HOME >> BIOLOGY >> NEWS
E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab

by Blattner's team rose to prominence as an experimental organism in 1945 when it was used in the discovery of spontaneous gene transfer or bacterial sex. As a result, the strain, known as K-12, was universally adopted for fundamental work in biochemistry, genetics and physiology. In recent years, it has become the workhorse of biotechnology and is used as a living factory to produce human insulin and other medicines.

The most important result of the work reported today is the sequence itself, said Blattner. In January, the data were made freely available through on-line databases such as GenBank to scientists worldwide. The E. coli genome is a huge one, and required an additional nine months to describe in detail in Science. With more than 4.6 million bases, it is two or three times bigger than other bacteria sequenced to date.

Sequencing of the base pairs that make up DNA is analogous to deciphering a language. It is done with the aid of specialized chemical analysis machines, but can only be accomplished with considerable human effort. More than 269 people - including many undergraduates getting their first taste of science - participated in the project at the UW-Madison.

The individual chemical bases that make up the genome correspond to the letters of the genetic alphabet which, grouped into words and paragraphs corresponding to genes, are read by the living cell as the instructions for assembly and function of all of life's processes.

Knowledge of the genetic code, a major effort of modern biology, permits the scientist to translate the instructions for the purpose of understanding life processes, Blattner said. Knowing the precise order of the chemical base pairs for an entire genome allows the encoded life program to be read in its entirety leading, in principle, to a very complete level of understanding of physiological processes.

The report published in this issue of Science is a global analysis of the data collected by Blattner's team in c
'"/>

Contact: Terry Devitt
trdevitt@facstaff.wisc.edu
608-262-8282
University of Wisconsin-Madison
3-Sep-1997


Page: 1 2 3 4

Related biology news :

1. Wiley publishes Welcome to the Genome: A Users Guide to the Genetic Past, Present, and Future
2. Genome-wide screen reveals new tricks of old genes
3. Genome of first fungal pathogen unveiled
4. Experimental Biology 2004 - Translating the Genome
5. European Virtual Institute for Genome Annotation receives 12 million Euro
6. Tools from the Human Genome Project reveal a versatile microbe
7. Francis Collins and Ari Patrinos receive Energy Secretarys Gold Award for Human Genome Project
8. Genomes of tiny microbes yield clues to global climate change
9. Genome researcher analyze chromosome 7
10. Genome sequence of bread mold revealed by international team, including Hebew University researcher
11. Genome analysis sheds light on drug-resistant pathogen

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2016)...  IMPOWER physicians supporting Medicaid patients in ... standard in telehealth thanks to a new partnership with ... IMPOWER patients can routinely track key health measurements, such ... and, when they opt in, share them with IMPOWER ... local retail location at no cost. By leveraging this ...
(Date:3/31/2016)... R.I. , March 31, 2016  Genomics firm ... of founding CEO, Barrett Bready , M.D., who ... members of the original technical leadership team, including Chief ... President of Product Development, Steve Nurnberg and Vice President ... returned to the company. Dr. Bready served ...
(Date:3/23/2016)... 2016 Einzigartige ... und Stimmerkennung mit Passwörtern     ... MESG ), ein führender Anbieter digitaler Kommunikationsdienste, ... SpeechPro zusammenarbeitet, um erstmals dessen Biometrietechnologie einzusetzen. ... Möglichkeit angeboten, im Rahmen mobiler Apps neben ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... Ginkgo Bioworks , a leading organism design company ... as one of the World Economic Forum,s Technology ... companies. Ginkgo Bioworks is engineering biology to manufacture ... the nutrition, health and consumer goods sectors. The ... Fortune 500 companies to design microbes for their ...
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of ... the Cary 5000 and the 6000i models are higher end machines that use the ... of the spectrophotometer’s light beam from the bottom of the cuvette holder. , ...
(Date:6/23/2016)... Wausau, WI (PRWEB) , ... June 23, 2016 ... ... probiotic supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, ... supplements for over 35 years, is proud to add Target to its list ...
(Date:6/23/2016)... 23, 2016 A person commits a crime, and ... to track the criminal down. An outbreak of ... Drug Administration (FDA) uses DNA evidence to track down the ... Sound far-fetched? It,s not. The FDA has increasingly used a ... of foodborne illnesses. Put as simply as possible, whole genome ...
Breaking Biology Technology:
Cached News: