HOME >> BIOLOGY >> NEWS
Drug combination increases life span of mice with ALS

Montreal, April 1 2003 A new three-drug cocktail used to treat ALS, or Lou Gehrig's Disease, may increase life span and decrease disease progression according to a study conducted at the Research Institute of the McGill University Health Centre (MUHC). The study, published in today's issue of Annals of Neurology, is the first to look at this drug combination in a mouse model of ALS. This research was made possible by a partnership led by the Canadian Institutes of Health Research (CIHR), in conjunction with the ALS society of Canada and the Muscular Dystrophy Association of Canada (MDAC).

"Last year, we demonstrated that minocycline, a commonly prescribed antibiotic, on its own reduced disease progression, and delayed death in the ALS mice," says MUHC neuroscientist and senior author, Dr. Jean-Pierre Julien. "Findings from our current study show that a therapeutic approach based on a combination of minocycline with two other drugs is much more effective in delaying the onset of the disease and in increasing the longevity of the ALS mice."

"The results are very impressive," says Dr. Angela Genge, director of the ALS clinic at the Montreal Neurological Institute and Hospital. "The approach that Dr. Kriz and Dr Julien use is uniquely helpful in screening for potentially effective therapies in this cruel, currently incurable disease. Every gain gives us hope for the future."

"These research results give people who suffer from ALS hope, and show how well CIHR is working," said Dr. Rmi Quirion, Scientific Director of the Institute of Neurosciences, Mental Health and Addiction of the CIHR. "I have followed and admired Dr. Julien's work for many years and it is important that the Government of Canada invest in this kind of research."

"These results provide hope to ALS patients and their families," says Centre Hospitalier de l'Universite de Montreal (CHUM) ALS clinician Dr. Monique D'Amour. "Because there is little effective treatment for
'"/>

Contact: Christine Zeindler
christine.zeindler@muhc.mcgill.ca
514-934-1934
McGill University
1-Apr-2003


Page: 1 2 3

Related biology news :

1. Winning combination to build bone density in children
2. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
3. Complex cells likely arose from combination of bacterial and extreme-microbe genomes
4. Researchers zero in on new drug combination strategy
5. IUB researchers to investigate genetic recombinations causes and consequences
6. Mutated protein combination tied to excessive sugar production
7. Clinical study reports findings of combination therapy with DOXIL
8. Novel COX-2 combination treatment may reduce colon cancer risk
9. A combination of zinc and vitamin A may restore night vision in pregnant Nepalese women
10. Alcohol and thiamine deficiency together: a dangerous combination?
11. Inter-Element Recombination Between Retrotransposons May Be Strategy For Evolution Of Viruses Like HIV

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/4/2020)... ... July 03, 2020 , ... ... outstanding recognition and multiple awards for not only the products and treatments developed, ... Skincare and Vivace® Microneedle RF. All the brands built by ABM have received ...
(Date:6/28/2020)... (PRWEB) , ... June 25, ... ... of enterprise software solutions for biopharmaceutical R&D, today announced that it has ... developing innovative, full-length multispecific antibodies (Multiclonics®), to support their translational and clinical ...
(Date:6/23/2020)... ... June 22, 2020 , ... The field of quantitation of large ... (LBA) have dominated this area. However, the use of mass spectrometry in this field ... necessitates the question “How do you choose which approach to use (LBA or MS)?” ...
Breaking Biology News(10 mins):
(Date:6/11/2020)... (PRWEB) , ... June 08, 2020 , ... ... universal vaccine platform delivered through the use of proprietary clean viral vectors, recently ... in the United States. Greffex’s platform is the world’s most successful gene ...
(Date:6/2/2020)... ... June 01, 2020 , ... As ... encourage positive change in the world, enterprise security solutions provider bitsIO donated time ... people working from home during self-quarantines and shelter-in-place orders, companies are increasingly concerned ...
(Date:5/26/2020)... ... 26, 2020 , ... Brilliant , the leading smart home control and ... openers, announce a new integration to bring more convenience, simplicity, and security to the ... Aladdin Connect® can now be controlled from Brilliant’s in-wall touchscreen control panels and mobile ...
(Date:5/15/2020)... ... May 14, 2020 , ... ... working cell banks and hMSC bioprocess systems, today announced the launch of ... hMSC-derived extracellular vesicles (EVs). RoosterCollect™-EV-CC is the only system designed with hMSC-EV ...
Breaking Biology Technology:
Cached News: