate student in The Ohio State University biochemistry program, found that the molecular threesome is joined by a fourth member, the newly discovered protein, Hif1p.

Last, the complex is joined by a fifth and still-unidentified protein that helps with that final step: adding the histone to DNA to form chromatin.

Next, Parthun wants to learn why histones must be modified by the addition of acetyl groups during chromatin assembly. He also wants to understand the role of the Hif1 protein in the process and identify the unknown protein that's needed for the final step of chromatin assembly.


'"/>

Contact: Darrell E. Ward
Ward-15@medctr.osu.edu
614-293-3737
Ohio State University
30-Apr-2004


Page: 1 2

Related biology news :

1. Discovery of new shrimp species adds to unique family
2. Discovery of tiny microbes in ancient Greenland glacier may define limits for life on Earth
3. Discovery in parasite movement may offer insights into malaria
4. Scientists find second way to kill cancer cells: Discovery opens possibilities for new therapies
5. GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
6. Discovery offers clues to origin of life
7. Discovery could improve anemia treatment in patients
8. Discovery could lead to better treatment for cryptosporidum infections
9. Discovery of brain disorder gene paves way for genetic test
10. Discovery may be first plant cell surface molecule that halts cell proliferation
11. Discovery may help in war against fire ants

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/4/2020)... ... July 03, 2020 , ... ... earn outstanding recognition and multiple awards for not only the products and treatments ... SoME® Skincare and Vivace® Microneedle RF. All the brands built by ABM have ...
(Date:6/28/2020)... ... June 25, 2020 , ... Genedata, ... that it has entered into a multi-year contract with Merus N.V., a ... translational and clinical research strategy to discover and develop ground-breaking drugs. The ...
(Date:6/23/2020)... (PRWEB) , ... June 22, 2020 , ... The field ... Typically, ligand binding assays (LBA) have dominated this area. However, the use of mass ... years. , This now necessitates the question “How do you choose which approach to ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... Ore. (PRWEB) , ... August 13, 2020 , ... ... the creation of its Scientific Advisory Board (SAB) to research the medical potential ... cannabis can be enhanced when combined with terpenes. The board is focused on expanding ...
(Date:8/7/2020)... WOODLANDS, Texas (PRWEB) , ... August 06, 2020 ... ... therapy and DNA vaccine industries, announces it has closed on the purchase of ... Technology Park in Conroe, TX and includes over 21 acres in the initial ...
(Date:7/31/2020)... ... July 29, 2020 , ... Diversified Technologies, Inc. has introduced ... configured to drive Klystrons, TWTs, IOTs, and magnetrons. , DTI Radar Transmitter ... in a push-pull configuration; yielding fast fall time for a capacitive load. These ...
(Date:7/31/2020)... ... July 30, 2020 , ... ... the life sciences industry, today announced the release of its signature product ... Medical Science Liaisons (MSLs) and other field medical professionals. , Beacon ...
Breaking Biology Technology:
Cached News: