HOME >> BIOLOGY >> NEWS
Embryonic hope for damaged spines

NERVE cells derived from human embryonic stem cells and transplanted into paralysed rats have enabled the animals to walk again. The findings add to a growing number of studies that suggest embryonic stem cells could have a valuable role to play in treating spinal injuries.

The researchers, whose work was funded by stem cell giant Geron of Menlo Park, California, say trials on people could start in just two years. But the first trials are likely to involve patients with recent spinal cord injuries and localised damage. Treating people who have been paralysed for years or suffer from degenerative nerve diseases would be far more difficult.

Ways will also have to be found to prevent people rejecting the stem cells. One possible alternative to immunosuppressant drugs, Geron president Thomas Okarma told the meeting last week, would be to first give patients bone marrow stem cells from the same source as the nerve cells. This might trick the patients' immune system into developing tolerance.

Researchers are exploring a number of approaches to repairing damaged spines, including drugs that overcome spinal cells' reluctance to regrow, ways of bridging the gap between severed nerves and transplants of various tissues, including adult stem cells derived from bone marrow and nerve cells from the nose. Human trials of some treatments, such as using nose cells, have already begun.

But Okarma thinks adult cells have serious limitations as a mass-market treatment, because not many cells can be grown from a single source. That is not a problem with embryonic stem cells (ESCs). "One cell bank derived from a single embryo produces enough neurons to treat 10 million Parkinson's disease patients," says Okarma.

What's more, he claims, adult stem cells may not be as versatile. "At this moment, there is very little hard evidence that a bone marrow stem cell can turn into anything but blood or that a skin stem cell can become anything but skin." ESC
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
2-Jul-2003


Page: 1 2 3

Related biology news :

1. Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
2. Embryonic stem cell - based tissue engineering may help repair damaged heart muscle
3. Embryonic skin cells committed at an early age
4. Embryonic pig cell transplants halt rat diabetes
5. Embryonic pathway critical to growth of digestive tract tumors
6. Embryonic facial development subject to insult or repair longer than expected
7. Embryonic mouse stem cells reduce symptoms in model for Parkinsons disease
8. Statement Of The DFG Concerning "Questions Of Human Embryonic Stem Cells"
9. Molecular Control Mechanism Of Embryonic Development Unraveled
10. First Derivation Of Human Embryonic Stem Cells Reported In Science
11. Hopkins Research Team Cultures Long-Awaited Human Embryonic Stem Cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2019)... ... 29, 2019 , ... FileWave, the multi-platform endpoint management solution ... of version 13.1. The new version extends FileWave’s mobile device management features on ... release functionality. Version 13.1 builds on FileWave’s version 13 that was released in ...
(Date:5/31/2019)... ... ... Enso Discoveries Chief Executive Officer, Patrick Farley, is honored to give back to ... his gratitude and respect for those who have served their country. In honor of ... presented a check for $1,000 to the Green Beret Foundation, via former US Army ...
(Date:5/24/2019)... WOODLANDS, Texas (PRWEB) , ... May 24, 2019 , ... ... been published and is now available on the company’s global website. , Crystallography Times ... on single crystal X-ray diffraction. It serves the X-ray analysis community by presenting the ...
Breaking Biology News(10 mins):
(Date:5/2/2019)... , ... May 02, 2019 , ... Stay on top ... medical device and food industries. Access to all webinars is free, so be sure ... in your field! , Visit http://www.xtalks.com to see our upcoming webinars: , ...
(Date:4/25/2019)... ... , ... Frank is an albino, deaf Great Dane. His owners rescued him when he was ... issues. Despite his hearing impairment, he was always an active and playful pup. Frank bonded ... every day. As the two grew, playtime became rougher and Frank ended up injuring his ...
(Date:4/16/2019)... ... April 16, 2019 , ... ... their project partner, the U.S. Army Center for Environmental Health Research (USACEHR), with ... Combined In-Licensing/Out-Licensing.” , Blue Sources, a veteran-owned company located at the Frederick Innovative ...
(Date:4/12/2019)... , ... April 12, 2019 , ... ... developments in neurotechnology and will educate about innovative tools and devices being used ... local listings for more information. , This segment of Advancements will focus on ...
Breaking Biology Technology:
Cached News: