Drugs from sea study finds sponge health link to bacteria

BALTIMORE, Md. Calif.--In research aimed at finding natural compounds from the sea for drugs and other products, a team of scientists report in the journal Marine Biology on a bacterium that seems to be an indicator for health of a marine sponge.

The team found that a type of sponge living along the Great Barrier Reef near Australia contains a "culturable" population of almost entirely one strain of bacteria, living in a close relationship with the porous sea animals but not in surrounding waters. There are also many "uncultured" bacteria in the sponge that scientists cannot yet grow.

"We have found that the culturable microbe population is very stable," reports Russell Hill of the University of Maryland Biotechnology Institute (UMBI). "The presence of this bacterium seems to be related to the health of the sponge and is a good model for our work." Some unhealthy specimens of the same type of sponge, Rhopaloeides odorabile, did not contain the bacterial strain, report Hill, a molecular microbiologist at UMBI's Center of Marine Biotechnology, and colleagues at the Australian Institute of Marine Science (AIMS).

Understanding the symbiosis of such microbes and sponges is a critical step in studying potential biologically active, possibly medicinal, compounds in such bacteria. Sponges are recognized as rich sources of new compounds with biologically active ingredients that could qualify as new medicinal drug candidates. In some cases the bioactive compounds are likely to come from bacteria rather than the sponges themselves..

A January 2001 study, published by the COMB/AIMS team, opened the possibility that bacteria living in marine sponges may be a rich source of future drugs. In the earlier study, they identified by gene sequencing studies that many of the uncultured bacteria from sponges surveyed were in a bacterial family Actinomycetes. For many decades, soil borne members of the microbe family have been the sources of 60 to 70 percent of to

Contact: Steve Berberich
University of Maryland Biotechnology Institute

Page: 1 2 3

Related biology news :

1. Drugs limit deadly side effects of graft-versus-host disease
2. Drugs, electronics, and green catalysts: The chemical year in review
3. Drugs on tap
4. Discovery Of A Molecule That Controls Bile Acids May Lead To New Cholesterol Drugs
5. UT Southwestern Researchers Find Way To Control Gene Activity, Opening Way For Cancer Drugs
6. New Findings On Receptor Regulation May Lead To Better Drugs For Diabetes
7. NASA Research Helps Map Protein Structures -- Key In The Development Of New Disease-Fighting Drugs
8. 15 Drugs, Dyes And Other Chemicals Newly Listed As Known Or Likely Human Carcinogens
9. Cholesterol Lowering Drugs Stall Disease Progression In People With Below-Average Blood Cholesterol Level
10. Some AIDS Patients May Show Resistance To Sulfa Drugs
11. Researchers Discover Existing Drugs May Prevent Enlarged Hearts

Post Your Comments:

(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: