HOME >> BIOLOGY >> NEWS
Earliest evidence of hereditary genetic disorder discovered by Hebrew University researchers

The discovery of what is believed to be the oldest evidence yet found of a human hereditary genetic disorder has been announced by researchers at the Hebrew University of Jerusalem.

The researchers are Dr. Uri Zilberman and Patricia Smith, the Joel Wilbush Professor of Medical Anthropology, both of the Faculty of Dental Medicine of the Hebrew University and Dr. Silvana Condemi a senior researcher at the French Research Institute in Jerusalem. They are among the authors of an article in the June issue of the Journal of Human Evolution that details the finding of a disease known as amelogenesis imperfecta in the teeth of a fossil found in archaeological excavations in Ethiopia. The fossil is dated as 1.5 million years old and is from a two-year-old Homo erectus child. Homo erectus was a precursor of modern man.

According to Dr.Zilberman, this is the first recorded evidence from such an early prehistoric period of a hereditary disorder in which the specific genes responsible have been identified. Undoubtedly, he said, there are other hereditary diseases that have come down to us from prehistoric ancestors and which are yet to be discovered in fossil remains.

Amelogenesis imperfecta is a hereditary disorder that manifests itself in tooth enamel that is abnormal in structure, low in mineral content and hence subject to rapid wear and chipping. The Hebrew University researchers confirmed the clear presence of the disease in the fossil sample through x-ray and scanning electron microscope analyses. The disease appears relatively rarely today (one in 14,000 people in Israel, one in 8,000 in the U.S.). It is much more common in one area of Sweden (one in 700).


'"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-2-588-2904
The Hebrew University of Jerusalem
28-Jun-2004


Page: 1

Related biology news :

1. Earliest evidence of humans affecting aquatic ecology in Canada, United States
2. Earliest European modern humans found
3. Earliest evidence of lemurs discovered in Pakistan, far from their current home, Science reports
4. Earliest human ancestors discovered in Ethiopia
5. Earliest chewing herbivore ever found spurred vertebrate life on land, scientists find
6. Earliest Modern Tree Lived 360-345 Million Years Ago
7. Evidence For Earliest Maritime-Based Societies In The Americas Reported In Science Magazine
8. New evidence of radiation risk in childhood leukaemia
9. Oldest evidence for processing of wild cereals: starch grains from barley, wheat, on grinding stone
10. Study finds first evidence COX-2 enzymes can regulate DNA damage
11. Researchers find evidence that sea turtles navigate with magnetic maps

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/30/2019)... ... September 30, 2019 , ... Foresight ... manufacturing and other transformative technologies, announced the winners for the 2019 Foresight Institute ... other for Theory in nanotechnology/molecular manufacturing. , Established in 1993 and named in ...
(Date:9/30/2019)... ... September 30, 2019 , ... ... organization focused on molecular manufacturing and other transformative technologies, announced the 2018 ... College graduate or undergraduate student whose work is considered most notable in ...
(Date:9/25/2019)... ... 2019 , ... Deep Science Ventures (DSV), a new paradigm for ... funder of cancer research. , Deep Science Ventures was founded to create a better ... opportunity from the start, both at the industry and biological level. , Through ...
Breaking Biology News(10 mins):
(Date:9/24/2019)... ... September 24, 2019 , ... Personalized Stem Cells, ... site qualification for clinical trial sites and physician investigators. The clinical trial ... trial participants. , Clinical trial sites are currently located in San Diego and ...
(Date:9/17/2019)... , ... September 17, 2019 , ... ... Julie Delaney, Director, Project and Clinical Supplies Management, Asia Pacific (APAC) will present ... Farrer Hotel, Singapore, on Sept. 25-26, 2019. , On Thursday, Sept. 26, at ...
(Date:9/17/2019)... ... September 16, 2019 , ... When a lot of researchers think of Visikol, ... complete 3D characterization of tissues through the use of confocal and light sheet microscopy. ... and advanced cell culture focused contract research organization and today offers 3D tissue ...
(Date:9/11/2019)... ... September 09, 2019 , ... ... clinical trial randomization and drug supply chain management, today announced its new technology ... life sciences industry. , “The integration between Veeva Vault EDC and our IRT ...
Breaking Biology Technology:
Cached News: