HOME >> BIOLOGY >> NEWS
E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab

MADISON - A team of scientists headed by Frederick R. Blattner of the E. coli Genome Project in the Laboratory of Genetics at the University of Wisconsin-Madison has determined the complete genome sequence of the E. coli bacterium, it was reported today (Sept. 5) in the journal Science.

A genome is the sum total of the genes of an organism. Genes are encoded in the sequence of chemical base pairs that make up the intertwining strands of DNA. In the case of E. coli, a total of 4,403 genes have been identified in the 4,639,221 base pairs of DNA sequenced by the Wisconsin team. Of these, one-third are of completely unknown function.

E. coli holds a unique place in modern biology. It is arguably the single most studied cell in all of science. Humans have about 25 times as many genes as E. coli, but in the future a similar complete analysis will be possible for human DNA. For this reason E. coli is considered a model organism in the Human Genome Initiative of the National Institutes of Health (NIH).

For more than 70 years, Escherichia coli has been a mainstay of basic biology, and recent developments in biotechnology and genetic engineering have depended heavily on it. Related strains of E. coli are also responsible for several human diseases. Although not the first bacterial genome to be completed, E. coli is by far the most complex and the most eagerly awaited by scientists around the world.

"Determination of the complete inventory of the genes of organisms is one of the holy grails of biology, analogous to development of the periodic table of the elements in chemistry," said Blattner. "Once they are all known and relationships between them become evident, a classification system for understanding the basic functions of life can be erected."

E. coli's natural habitat is the lower intestinal tract of animals, including humans.

Originally isolated in 1922 from a convalescent diphtheria patient, the strain of E. coli sequenced
'"/>

Contact: Terry Devitt
trdevitt@facstaff.wisc.edu
608-262-8282
University of Wisconsin-Madison
3-Sep-1997


Page: 1 2 3 4

Related biology news :

1. Wiley publishes Welcome to the Genome: A Users Guide to the Genetic Past, Present, and Future
2. Genome-wide screen reveals new tricks of old genes
3. Genome of first fungal pathogen unveiled
4. Experimental Biology 2004 - Translating the Genome
5. European Virtual Institute for Genome Annotation receives 12 million Euro
6. Tools from the Human Genome Project reveal a versatile microbe
7. Francis Collins and Ari Patrinos receive Energy Secretarys Gold Award for Human Genome Project
8. Genomes of tiny microbes yield clues to global climate change
9. Genome researcher analyze chromosome 7
10. Genome sequence of bread mold revealed by international team, including Hebew University researcher
11. Genome analysis sheds light on drug-resistant pathogen

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... Report on Form 10-K on Thursday April 13, 2017 with the ... The ... section of the Company,s website at http://www.nxt-id.com  under "SEC Filings," ... 2016 Year Highlights: Acquisition of ...
(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... Rosalind™, the first-ever genomics analysis platform specifically designed for life science researchers ... honor of pioneering researcher Rosalind Franklin, who made a major contribution to ...
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia ... be hosting a Webinar titled, “Pathology is going digital. Is your lab ready?” ... pathology adoption best practices and how Proscia improves lab economics and realizes an ...
(Date:10/11/2017)... ... October 11, 2017 , ... Singh Biotechnology ... drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of Transcription ... is able to cross the cell membrane and bind intracellular STAT3 and inhibit ...
(Date:10/10/2017)... 2017 International research firm Parks Associates announced today ... the TMA 2017 Annual Meeting , October 11 in ... home security market and how smart safety and security products impact the ... Parks Associates: Smart Home Devices: ... "The residential security market has experienced ...
Breaking Biology Technology:
Cached News: