HOME >> BIOLOGY >> NEWS
Early infection and rejection detection

TROY, N.Y. Julie Stenken, associate professor of analytical chemistry at Rensselaer Polytechnic Institute in Troy, N.Y., has received a four-year, $750,000 grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) to develop a new technique that can be used to study the body's reaction to medical implants at the cellular level. Millions of medical devices, including catheters, pacemakers, vascular grafts, and glucose sensors, are regularly implanted into humans. Despite the frequency of these procedures, implantation still poses a risk of serious side effects, including implant site infection and rejection of the implanted device. The microdialysis technique can provide information that may someday allow doctors to spot infection earlier and prevent rejection from occurring.

Tiny Samples Provide New Understanding
A microdialysis probe (the size of a 0.5 mm pencil lead) is used to withdraw a tiny sample of extracellular fluid at the site where the implant and the body's tissues meet. Analysis of the sample can detect the presence and amount of a variety of chemical markers called cytokines that may indicate early signs of responses to an implant such as infection or rejection. "If you can understand the chemical communication that is going on at the implantation site, you can ultimately bioengineer the site to make it do what is appropriate for the device," says Stenken. "The tools to measure these chemical reactions are just starting to become available to us." Stenken is collaborating with Albany Medical Center co-investigators Daniel Loegering and Michelle Lennartz.

The NIBIB coordinates with the biomedical imaging and bioengineering programs of other agencies and the National Institutes of Health to support imaging and engineering research with potential medical applications.

Stenken's microdialysis project is part of Rensselaer's focal effort to advance biotechnology discoveries for the benefit
'"/>

Contact: Joely Johnson
johnsj2@rpi.edu
518-276-6098
Rensselaer Polytechnic Institute
24-Jul-2003


Page: 1 2

Related biology news :

1. Berkeley Lab soil scientist Margaret Torn receives Presidential Early Career Award
2. Early detection hope for eye disease
3. Early clinical treatment can halt progression of Alzheimers disease, UCI researchers find
4. Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
5. Early predictor of breast cancer aggressiveness
6. Early treatment confirmed as key to stroke recovery
7. Early identification of kidney disease cost-effective only when directed at high-risk patients
8. Early promise for treatment of Ebola
9. Early treatment can prevent severe vision loss in premature infants
10. Early hominids may have behaved more human than we had thought
11. Early-life environments shape development of stress behaviors and learning abilities in mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2019)... , ... April 04, 2019 , ... ... with integrated linear encoders providing 0.05 microns and 0.005 microns resolution, respectively. The ... and drive variations are available, from fast DC-servo motors with linear encoders and ...
(Date:4/4/2019)... ... April 02, 2019 , ... The live session ... into the connectivity between product risk management (ISO 14971) and the clinical risk ... process. , With increasing global regulation and reimbursement challenges faced by medical device ...
(Date:4/1/2019)... (PRWEB) , ... April 01, 2019 , ... ... and System for Characterizing Skin Related Conditions” by the US Patent and Trademark ... The patent is an invention by uBiome collaborators Dr. Zachary Apte, Dr. ...
Breaking Biology News(10 mins):
(Date:4/16/2019)... ... 2019 , ... Fulcrum Biometrics , a leading provider ... Pacific (BSP), the largest regionally owned bank in the South Pacific, selected Fulcrum ... deliver a fingerprint-based Know Your Customer (KYC) banking solution that is being rolled ...
(Date:4/10/2019)... ... April 10, 2019 , ... After more than three months ... new kitchen is equipped with updated appliances and modern lighting and fixtures, and will ... , “We’ve seen tremendous growth in the demand for our team-building events ...
(Date:4/8/2019)... JORDAN, Utah and BOSTON (PRWEB) , ... April ... ... in delivering cloud-based enterprise-class unified communications and collaboration solutions, announced today the launch ... provides integration to an unprecedented range of business and contact-orientated applications while using ...
(Date:4/4/2019)... ... April 03, 2019 , ... ... off-the-record collaboration and dialogue, today announces its Boston CEO conference to be held ... the industry’s challenges and opportunities with high-level panels and discussions from past, present ...
Breaking Biology Technology:
Cached News: