HOME >> BIOLOGY >> NEWS
Effects of maternal myasthenia gravis on pregnancy and birth examined

ST. PAUL, MN ? A 33-year study of all births by women in Norway with Myasthenia Gravis (MG) confirms that MG is associated with an increased risk for complications during pregnancy, including a threefold higher incidence of preterm rupture of the amniotic membranes, and twice the occurrence of delivery by cesarean section. The study is reported in the November 25 issue of Neurology, the scientific journal of the American Academy of Neurology.

Data for the study was collected from the Medical Birth Registry of Norway, based on compulsory notification of all births in the country. The study included 127 births by women with MG and the 1.9 million births by women without MG.

Women with MG had twice the rate of cesarean section (17.3 percent) when compared to the control group (8.6 percent). Preterm rupture of amniotic membranes occurred three times more often ? or 5.5 percent ? compared to 1.7 percent of the general population.

MG is a chronic autoimmune disease that causes muscle weakness. In people with MG, cells of the immune system make protein antibodies that block nerve impulses to their muscles. The major symptom of MG is muscle weakness that is worsened by fatigue and generally improves with rest. The prevalence of MG is estimated at about 1 in 10,000.

About 15 percent of infants born to women with MG are thought to develop neonatal MG through the passage of MG antibodies between the mother and newborn. The symptoms are usually mild or moderate, and include poor sucking and muscle tone. In this study, neonatal MG occurred in about 4 percent of the newborns, but another 8 percent were observed with MG symptoms following birth.

According to study author Jana Midelfart Hoff, MD, Institute of Neurology, University of Bergen, "Pregnancy does not appear to worsen the long-term effects of MG in women, however the disorder sometimes manifests itself during pregnancy, primarily during the first trimester or shortly after delivery
'"/>

Contact: Kathy Stone
kstone@aan.com
651-695-2763
American Academy of Neurology
24-Nov-2003


Page: 1 2

Related biology news :

1. Effects of rare, devastating disease linked to shrinking of cells telomeres
2. Effects of global warming already being felt on plants and animals worldwide
3. Effects of iron-deficiency anemia in infants linger
4. Effects of ozone pollution threaten agricultural production on Long Island, NY, says Cornell plant pathologist
5. Effects of Muscular Dystrophy reversed by gene therapy, reports team fromChildrens National Medical Center and the University of Pittsburgh
6. Urine Tests Will Do Better Than Pelvic Exams To Save Teens From Serious Effects Of Sexually Transmitted Diseases, UCSF Analysis Shows
7. Experimental Drug Derived From Snake Venom Shows Promise In Reversing Effects Of Stroke
8. Vanderbilt Medical Students Study Effects Of Vibration On Infant Health
9. Early Nutrition In Babies May Have Long Term Effects On The Brain
10. Alcohol Consumption, Resistance To Its Effects Related To Levels Of Neurotransmitter, Say UW Researchers
11. DDT, PCBs, And Invasive Plants - USGS Scientists Examine The Effects Of Contaminant And Invasive Species On Wildlife

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/1/2020)... ... April 30, 2020 , ... ... an alliance with Corritori Consulting Inc., a biopharmaceutical and regulatory services advisor. The ... companion diagnostics industries. Flagship and Corritori are taking a collaborative approach to empower ...
(Date:4/30/2020)... N.M. (PRWEB) , ... April 28, 2020 , ... ... the world’s biggest challenges in agriculture and aquaculture with the mission of improving global ... at the 2020 F&A Next ' Next Heroes in Food- and Ag-Tech ' virtual ...
(Date:4/28/2020)... and FT. LAUDERDALE, Fla. (PRWEB) , ... April ... ... its official launch. The first-of-its-kind category-defining service was started by three teenagers with ... make a change in the world during the time of great need and ...
Breaking Biology News(10 mins):
(Date:5/5/2020)... ... 04, 2020 , ... Red Nucleus, a leading provider of ... that Informa Training Partners, a life sciences training company acquired by Red Nucleus ... immediately. , “The name change solidifies a stronger presence for Red Nucleus in ...
(Date:5/1/2020)... , ... April 30, 2020 , ... ... announced today, honoring the businesses, policies, projects, and concepts that are actively engaged ... bioprinter for living cells, which has taken out the top prize in the ...
(Date:4/22/2020)... ... April 20, 2020 , ... ... MA, announced today that Omixon’s founder and chairman Dr. Attila Berces returns as ... product Holotype HLA since 2014 before stepping into the CEO role in 2017. ...
(Date:4/18/2020)... (PRWEB) , ... April 17, 2020 , ... ... Science Foundation (NSF) Small Business Innovation Research (SBIR) program to support the expansion ... This funding from the NSF, which conducts a rigorous merit-based review process, ...
Breaking Biology Technology:
Cached News: